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Gong, Xinyu, Wang, Yingli, Tang, Yubin, Wang, Yaru, Zhang, Mingfang, Li, Miao, Zhang, Yuchao, Pan, Lifeng. ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy. SCIENCE ADVANCES[J]. 2023, 9(9): http://dx.doi.org/10.1126/sciadv.adf0824.
Wang, Hongbo, Zou, Yike, Li, Miao, Tang, Zhijun, Wang, Jiabao, Tian, Zhenhua, Strassner, Nina, Yang, Qian, Zheng, Qingfei, Guo, Yujiao, Liu, Wen, Pan, Lifeng, Houk, K N. A cyclase that catalyses competing 2+2 and 4+2 cycloadditions. NATURE CHEMISTRY[J]. 2023, 15(2): 177-+,
Liu, Zaizhou, Chen, Kaige, Dai, Jun, Xu, Peng, Sun, Wei, Liu, Wanlin, Zhao, Zhixin, Bennett, Steven P, Li, Peifeng, Ma, Tiancheng, Lin, Yuqi, Kawakami, Akinori, Yu, Jing, Wang, Fei, Wang, Chunxi, Li, Miao, Chase, Peter, Hodder, Peter, Spicer, Timothy P, Scampavia, Louis, Cao, Chunyang, Pan, Lifeng, Dong, Jiajia, Chen, Yong, Yu, Biao, Guo, Min, Fang, Pengfei, Fisher, David E, Wang, Jing. A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. CELL RESEARCH[J]. 2023, 33(1):
Liu, Guizhen, Du, Yanan, Fu, Tao, Han, Ying, Pan, Lifeng, Kang, Jingwu. Profiling protein interactions by purification with capillary monolithic affinity column in combination with label-free quantitative proteomics. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 1676: http://dx.doi.org/10.1016/j.chroma.2022.463273.
Jianping Liu, Yaru Wang, Danni Wang, Yingli Wang, Xiaolong Xu, Yuchao Zhang, Ying Li, Mingfang Zhang, Xinyu Gong, Yubin Tang, Liqiang Shen, Miao Li, Lifeng Pan. Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proceedings of the National Academy of Sciences of the United States of America[J]. 2022, 119(12):
Pischedda, Francesca, Cirnaru, Maria Daniela, Ponzoni, Luisa, Sandre, Michele, Biosa, Alice, Perez Carrion, Maria, Marin, Oriano, Morari, Michele, Pan, Lifeng, Greggio, Elisa, Bandopadhyay, Rina, Sala, Mariaelvina, Piccoli, Giovanni. LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation. BRAIN[J]. 2021, 144: 1509-1525,
Zixuan Zhou, Jianping Liu, Tao Fu, Ping Wu, Chao Peng, Xinyu Gong, Yingli Wang, Mingfang Zhang, Ying Li, Yaru Wang, Xiaolong Xu, Miao Li, Lifeng Pan. Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946963/.
Meng, Huyan, Wu, Guowei, Zhao, Xinsuo, Wang, Anhui, Li, Dekang, Tong, Yilun, Jin, Taijie, Cao, Ye, Shan, Bing, Hu, Shichen, Li, Ying, Pan, Lifeng, Tian, Xiaoxu, Wu, Ping, Peng, Chao, Yuan, Junying, Li, Guohui, Tan, Li, Wang, Zhaoyin, Li, Ying. Discovery of a cooperative mode of inhibiting RIPK1 kinase. CELL DISCOVERY[J]. 2021, 7(1):
Shan, Hengyue, Liu, Jianping, Shen, Jiali, Dai, Jialin, Xu, Gang, Lu, Kuankuan, Han, Chao, Wang, Yaru, Xu, Xiaolong, Tong, Yilun, Xiang, Huaijiang, Ai, Zhiyuan, Zhuang, Guanglei, Hu, Junhao, Zhang, Zheng, Li, Ying, Pan, Lifeng, Tan, Li. Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. CELL CHEMICAL BIOLOGY[J]. 2021, 28(6): 855-+, http://dx.doi.org/10.1016/j.chembiol.2021.04.020.
Zhang, Haijiao, Lin, Lin, Liu, Jianping, Pan, Lifeng, Lin, Zhijie, Zhang, Mingjie, Zhang, Jiong, Cao, Ying, Zhu, Jinwei, Zhang, Rongguang. Phase Separation of MAGI2-Mediated Complex Underlies Formation of Slit Diaphragm Complex in Glomerular Filtration Barrier. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY[J]. 2021, 32(8): 1946-1960,
Fu, Tao, Zhang, Mingfang, Zhou, Zixuan, Wu, Ping, Peng, Chao, Wang, Yingli, Gong, Xinyu, Li, Ying, Wang, Yaru, Xu, Xiaolong, Li, Miao, Shen, Liqiang, Pan, Lifeng. Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. SCIENCE ADVANCES[J]. 2021, 7(33):
Liu, Guizhen, Fu, Tao, Han, Ying, Hu, Shichen, Zhang, Xuepei, Zheng, Mengmeng, Hao, Piliang, Pan, Lifeng, Kang, Jingwu. Probing Protein-Protein Interactions with Label-Free Mass Spectrometry Quantification in Combination with Affinity Purification by Spin-Tip Affinity Columns. ANALYTICAL CHEMISTRY[J]. 2020, 92(5): 3913-3922, https://www.webofscience.com/wos/woscc/full-record/WOS:000518234700057.
