个人简介
现为上海中医药大学首席教授、上海中医药大学中药学院院长、磐龙玉矿物药国际研究院院长、创新药物研发上海高校工程中心主任、上海中医药大学附属曙光医院双聘教授。1994年获得日本富山医科药科大学国立和汉药研究所药学博士学位。并于新加坡国立大学化学系及加拿大Dalhousie大学微生物学系进行博士后研究工作。曾先后受聘于香港中文大学中药研究中心科学主任、香港和记黄埔(中国)有限公司副总经理兼高级医药顾问，上海和黄药业有限公司董事兼研究开发总监。2001至2010年,担任香港赛马会中药研究院副总裁兼中药研究室主任。徐教授至今已发表SCI论文270多篇，被SCI源期刊引用9200余次，H指数为54。2014年至今连续入选中国高被引用学者榜。先后主持40余项国家级及国内外企业合作研发项目。获授权美国发眀专利7项，PCT专利1项，中国发明专利30余项，三项中药抗病毒专利及成果成功转让。培养博士后27人，博士及硕士研究生50余人，主编教材及专著5部。先后70余次应邀前往美国、日本、新加坡、马来西亚、葡萄牙、法国、英国、南非、比利时、新西兰、 澳大利亚、韩国、巴西、加拿大、奥地利、印度等国家以及台湾、香港、澳门等地做特邀学术报告或学术会议交流
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Feng J, Xi Z, Jiang X, Li Y, Wan NajbahNik Nabil, Liu MF，Song ZJ，Chen XQ, Zhou H, Dong QH, Xu HX*. Saikosaponin A enhances Docetaxel efficacy by selectively inducing death of dormant prostate cancer cells through excessive autophagy. Cancer letters, 554: 216011. (IF=9.756)
Ren H, Dai R, Chen Y, Xi ZC, Xu HX*. How ginseng regulates autophagy: Insights from multistep process. Biomedicine & Pharmacotherapy, 2023, 158: 114139. (IF=7.419)
Zhang YB, Zhong XL, Xi ZC, Xu HX*. Antiviral Potential of the Genus Panax: An updated review on their effects and underlying mechanism of action. Journal of Ginseng Research, 10.1016/j.jgr.2022.11.003. (IF=5.735)
Liu M, Sun X, Chen B, Dai R, Xi Z, Xu HX*. Insights into Manganese Superoxide Dismutase and Human Diseases. Int J Mol Sci. 2022 Dec 14;23(24):15893. doi: 10.3390/ijms232415893 (IF=6.208)
Liu S, Phang YL, Zheng CW, Xu HX*. Chirality Transfer Strategy in Asymmetric Total Syntheses. Trends in Chemistry, 2022. (2022) (IF=22.448)
Phang YL, Liu S, Zheng CW, Xu HX*. Recent advances in the synthesis of natural products containing the phloroglucinol motif. Nat Prod Rep. 2022 Jun 28. doi: 10.1039/d1np00077b (IF=15.111)
Zhang J, Xu HX, Cho W, Cheuk W, Li Y, Huang QH, Yang W, Xian YF, Lin ZX. Brucein D augments the chemosensitivity of gemcitabine in pancreatic cancer via inhibiting the Nrf2 pathway. J Exp Clin Cancer Res. 2022 Mar 10;41(1):90. (2022) (IF=12.658)
Dai RC, Liu MF, Xiang XC, Xi ZC, Xu HX*. Osteoblasts and osteoclasts: an important switch of tumour cell dormancy during bone metastasis. J Exp Clin Cancer Res. 2022 Oct 28;41(1):316. doi: 10.1186/s13046-022-02520-0. (IF=12.658)
Zhang YL, Chen SM, Yuan M, Xu Y, Xu HX*. Gout and diet: a systemic review of mechanisms and management. Nutrients. 2022. (2022) (IF=6.7)
Tan JQ, Li Z, Chen G, Wu M, Feng JL, Kong SY, Shi XQ, Zhang HM, Lao YZ, Zhou H, Zhang L, Xu HX*. The natural compound from Garcinia bracteata mainly induces GSDME-mediated pyroptosis in esophageal cancer cells. Phytomedicine, 2022. (2022) (IF=6.656)
Xu L, Zhong XL, Xi ZC, Li Y, Xu HX*. Medicinal Compounds against Acyclovir-resistant HSV Infections. Frontiers in Microbiology. 2022. (2022) (IF=6.064)
