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Jun-Bin He, Lian Wu, Wanqing Wei, Song Meng, Zheng-Tao Liu, Xuan Wu, Hai-Xue Pan, Sheng Yang, Yong Liang#, Jiahai Zhou#, Gong-Li Tang#. (2023). Enzymatic catalysis favours eight-membered over five-membered ring closure in bicyclomycin biosynthesis. Nat Catal.
Yang, Qin, Zhenkun Zhang, Lin Wang, Xiwen Xing#, Jiahai Zhou#, and Long Li#. (2023). Preparation and Characterization of Metal–Organic Framework Coatings for Improving Protein Crystallization Screening. Nanomaterials, 13(14): 2064.
Dong-Dong Wu, Sheng Jin, Ruo-Xiao Cheng, Wen-Jie Cai#, Wen-Long Xue, Qing-Qing Zhang, Le-Jie Yang, Qi Zhu, Meng-Yao Li, Ge Lin, Yi-Zhen Wang, Xue-Pan Mu, Yu Wang, Igor Ying Zhang, Qi Zhang, Ying Chen, Sheng-Yang Cai, Bo Tan, Ye Li, Yun-Qian Chen, Pu-Juan Zhang, Chen Sun, Yue Yin, Ming-Jie Wang, Yi-Zhun Zhu, Bei-Bei Tao, Jia-Hai Zhou#, Wei-Xue Huang#, and Yi-Chun Zhu#. (2023). Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme. Cell Reports, 42, (7): 112750.
Liu J., Lu J., Zhang C., Zhou Q., Jamieson C.S., Shang C., Houk K.N.#, Zhou J.#, Hu Y.#(2023). Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis. Nat. Chem.
Xu X.#, Yang Q., Wang L., Zheng J., Gu Y., Xing X.#, Zhou J.# (2023) Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening. Catal Sci & Technol, 10.1039/D3CY00366C
Ohashi, M., D. Tan, J. Lu, C. S. Jamieson, D. Kanayama, J. Zhou#, K. N. Houk# and Y. Tang# (2023) Enzymatic cis-decalin formation in natural product biosynthesis. J Am Chem Soc, 145(6): 3301-3305.
Xu, X.#, L. Yang, X. Zhang, X. Xing, J. Zhou# (2023) Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum. Tetrahedron, 130:133174.
Wu P., Y. Gu, L. Liao, Y. Wu, J. Jin, Z. Wang, J. Zhou, S. Shaik#, B. Wang# (2022) Coordination Switch Drives Selective C−S Bond Formation by the Non-heme Sulfoxide Synthases. Angew Chem Int Edit, 61(50): e202214235.
Wang L., X. Zang, J. Zhou (2022) Synthetic biology: A powerful booster for future agriculture. Advanced Agarochem,1(1): 7-11.
Zhang, J., X. Hou, Z. Chen, Y. Ko, M. W. Ruszczycky, Y. Chen, J. Zhou# and H. Liu# (2022) Dioxane bridge formation during the biosynthesis of spectinomycin involves a twitch radical SAM dehydrogenase that may have evolved from an epimerase. J Am Chem Soc, 144(22): 9910-9919.
Huang, X., J. Feng, J. Cui, G. Jiang, W. Harrison, X. Zang, J. Zhou, B. Wang# and H. Zhao# (2022) Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition. Nat Catal, 5: 586–593.
Zhang, X., Z. Xu, J. Zhou, X. Xing# and L. Li# (2022) Enhancement of protein crystallization using nano-sized metal–organic framework. Crystals, 12(5): 578.
Lee, Y., X. Hou, R. Chen, J. Feng, X. Liu, M. W. Ruszczycky, J. Gao#, B. Wang#, J. Zhou# and H. Liu# (2022) Radical S-Adenosyl methionine enzyme BlsE catalyzes a radical-mediated 1,2-diol dehydration during the biosynthesis of Blasticidin S. J Am Chem Soc, 144(10): 4478-4486.
