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研究领域

天然产物化学,天然药物化学,有机合成化学。

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Vermistatin Derivatives with α-Glucosidase Inhibitory Activity from the Mangrove Endophytic Fungus Penicillium sp. HN29-3B1, Planta Med., 2014, 80, 912-917. Sulfur-Containing Benzofurans from a Soft Coral-Derived Fungus Eurotium rubrum SH-823 , Mar. Drugs, 2014, 12, 3669-3680. Alterporriol-Type Dimers from the Mangrove Endophytic Fungus, Alternaria sp. (SK11), and Their MptpB Inhibitions, Mar. Drugs, 2014, 12, 2953-2969. A New Polyketide from the Mangrove Endophytic Fungus Penicillium sp. sk14JW2P,Helv. Chim. Acta,2014, 97, 664-668 Peniphenones A–D from the Mangrove Fungus Penicillium dipodomyicola HN4-3A as Inhibitors of Mycobacterium Tuberculosis Phosphatase (MptpB), J. Nat. Prod. 2014, 77, 800−806. Xylanthraquinone, a new anthraquinone from the fungus Xylaria sp. 2508 from the South China Sea,Nat. Prod. Res., 2014, 28(2), 111-114. Asperterpenols A and B, New Sesterterpenoids Isolated from a Mangrove Endophytic Fungus Aspergillus sp. 085242 , Org. Lett., 2013,15(10), 2522-2525. Asperterpenoid A, a New Sesterterpenoid as an Inhibitor of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B from the Culture of Aspergillus sp. 16-5c, Org. Lett. 2013,15(4), 721-723. Structure and Absolute Configuration of Fumiquinazoline L, an Alkaloid from a Gorgonian-Derived Scopulariopsis sp. Fungus, J. Nat. Prod. 2013, 76(4), 779-782. Bioactive indole alkaloids and phenyl ether derivatives from a marine-derived Aspergillus sp. fungus,J. Nat. Prod. 2013, 76(4), 547-553. New Dimeric Members of the Phomoxanthone Family: Phomolactonexanthones A, B and Deacetylphomoxanthone C Isolated from the Fungus Phomopsis sp. Mar. Drugs, 2013, 11, 4961-4972. A New Anti-acetylcholinesterase alpha-Pyrone Meroterpene, Arigsugacin I, from Mangrove Endophytic Fungus Penicillium sp sk5GW1L of Kandelia candel, Planta Med., 2013, 79(16) ,1572-1575. A Novel Marine Drug, SZ-685C, Induces Apoptosis of MMQ Pituitary Tumor Cells by Downregulating miR-200c. Curr. Med. Chem. 2013, 20(16):2145-54. Studies on the Synthesis of Derivatives of Marine-Derived Bostrycin and Their Structure-Activity Relationship against Tumor Cells, Mar. Drugs, 2012, 10, 932-952. Synthesis and Antitumor Activities of Derivatives of the Marine Mangrove Fungal Metabolite Deoxybostrycin, Mar. Drugs,2012, 10, 2715-2728. Synthesis of Trisubstituted Isoxazoles by Palladium(II)-Catalyzed Cascade Cyclization-Alkenylation of 2-Alkyn-1-one O-Methyl Oximes, J. Org. Chem., 2012, 77(7), 3627-3633. Bioactive Hydroanthraquinones and Anthraquinone Dimers from a Soft Coral-Derived Alternaria sp. Fungus, J. Nat. Prod. 2012, 75(2), 189-197. Antibacterial anthraquinone derivatives from a sea anemone-derived fungus Nigrospora sp. J. Nat. Prod. 2012, 75(5), 935-941.

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