个人简介
一、个人简介
袁哲明,男,1971年9月出生。2000年6月获浙江大学博士学位。教授,博士生导师,生物信息学博士点领衔人,农业大数据分析与决策湖南省工程技术研究中心主任。二、教育背景
1996/09–2000/06浙江大学,农业与生物技术学院植物保护专业,博研毕业,博士;
1992/09–1995/06湖南农业大学,植物保护学院昆虫专业,研究生毕业,硕士;
1988/09–1992/07湖南师范大学大学,生命科学学院生物专业,本科毕业,学士。
三、成果介绍
1.主持的主要科研项目
[1]粘虫痘病毒增效基因的克隆、表达及其应用.国家自然科学基金.2002.01-2004.12,批准号:30100122
[2]发泡聚苯乙烯的大生物降解研究.国家自然科学基金.2006.01-2008.12,批准号:30570351
[3]生物信息学新算法.教育部新世纪优秀人才支持计划项目,2006年入选,批准号:NCET-06-0710
[4]含冰核基因的促冻重组病毒构建及其应用.湖南省杰出青年基金,2010.01-2012.12,批准号:10jj1005
[5]基于均匀设计和支持向量回归的配方优化试验设计与分析.教育部高等学校博士点专项基金(博导类),2009.1-2011.12,批准号:200805370002
[6]高活性抗菌肽的分子设计与合成.教育部博士点基金(博导类),2013.1-2015.12,批准号:20124320110002。
3.主要获奖成果
主持获湖南省自然科学三等奖一项,参与获国家科技进步二等奖、教育部科技进步二等奖、湖南省科技进步三等奖各一项。
4.其它重要成果
被评为校首届十佳研究生导师。指导研究生获省优硕士论文4篇、校优博士论文3篇、校优硕士论文6篇;获全国研究生数模竞赛二等奖2项、三等奖2项,省研究生数模竞赛一等奖一项、三等奖2项。
近期论文
查看导师新发文章
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[1]XingPengwei;YuanChen;JunGao;LianyangBai;ZhemingYuan*.Afastapproachtodetectgene-genesynergy,ScientificReports,2017.11.27,7(16437)
[2]ChenYuan;CaoDan;GaoJun;ZhemingYuan*.Discoveringpair-wiseSynergiesinMicroarrayData,ScientificReports,2016.6,30672
[3]ChenYuan;WangLifeng;LiLanzhi;ZhangHongyan;ZhemingYuan*.Informativegeneselectionandthedirectclassificationoftumorsbasedonrelativesimplicity,BMCBioinformatics,2016.1.19,17(44):1~16
[4]DaiZhijun;WangLifeng;ChenYuan;WangHaiyan;BaiLianyang;ZhemingYuan*.ApipelineforimprovedQSARanalysisofpeptides:physiochemicalpropertyparameterselectionviaBMSF,near-neighborsampleselectionviasemivariogram,andweightedSVRregressionandprediction,Aminoacids,2014.04.1,46(4):1105~1119
[5]Zhang,Hongyan;Wang,Haiyan;Dai,Zhijun;Chen,Ming-shun;Yuan,Zheming*.Improvingaccuracyforcancerclassificationwithanewalgorithmforgenesselection,BMCBioinformatics,2012.11.13,13(298):1~20
[6]Wang,Haiyan;Zhang,Hongyan;Dai,Zhijun;Chen,Ming-shun;Yuan,Zheming*.TSG:anewalgorithmforbinaryandmulti-classcancerclassificationandinformativegenesselection,BMCMedicalGenomics,2013.1.23,6
[7]ChenYuan;ZengYing;LuoFeng;Yuan,Zheming*.ANewAlgorithmtoOptimizeMaximalInformationCoefficient,PLoSONE,2016,11(6)
[8]LifengWang;ZhijunDai;HongyanZhang;LianyangBai;ZhemingYuan*.QuantitativeSequence–ActivityModelAnalysisofOligopeptidesCouplinganImprovedHigh-DimensionFeatureSelectionMethodwithSupportVectorRegression,ChemBiolDrugDes,2014.1.1,83:379~391
[9]Zhou,Wei;Dai,Zhijun;Chen,Yuan;Wang,Haiyan;Yuan,Zheming*.High-DimensionalDescriptorSelectionandComputationalQSARModelingfor
AntitumorActivityofARC-111AnaloguesBasedonSupportVectorRegression
(SVR),InternationalJournalofMolecularSciences,2012.1,13(1):1161~1172
[10]ZhangHongyan;LiLanzhi;LuoChao;SunCongwei;ChenYuan;DaiZhijun;YuanZheming*.Informativegeneselectionanddirectclassificationoftumorbasedonchi-squaretestofpairwisegeneinteractions,BioMedResearchInternational,2014.7.1,2014
[11]LiJinliang;WangLifeng;WangHaiyan;BaiLianyang;YuanZheming*.High-AccuracySpliceSitesPredictionBasedonSequenceComponentandPositionFeatures,GeneticsandMolecularResearch,2012,11(3):3432~3451
[12]ChenYuan;ZhouWei;WangHongyan;YuanZheming*.PredictionofO-glycosylationsitesbasedonmulti-scalecompositionofaminoacidsandfeatureselection,Medical&BiologicalEngineering&Computing,2015,53(6):535~544
[13]ZhouWei;WuShubo;DaiZhijun;ChenYuan;XiangYan;ChenJianrong;SunChunyu;ZhouQingming;YuanZheming*.NonlinearQSARmodelswithhigh-dimensionaldescriptorselectionandSVRimprovetoxicitypredictionandevaluationofphenolsonphotobacteriumphosphoreum,ChemometricsandIntelligentLaboratorySystems,2015,145:30~38
[14]XiangYan,ChenYuan,TanSiqiao,YuanZheming*.PredictingO-glycosylationSitesbyCombiningThreeDifferentTypesofFeatures.ProgressinBiochemistryandBiophysics,2016,43(7):1~8
[15]WeiZhou;YanjunFan;XunhuiCai;YanXiang;PengJiang;ZhijunDai;YuanChen;SiqiaoTan;ZhemingYuan*.High-accuracyQSARmodelsofnarcosisoxicitiesofphenolsbasedonvariousdatapartition,descriptorselectionandmodellingmethods,RSCAdvance,2016.10.02,6:106847~106855
学术兼职
湖南省生物信息学会副理事长,中国昆虫学会昆虫基因组专门委员会委员。