Jin, J., J. Zhou (2022) The mystery of Z-genome biosynthesis has been elucidated. Syn Bio J, 3(1): 1-5.
Chen, T., Z. Zheng, X. Zhang, J. Chen, L. Cha, Y. Tang, Y. Guo#, J. Zhou#, B. Wang#, H. Liu# and W. Chang# (2022) Deciphering the reaction pathway of mononuclear iron enzyme-catalyzed N≡C triple bond formation in isocyanide lipopeptide and polyketide biosynthesis. Acs Catal, 12(4): 2270-2279.
Wu, L., Z. Wang, Y. Cen#, B. Wang# and J. Zhou# (2022) Structural insight into the catalytic mechanism of the endoperoxide synthase FtmOx1. Angew Chem Int Ed Engl, 61(12): e202112063.
Cheng, Q., Y. Cheung, C. Liu, Q. Xiao, B. Sun, J. Zhou, E. W. C. Chan, R. Zhang and S. Chen (2021) Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline. BMC Biol, 19(1): 262.
Wen, W., Y. Zhang, Y. Zhang, Q. Yu, C. Jiang, M. Tang, J. Pu, L. Wu, Y. Zhao, T. Shi, J. Zhou# and G. Tang# (2021) Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12(1): 7085.
Li, S., P. D. Bury, F. Huang, J. Guo, G. Sun, A. Reva, C. Huang, X. Jian, Y. Li, J. Zhou, Z. Deng, F. J. Leeper#, P. F. Leadlay#, M. V. B. Dias# and Y. Sun# (2021) Mechanistic insights into dideoxygenation in gentamicin biosynthesis. Acs Catal, 11(19): 12274-12283.
Xie, L., X. Zang, W. Cheng, Z. Zhang, J. Zhou#, M. Chen# and Y. Tang# (2021) Harzianic acid from Trichoderma afroharzianum is a natural product inhibitor of acetohydroxyacid synthase. J Am Chem Soc, 143(25): 9575-9584.
Xiang, M. Wang, Wu, Z. Lu, J. Tang, J. Zhou, W. Huang#, and G. Zhang# (2021) Structural insights into xylanase mutant 254RL1 for improved activity and lower pH optimum, Enzyme Microb Technol, 147: 109786.
Liu, N., L. Wu, J. Feng, X. Sheng#, J. Li, X. Chen, J. Li, W. Liu, J. Zhou#, Q. Wu#, and D. Zhu# (2021) Crystal structures and catalytic mechanism of L-erythro-3,5-diaminohexanoate dehydrogenase and rational engineering for asymmetric synthesis of β-amino acids, Angew Chem Int Ed, 60: 10203-10.
Gao, D., C. S. Jamieson, G. Wang, Y. Yan, J. Zhou#, K. N. Houk#, and Y. Tang# (2021) A polyketide cyclase that forms medium-ring lactones. J Am Chem Soc, 143: 80-84.
Chen, T., J. Chen, Y. Tang, J. Zhou#, Y. Guo# and W. Chang# (2021) Current understanding toward isonitrile group biosynthesis and mechanism. Chin J Chem, 39(2): 463-472.
Yan, Y., X. Zang, C. S. Jamieson, H. Lin, K. N. Houk, J. Zhou# and Y. Tang# (2020) Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance. Chem Sci, 11(35): 9554-9562.
Ohashi, M., C. S. Jamieson, Y. Cai, D. Tan, D. Kanayama, M. C. Tang, S. M. Anthony, J. V. Chari, J. S. Barber, E. Picazo, T. B. Kakule, S. Cao, N. K. Garg, J. Zhou#, K. N. Houk# and Y. Tang# (2020) An enzymatic Alder-ene reaction. Nature, 586: 64-69.
Chen, C., L. Su#, L. Wu, J. Zhou and J. Wu# (2020) Enhanced the catalytic efficiency and thermostability of maltooligosyltrehalose synthase from Arthrobacter ramosus by directed evolution. Biochem Eng J, 162: 107724.
