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个人简介

二级教授、主任医师、德国医学博士、博士生导师。现任暨南大学第一临床医学院(附属第一医院)院长,暨南大学附属第一医院脑血管病中心主任,暨南大学临床医学研究院院长,暨南大学临床神经科学研究所所长。

研究领域

神经病学特别是脑血管病的临床、教学和科研工作,重点缺血性脑血管病预防和治疗,神经胶质细胞与神经元相互反应,经颅多普勒超声诊断临床应用

近期论文

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Xu AD(通讯作者),Wang YJ,Wang D, on behalf of Chinese Stroke Therapy Expert Panel for Intravenous Recombinant Tissue Plasminogen Activator. Consensus Statement on the Use of Intravenous Recombinant Tissue Plasminogen Activator to Treat Acute Ischemic Stroke by the Chinese Stroke Therapy Expert Panel. CNS NeurosciTher, 2013, 19(8):543-548.A1 Zhao Y, Xu AD(共同通讯作者),et al. Changes in the retinal morphology, electroretinogram and visual behavior after transient global ischemia in adult rats. Plos One, 2013, 8(6):e65555. Wang YJ, Xu AD(第12),et al,for the CHANCE investigators. Clopidogrel and Aspirin versus Aspirin Alone for Acute TIA and Minor Stroke. N Engl J Med. 2013, 369(1):11-19. 徐安定(执笔专家之一). 缺血性卒中侧支循环评估与干预中国专家共识. 中国卒中杂志 2013;8(4):285-293. Dong DW, Xu AD(通讯作者), et al. Ischemia induces hyperphosphorylation of tau protein in the ipsilateral thalamus after focal cortical infarction in rats. Brain Res. 2014,16;1543:280-289. A2 Bi W, Zhu L, Zeng Z, Jing X, Liang Y, Guo L, Shi Q, Xu A(共同通讯), Tao E.Investigations into the Role of 26S Proteasome Non-ATPase Regulatory Subunit 13 in Neuroinflammation. Neuroimmunomodulation. 2014;21(6):331-7 A2 徐安定,丁燕,李牧. 中国缺血性卒中早期静脉溶栓的现状、阻碍因素及改进策略. 中国卒中杂志,2014,9(6):553-560. Huang LA, Ling XY, Li C, Zhang SJ, Chi GB, Xu AD(通讯作者).Study of white matter at the centrum semiovale level with magnetic resonance spectroscopy and diffusion tensor imaging in cerebral small vessel disease. Genet Mol Res. 2014 Apr 8;13(2):2683-90. doi: 10.4238/2014.April.8.11. A2 国家卫生和计划生育委员会脑卒中医疗质量控制中心,中华预防医学会卒中预防与控制专业委员会,(通讯作者徐安定). 2014缺血性卒中/短暂性脑缺血发作患者合并心房颤动的筛查及抗栓治疗中国专家共识. 中华内科杂志,2014,53(8):665-667. Shi L, Li B, Huang Y, Ling X, Liu T, Lyon GJ, Xu A(共同通讯作者), Wang K."Genotype-first" approaches on a curious case of idiopathic progressive cognitive decline.BMC Med Genomics. 2014 Dec 3;7:66. doi: 10.1186/s12920-014-0066-9. A1 Jing Z, Zhang S, Tang J, Xu A, Ruan Y, Huang L.Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis.Clin Case Rep. 2014 Jun;2(3):70-3. doi: 10.1002/ccr3.60. Epub 2014 Mar 16. Liu LB,Li M,Zhuo WY,Zhang YS, Xu AD(通讯作者). The Role of Hs-CRP, D-Dimer and Fibrinogenin Differentiating Etiological Subtypes of Ischemic Stroke. PLoS One. 2015 Feb 13;10(2):e0118301. doi: 10.1371/journal.pone.0118301. eCollection 2015. IF 3.243 A2 Li M, Wang-Qin RQ, Wang YL, Liu LB, Pan YS, Liao XL, Wang YJ, Xu AD(通讯作者).Symptomatic Intracerebral Hemorrhage after Intravenous Thrombolysis in Chinese Patients: Comparison of Prediction Models. J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1235-1243 IF 1.67 Lu D, Xu A(共同第一,第一为本人博士), Mai H, Zhao J, Zhang C, Qi R, Wang H, Lu D, Zhu L. The synergistic effects of heat shock protein 70 and ginsenoside Rg1 against tert-butyl hydroperoxide damage model in vitro. Oxid Med Cell Longev. 2015;2015:437127. doi: 10.1155/2015/437127. Epub 2015 Jan 15. IF 3.516 A2 Yang ZH, Cai X, Xu A(通讯作者), et al. Bone marrow stromal cell transplantation through tail vein injection promotes angiogenesis and vascular endothelial growth factor expression in cerebral infarct area in rats. Cytotherapy, 2015; 17: 1200-1212. IF 3.3 A2 Gui J, Guo J, Nong F, Jiang D, Xu A, Yang F, Chen Q, Lin Y.Impact of individual characteristics on sonographic IVC diameter and the IVC diameter/aorta diameter index.Am J Emerg Med. 2015;33(11):1602-5. IF 1.27 中国卒中学会,中国卒中学会神经介入分会,中华预防医学会卒中预防与控制专业委员会介入学组. 急性缺血性卒中血管内治疗中国指南, 中国卒中杂志,2015,10(7):590-561. (徐安定执笔专家) Lu D and Xu AD(通讯作者). Mini Review: Circular RNAs as Potential Clinical Biomarkers for Disorders in the Central Nervous System. Front Genet. 2016:7:53.doi: 10.3389/fgene.2016.00053 Zhu H, Zhang Y, Shi Z, Lu D, Li T, Ding Y, Ruan Y2 Xu A(通讯作者). The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways. Sci Rep. 2016 May 31;6:26859. doi: 10.1038/srep26859. Cheng JH, Ye Q, Ye ZS, Li ZQ, Xu AD(通讯作者).Five-year experience of 101 adult patients with moyamoya disease at a single institution in Eastern China. J Cli Neurosci. 2016,32:30–34.

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