Zhang J, Xu HX, Dou YX, Huang QH, Xian YF, Lin ZX. Major Constituents From Brucea javanica and Their Pharmacological Actions. Front Pharmacol. 2022 Mar 18;13:853119. (2022) (IF=5.988)
Zheng YN, Zhang WH, Xu L, Zhou H, Yuan M, Xu HX*. Recent Progress in Understanding the Action of Natural Compounds at Novel Therapeutic Drug Targets for the Treatment of Liver Cancer. Front Oncol. 2022 Jan 26; 11:795548. (2022) (IF=5.738)
Chen G, Zhang H, Jiang JM, Chen SM, Zhang GM, Zheng CW, Xu HX*. Metabolomics approach to growth-age discrimination in mountain cultivated ginseng using UPLC-Q-TOF/MS. Journal of Ginseng Research. 2022, under review (2022) (IF= 5.735)
Dai RC, Liu MF, Xiang XC, Li Y, Xi ZC, Xu HX*. OMICS Applications for Medicinal Plants in Gastrointestinal Cancers: Current Advancements and Future Perspectives. Front Pharmacol. 2022 Feb 4; 13:842203. (2022) (IF=5.988)
Zheng ZQ, Tan JQ, Zhang J, Wu M, Chen G, Li Z, Shi XQ, Fu WW,Zhou H, Lao YZ, Zhang L, Xu HX*. The natural compound neobractatin inhibits cell proliferation mainly by regulating theRNA binding protein CELF6. Food & Function, 2022; 13(4):1741-1750. (2022) (IF=6.317)
Song YJ, Yuan M, Xu Y, Xu HX*. Tackling inflammatory bowel diseases: targeting proinflammatory cytokines and lymphocyte homing. Pharmaceuticals. 2022. (2022) (IF=5.2)
Traditional uses, chemical compounds, pharmacological activities and clinical studies on the traditional Chinese prescription Yi-Gan San
Chattarin Ruchawapol, Fu WW and Xu HX*, Antiviral A review on computational approaches of research on TCM against COVID-19. Phytomedicine. 2022 Jul 6;104:154324. doi: 10.1016/j.phymed.2022.154324 (2022) (IF=6.656)
Wan SJ, Ren HG, Jiang JM, Xu G, Xu Y, Chen SM, Chen G, Zheng D, Yuan M, Zhang H, Xu HX*. Two Novel Phenylpropanoid Trimers from Ligusticum chuanxiong Hort With Inhibitory Activities on Alpha-Hemolysin Secreted by Staphylococcus aureus. Frontiers in Chemistry, 2022; Vol. 10 (2022) (IF=5.545)
Phang YL, Zheng CW, Xu HX*. Structural diversity and biological activities of caged Garcinia xanthones: recent updates. Acta Materia Medica. Vol. 1(1):72-95.
Li H, Wei WY, Xu HX*. Drug discovery is an eternal challenge for the biomedical sciences. Acta Materia Medica. Vol. 1(1):1-3.
Nik Nabil WN, Xi ZC, Liu MF, Li Y, Yao M, Liu T, Dong QH, Xu HX*. Advances in therapeutic agents targeting quiescent cancer cells. Acta Materia Medica. Vol. 1(1):56-71.
Shi XQ, Chen G, Tan JQ, Li Z, Chen SM, He JH, Zhang L, Xu HX*. Total Alkaloids fraction of Leonurus japonicus Houtt. promotes angiogenesis and wound healing through SRC/MEK/ERK signaling pathway. Journal of Ethnopharmacology, 2022, under review (2022) (IF=5.195)
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