Li, Ying, Cheng, Xiaofang, Li, Miao, Wang, Yingli, Fu, Tao, Zhou, Zixuan, Wang, Yaru, Gong, Xinyu, Xu, Xiaolong, Liu, Jianping, Pan, Lifeng. Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 117(35): 21391-21402, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474698/.
Kangmin Hua, Xiangyang Liu, Yuchun Zhao, Yaojie Gao, Lifeng Pan, Haoran Zhang, Zixin Deng, Ming Jiang. Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis. MBIO[J]. 2020, 11(5): http://dx.doi.org/10.1128/mBio.01334-20.
Qingfei, Zheng, Yukang, Gong, Yujiao, Guo, Zhixiong, Zhao, Zhuhua, Wu, Zixuan, Zhou, Dandan, Chen, 潘李锋, 刘文. 吡咯吲哚霉素生源合成过程中催化反式十氢萘生成的黄素腺嘌呤二核苷酸依赖的4+2环化酶的结构透视. 科学新闻. 2019, 134-134, http://lib.cqvip.com/Qikan/Article/Detail?id=75888869504849574850494951.
Shichen Hu, Yujiao Guo, Yingli Wang, Ying Li, Tao Fu, Zixuan Zhou, Yaru Wang, Jianping Liu, Lifeng Pan. Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering. Nature Communications[J]. 2019, 10(1): 1-12, https://doaj.org/article/945bfe09b3fb4db79823e2b763ce2484.
Pan, Lifeng, Liu, Jianping, Li, Ying, Qin, ZH. Structural Basis of Autophagy Regulatory Proteins. AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE[J]. 2019, 1206: 285-324,
Carrion, Maria Perez, Pischedda, Francesca, Biosa, Alice, Russo, Isabella, Straniero, Letizia, Civiero, Laura, Guida, Marianna, Gloeckner, Christian J, Ticozzi, Nicola, Tiloca, Cinzia, Mariani, Claudio, Pezzoli, Gianni, Duga, Stefano, Pichler, Irene, Pan, Lifeng, Landers, John E, Greggio, Elisa, Hess, Michael W, Goldwurm, Stefano, Piccoli, Giovanni. The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP plus Treatment by Altering LRRK2 Binding to DRP1. FRONTIERS IN MOLECULAR NEUROSCIENCE[J]. 2018, 11: https://www.webofscience.com/wos/woscc/full-record/WOS:000426267500001.
Zheng, Qingfei, Gong, Yukang, Guo, Yujiao, Zhao, Zhixiong, Wu, Zhuhua, Zhou, Zixuan, Chen, Dandan, Pan, Lifeng, Liu, Wen. Structural Insights into a Flavin-Dependent 4+2 Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis. CELL CHEMICAL BIOLOGY[J]. 2018, 25(6): 718-+, http://dx.doi.org/10.1016/j.chembiol.2018.03.007.
Fu, Tao, Liu, Jianping, Wang, Yingli, Xie, Xingqiao, Hu, Shichen, Pan, Lifeng. Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 115(50): E11651-E11660, https://www.webofscience.com/wos/woscc/full-record/WOS:000452866000012.
Xu, Daichao, Jin, Taijie, Zhu, Hong, Chen, Hongbo, Ofengeim, Dimitry, Zou, Chengyu, Mifflin, Lauren, Pan, Lifeng, Amin, Palak, Li, Wanjin, Shan, Bing, Naito, Masanori Gomi, Meng, Huyan, Li, Ying, Pan, Heling, Aron, Liviu, Adiconis, Xian, Levin, Joshua Z, Yankner, Bruce A, Yuan, Junying. TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. CELL[J]. 2018, 174(6): 1477-+, http://dx.doi.org/10.1016/j.cell.2018.07.041.
Li, Faxiang, Xu, Daichao, Wang, Yingli, Zhou, Zixuan, Liu, Jianping, Hu, Shichen, Gong, Yukang, Yuan, Junying, Pan, Lifeng. Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. AUTOPHAGY[J]. 2018, 14(1): 66-79, https://www.webofscience.com/wos/woscc/full-record/WOS:000427049900006.
Maria Perez Carrion, Francesca Pischedda, Alice Biosa, Isabella Russo, Letizia Straniero, Laura Civiero, Marianna Guida, Christian J Gloeckner, Nicola Ticozzi, Cinzia Tiloca, Claudio Mariani, Gianni Pezzoli, Stefano Duga, Irene Pichler, Lifeng Pan, John E Landers, Elisa Greggio, Michael W Hess, Stefano Goldwurm, Giovanni Piccoli. The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1. Frontiers in Molecular Neuroscience[J]. 2018, 11: https://doaj.org/article/966cd6a9f2404d1fad07e6bf77e844ea.
Hu, Shichen, Wang, Yingli, Gong, Yukang, Liu, Jianping, Li, Ying, Pan, Lifeng. Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1. JOURNAL OF MOLECULAR BIOLOGY[J]. 2018, 430(18): 3283-3296, http://dx.doi.org/10.1016/j.jmb.2018.06.030.
Maria Perez Carrion, Francesca Pischedda, Alice Biosa, Isabella Russo, Letizia Straniero, Laura Civiero, Marianna Guida, Christian J Gloeckner, Nicola Ticozzi, Cinzia Tiloca, Claudio Mariani, Gianni Pezzoli, Stefano Duga, Irene Pichler, Lifeng Pan, John E Landers, Elisa Greggio, Michael W Hess, Stefano Goldwurm, Giovanni Piccoli. The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1. FRONTIERS IN MOLECULAR NEUROSCIENCE[J]. 2018, 11: https://doaj.org/article/966cd6a9f2404d1fad07e6bf77e844ea.
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