姚祝军 - 中国科学院上海有机化学研究所 - 生命有机化学国家重点实验室

研究领域

生理活性天然产物全合成、类天然产物化学与化学生物学; 活细胞内分子事件的可视化研究传统药物化学成分的药物化学研究

近期论文

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Liu, G.-S.; Dong, Q.-L.; Yao, Y.-S.; Yao, Z.-J.* Expeditious Total Syntheses of Camptothecin and 10-Hydroxycamptothecin. Organic Letters 2008, 10(23), 5393-5396. Chen, L.; Li, F.-Q.; Hou, B.-H.; Hong, G.-F.;* Yao, Z.-J.* Site-Specific Fluorescent Labeling Approaches for Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling Pathways. J. Org. Chem. 2008, 73(21), 8279-8285. Liu, H.-X.; Shao, F.; Li, G.-Q.; Xun, G.-L.; Yao, Z.-J.* Tuning the Acyclic Ether Moiety of Anticancer Agent AA005 with Conformation-Constrained Fragments. Chem. Eur. J. 2008, 14(28), 8632-8639. Yao, Y.-S.; Yao, Z.-J.* Biomimetic Total Synthses of Cassiarins A and B. J. Org. Chem. 2008, 73(14), 5221-5225. Zhou, H.-B.; Liu, G.-S.; Yao, Z.-J.* Short and Efficient Total Synthesis of Luotonin A and 22-Hydroxyacuminatine Using A Common Cascade Strategy. J. Org. Chem. 2007, 72(16), 6270-6272. Qian, W.-J.; Wei, W.-G.; Zhang, Y.-X.; Yao, Z.-J.* Total Synthesis, Assignment of Absolute Chemistry and Structure Revision of Chlorofusin. J. Am. Chem. Soc. 2007, 129, 6400-6401. Zhou, H.-B.; Liu, G.-S.; Yao, Z.-J.* Mild Cascade Reactions Triggered by Bis(triphenyl)oxodiphosphonium Trifluoromethanesulfonate and A Concise Total Synthesis of Camptothecin. Organic Letters 2007, 9, 2003-2006. Liu, H.-X.; Huang, G.-R.; Zhang, H.-M.; Jiang, S.; Wu, J.-R.;* Yao, Z.-J.* A Structure-Activity Guided Strategy for Fluorescent Labeling of Annonaceous Acetogenin Mimetics and Its Application in Cell Biology. ChemBioChem 2007, 8(2), 172-177. Hong, W.-X.; Chen, L.-J.; Zhong, C.-L.; Yao, Z.-J.* Bi-directional Synthesis of the Central Amino Acid of Chloptosin. Organic Letters 2006, 8(21), 4919-4922. Cong, X.; Yao, Z.-J.* RCM-Based Synthesis of (3R,4R,5S)-4-Acetylamino-5-amino-3-hydroxy- cyclohex-1-ene-carboxylic Acid Ethyl Ester, A Functionalized Cycloalkene Skeleton of GS4104. J. Org. Chem. 2006, 71(14), 5365-5368. Wei, W.-G.,Yao,Z.-J.* Synthesis Studies Toward Chloroazaphilone and Vinylogous -Pyridones: Two Common Natural Product Core Structures. J. Org. Chem. 2005, 70(12), 4585-4590. Cong, X., Hu, F., Liu, K.-G., Liao, Q.-J., Yao, Z.-J.* Chemoselective Deprotection of Cyclic N,O-Aminals Using Catalytic Bismuth(III) Bromide in Acetonitrile. J. Org. Chem. 2005, 70(11), 4514-4516. Cong, X., Liao, Q.-J., and Yao, Z.-J.* RCM Approaches Toward the Diastereoselective Synthesis of Vicinal trans-Diaminocyclitols from L-Serine. J. Org. Chem. 2004, 69, 5314-5321. Wen, S.-J., Yao. Z.-J.* Total Synthesis of Cyclomarin C. Organic Letters 2004, 6, 2721-2724. Liu, K.-G., Yan, S., Wu, Y.-L., Yao, Z.-J.* Synthesis of 4-Azido-4-deoxy-Neu5,7,8,9Ac4- 2en1Me, A Key Intermediate for the Synthesis of GG167 from D-Glucono-d-lactone. Organic Letters 2004, 6(13), 2269-2272. Jiang, S., Li, Y., Chen, X.-G., Hu, T.-S., Wu, Y.-L., and Yao, Z.-J.*, Parallel Fragment Assembly Strategy Towards Multi-ether Mimicry of Anti-cancer Annonaceous Acetogenins. Angew. Chem. Int. Ed. 2004, 43(3), 329-334.