研究领域
有机合成化学。
1. 生物活性有机磷化合物的设计与合成；
2. 天然产物结构改造；
3. 发展有机合成新反应。
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Peng AY,* Du Y, Wei Y , Xie L, Ding YX. Acid/base-catalyzed cyclization of O-alkynylphenylphosphonic acid monoesters and (O-hydroxyphenyl)ethynyl- phosphinates, Heteroatom Chem. 2011, 22, 649.
Peng AY,* Chen BT, Wang Z, Wang B, Mo XB, Wang YY, Chen PJ. Pd(0)/iodide salt-mediated Heck reaction of aryl nonaflates: Application to the synthesis of 2-(1-alkenyl)phenylphosphonates, J. Fluorine Chem. 2011, 132, 982.
Peng G, Du Y, Wei Y, Tang J, Peng AY,* Rao L. “A new synthesis of fully phosphorylated flavones as potent pancreatic cholesterol esterase inhibitors”, Org. Biomol. Chem., 2011, 9, 2530.
Baojian Li, Binhua Zhou, Hailiang Lu, Lin Ma, Ai-Yun Peng*, “Phosphaisocoumarins as a new class of potent inhibitors for pancreatic cholesterol esterase”, Eur. J. Med. Chem. 2010, 45, 1955-1963.
Ai-Yun Peng,* Fei Hao, Baojian Li, Zheng Wang, Yidan Du, “An Efficient Route to 4-Halophosphaisocoumarins via CuX2-Mediated Direct Halocyclization of 2-(1-Alkynyl)phenylphosphonic Acid Diesters”, J. Org. Chem. 2008, 73, 9012-9015.
Ai-Yun Peng,* Yu-Juan Guo, Zhi-Hai Ke, Shizheng Zhu, “Alcoholysis of Phosphaisocoumarins and Synthesis of 2-(2-Oxo-alkyl)phenyl- phosphonates”, Eur. J. Org. Chem. 2008, 5277-5282.
Ai-Yun Peng,* Baojian Li, Xun Yang, Junying Lin, “Synthesis of Phosphaisocoumarin Acids via Me3SiX-Mediated Dealkylation Reaction”, Synthesis, 2008,2412-2416.
Ai-Yun Peng,* Xun Yang, Bo Wang, “Synthesis and reactions of phosphaisocoumarins”, Phosphorus, Sulfur, Silicon, and Related Elements, 2008, 183, 665-666.
Ai-Yun Peng, Yi-Xiang Ding*. “Synthesis of 2H-1,2-Oxaphosphorin 2-Oxides via Ag2CO3-Catalyzed Cyclization of (Z)-2-Alken-4-ynylphosphonic Monoesters”, Org. Lett. 2005, 7, 3299-3301.
Ai-Yun Peng, Yi-Xiang Ding*. “Synthesis of 4-halophosphaisocoumarins via halocyclization of 2-(1-alkynyl)phenylphosphonates”, Tetrahedran 2005, 61, 10303-10308.
Ai-Yun Peng, Xin-Ying Zhang, Yi-Xiang Ding*. “A Convenient and Applicable Route to Synthesize 2-(1-Alkynyl)phenylphosphonates”, Heteroatom Chem. 2005, 16, 529-534.
Ai-Yun Peng, Yi-Xiang Ding*. “Synthesis of Phosphaisocoumarins via Iodocyclization”, Org. Lett. 2004, 6, 1119-1121.
Ai-Yun Peng, Yi-Xiang Ding*. “The Synthesis of Phosphaisocoumarins by Cu(I)-Catalyzed Intramolecular Cyclization of o-Ethynylphenylphosphonic Acid Monoesters”, J. Am. Chem. Soc.2003, 125, 15006-15007.
Ai-Yun Peng, Yi-Xiang Ding*. “Mercury(II)-Catalyzed Regioselective Addition Reaction of Monoesters of Phosphonic Acid to Terminal Alkynes: Synthesis of Vinyl Phosphonates”,Synthesis2003, 205-208.
彭爱云,郭御卷,王正,李保健,杜一丹, “膦异香豆素酰胺及其合成方法与应用”, 中国专利, CN 101367840A, 2009.
彭爱云,李保健,郭御卷, “膦异香豆素盐及其制备方法”, 中国专利,CN 101143880, 2008.
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