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化学生物学,酶学及其应用。目前主要从事酪氨酸酶、葡萄糖苷酶、乙酰胆碱酯酶等酶抑制剂的设计合成及活性筛选,筹建化学生物学实验室(化学微生物学实验室、化学遗传学实验室和组合合成实验室),进行化合物对细胞功能的调控研究。 酶抑制剂的设计合成,化妆品功能材料的合成,有机合成中的生物转化

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L. Ma, S.G.Cao, B.X.Yan, et al,. Induce Rebuliding of Conformetion of Aspartase, Ann. N. Y. Acad. Sci., 672, 62-67, 1992. S.GCao , L.Ma, Feng Y, et al, Improvement of Enzymatic Properties by Hydrophobic Interaction. Bioche-mical Engineering. 100-102, 1992.  S.G Cao ,Y .Feng , L. Ma, et al,.A Study on Increasing Enzymatic Stability and Activity in Organic Solvents. Ann.N.Y. Acad.Sci. ,627:152,1992. S.G Cao , Z.B. Liu , Y. Feng , L.Ma, et al,. Esterification and Transesterifacation With Immobilized Lipase in Organic Solvent. Applied Biochem and Biotech., 32:1-6,1992.  Y.G. Ma, J.G.Tang, L.Ma S.Y.Liu et al,. Photoluminescence and Electroluminescence of Poly p-Phenyl Phenol Prepared by Enzymitic Catalyzed Polymerization. Chin. Phys.Lett, 11(6), 387, 1994.  H.Yang, S.G.Cao, L.Ma et al,.A New Kind of Immobilized Lipase in Organic Solvent and Its Structure Model. Biochemical and Biophysical Communitions. 200(1):83, 1994. L.Ma, Z.J.Li, Y.H.Cheng, J.C.Shen。Regulation of Lactate Dehydrogenase Activity by Synthetic Polycations.Ann. N. Y. Acad. Sci. ,750, 75, 1995.  L.Ma, B.X.Yan, H.T.Zou, et al,.Alteration of Specificity in L-Aspartase in the Presence of Alcohol. Ann. N. Y. Acad. Sci.1995. 750, 134. W.Liu, L.Ma, J.D, Wang, et al,. Effect of Aggregation of p-Phenylphenol on Enzymatic Polymer Synthesis in Dioxane/Water Mixture J.Polymer Science: Part A: Polymer Chemistry.33, 2339-2345, 1995.  W. Liu , J.D.Wang, L. Ma, et al., Enzymatic Polymerization of p-Phenylphenol in Aqueous Micells . Ann.N.Y. Acad. Sci.750, 138,1995. S.G.Cao, S.D. Liu, L. Ma , et al. Studies on a New Type of Immobilized Lipase Fitting in Organic Solvents. Ann.N.Y.Acad.Sci .750, 222, 1995. L.Ma X.T.Wang, X.Tang et al,.《Immobilization of Prostaglandin Synthetase by Hydrophobic Adsorption》 56, 223,1996. Appied Biochem. Biotechnol. W. Liu, L. Ma, X.D.Sun, et al.,《Fluorometric Assays for Horseradish Peroxidase in Non aqueous Media》56, 1996.Applied Biochem and Biotechol. Y.X. Shi, Y.M. Jing, D.X.Sui, Y.L.Li, T.Chen, L.Ma, Z.T.Ding《Affinity Chromatography of Trypsin Using Chitosan as Ligand Support》J. Chro-matography A. 742, 107, 1996. Cao-SG, Yang-H , Ma-L, Guo-SQ .《Enhancing Enzymatic-Properties by the Immobilization Method》Applied biochem.biotech 1996, Vol 59, Iss 1, 7-14。  Wang,S.G, Liu W, Ji X.S, Ma L, et al.《Stopped-flow pre-steady-state kinetic study of horeseradish prooxidase catalysis in nonaqueous media》Ann.N.Y.Acad.Sci 799,364,1996. Gu L.Q, Wei H.F, Zhang X.C, Xu G, Ma L.《Bio reduction of quinone derivatives by immobilized Baker’s Yeast in hexane》Chinese J. Chemistry, 16(1-4)1998. D.L.Liu, L.Ma.《Armillariella tabescen Enzymatic detoxification of Afatoxin B1 Part III: Immobilized enzymatic detoxifacation》Ann.N.Y.Acad.Sci 864, 592-599,1998.  D.L.Liu, D.S.Yao, L.Q.Gu, L.Ma,《Armillariella tabescen Enzymatic detoxification of Afatoxin B1 Part II》Ann.N.Y.Acad Sci, 864, 586-591,1998. D.S.Yao, D.L.Liu,R.Liang,L.Q.Gu, L.Ma,《Screening of the Fungus whose Multienzyme system Has Detoxification Activity towards Aflatoxin B1》Ann.N.Y.Acad.Sci 864, 579-585,1998.

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