Cheng, R., L. Wu, R. Lai, C. Peng, N. Naowarojna, W. Hu, X. Li, S. A. Whelan, N. Lee, J. Lopez, C. Zhao, Y. Yong, J. Xue, X. Jiang, M. W. Grinstaff, Z. Deng, J. Chen, Q. Cui#, J. Zhou# and P. Liu# (2020) Single-step replacement of an unreactive C-H bond by a C-S bond using polysulfide as the direct sulfur source in anaerobic ergothioneine biosynthesis. ACS Catal, 10(16): 8981-8994.
Dong, Q., S. Yuan, L. Wu, L. Su, Q. Zhao, J. Wu, W. Huang# and J. Zhou# (2020) Structure-guided engineering of a Thermobifida fusca cutinase for enhanced hydrolysis on natural polyester substrate. Bioresour and Bioprocess, 7(1): 49.
Yang, X., L. Wu, A. Li, L. Ye#, J. Zhou# and H. Yu# (2020) The engineering of decameric D-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions. Chem Commun (Camb), 56(55): 7561-7564.
Li, A., C. G. Acevedo-Rocha, L. D'Amore, J. Chen, Y. Peng, M. Garcia-Borras, C. Gao, J. Zhu, H. Rickerby,S. Osuna#, J. Zhou# and M. T. Reetz# (2020) Regio- and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants. Angew Chem Int Ed Engl, 59(30): 12499-12505.
Chen, T., J. Chen, Y. Tang, J. Zhou#, Y. Guo# and W. Chang# (2020) Pathway from N-alkylglycine to alkylisonitrile catalyzed by Iron (II) and 2-oxoglutarate-dependent oxygenases. Angew Chem Int Ed Engl, 59(19): 7367-7371.
Cai, Y., Y. Hai, M. Ohashi, C. S. Jamieson, M. Garcia-Borras, K. N. Houk#, J. Zhou# and Y. Tang# (2019) Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat Chem, 11(9): 812-820.
Cen, Y., W. Singh, M. Arkin, T. S. Moody, M. Huang, J. Zhou#, Q. Wu# and M. T. Reetz# (2019) Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution. Nat Commun, 10(1): 3198.
Xu, J., Y. Cen, W. Singh, J. Fan, L. Wu, X. Lin, J. Zhou#, M. Huang#, M. T. Reetz# and Q. Wu# (2019) Stereodivergent protein engineering of a lipase to access all possible stereoisomers of chiral esters with two stereocenters. J Am Chem Soc, 141(19): 7934-7945.
Zhou, J., Y. Wang, G. Xu, L. Wu, R. Han, U. Schwaneberg, Y. Rao, Y. L. Zhao, J. Zhou# and Y. Ni# (2018) Structural insight into enantioselective inversion of an alcohol dehydrogenase reveals a "polar gate" in stereorecognition of diaryl ketones. J Am Chem Soc, 140(39): 12645-12654.
Yan, Y., Q. Liu, X. Zang, S. Yuan, U. Bat-Erdene, C. Nguyen, J. Gan, J. Zhou#, S. E. Jacobsen# and Y. Tang# (2018) Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Nature, 559(7714): 415-418.
Li, Y., W. Zhang, H. Zhang, W. Tian, L. Wu, S. Wang, M. Zheng, J. Zhang, C. Sun, Z. Deng, Y. Sun, X. Qu# and J. Zhou# (2018) Structural basis of a broadly selective acyltransferase from the polyketide synthase of splenocin. Angew Chem Int Ed Engl, 57(20): 5823-5827.
Sun, Z., L. Wu, M. Bocola, H. C. S. Chan, R. Lonsdale, X. D. Kong, S. Yuan#, J. Zhou# and M. T. Reetz# (2018) Structural and computational insight into the catalytic mechanism of limonene epoxide hydrolase mutants in stereoselective transformations. J Am Chem Soc, 140(1): 310-318.