宋相志 - 中南大学 - 化学化工学院

个人简介

宋相志，二级教授，教育部“新世纪优秀人才计划”获得者，中南大学“升华学者”特聘教授，博士生导师，中南大学化学化工学院副院长。 2002年在北京大学获得博士学位，2003-2005年在哈佛大学从事博士后研究，2005-2009年担任哈佛大学Senior Scientist，2009年聘为中南大学“升华学者”特聘教授。工作经历 2009.9-至今中南大学化学化工学院副院长教授 2005.3-2009.8 哈佛大学 Rowland Institute Senior Scientist 2003.3-2005.2 哈佛大学 Rowland Institute 博士后

研究领域

[1] 抗癌光疗药物 [2] 分子荧光探针 [3] 荧光染料的设计与合成

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Auxochrome dimethyldihydroacridine improves fluorophores for prolonged live-cell super-resolution imaging.Journal of the American Chemical Society, 2024 Coumarin-based two-photon AIE fluorophores: Photophysical properties and biological application.Chinese Chemical Letters, 2023, 34 (4) : 107674. Three birds one stone: an enzyme-activatable theragnostic agent for fluorescence diagnosis, photodynamic and inhibitor therapies.Chemical Communication, 2023, 59 (31) : 4676-4679. Copper coordination-based conjugated polymer nanoparticles for synergistic photodynamic and chemodynamic therapy.Chemical Communication, 2023, 59 (42) : 5464-5467. An estradiol-functionalized red-emissive photosensitizer for enhanced and precise photodynamic therapy of breast cancers.Chemical Communication, 2023, 59 (46) : 7060-7063. Vascular disruption agent and phototherapeutic assembled nanoparticles for enhanced tumor inhibition.Chemical Communication, 2023, 59 (65) : 9896-9899. Carbon Monoxide: A Second Biomarker to Couple with Viscosity for the Construction of “Dual-Locked” Near-Infrared Fluorescent Probes for Accurately Diagnosing Non-Alcoholic Fatty Liver Disease.Analytical Chemistry, 2023, 95: 18619-18628. Construction of a Dual-Functional, Reversible, Ratiometric, GolgiTargeting Fluorescent Probe for Real-time Monitoring of Dynamics of Intracellular Redox Homeostasis.Analytical Chemistry, 2023, 95: 8002-8010. Accurate diagnosis of hepatic ffbrosis with dual detection of nitric oxide and viscosity by a ratiometric ffuorescent probe.Chemical Engineering Journal, 2023, 463: 142383. A robust dual-channel fluorescence-enhanced probe for duplex imaging of endogenous HClO/ClO- in living cells and in zebrafish[J].Sens. Actuator B: Chem., 2022, 359: 131562. Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer[J].J. Phys. Chem. Lett., 2022, 13: 7939-7946. A ratiometric fluorescent probe with large Stokes shift and emission shift for sensing hydrazine in living organisms[J].Spectrochim. Acta A Mol. Biomol. Spectrosc., 2022, 274: 121096. Tumor microenvironment-responsive S-NSs-TPZ-ICG intelligent nanoplatforms for synergistically enhanced tumor multimodal therapy[J].Chem. Commun., 2022, 58: 6251-6254. Evaluation of Nitric Oxide Fluctuation Via a Fast, Responsive Fluorescent Probe in Idiopathic Pulmonary Fibrosis Cells and Mice Models[J].Anal. Chem., 2022, 94: 4072-4077. Rational Development of Dual-Ratiometric Fluorescent Probes for Distinguishing between H2S and SO2 in Living Organisms[J].Anal. Chem., 2021, 93 (45) : 15209-15215. Improved synthetic method of Benzo[a]pheno-selenazinium phototherapeutic agents[J].Dyes Pigm., 2021, 188: 109154. A Ratiometric, Fast-Responsive, and Single-Wavelength Excited Fluorescent Probe for the Discrimination of Cys and Hcy[J].Anal. Chem., 2021, 93: 10934-10939. A red-emitting fluorescent probe for sensing and imaging biothiols in living cells[J].J. Lumin., 2021, 234: 117994. Rational design of a bifunctional fluorescent probe for distinguishing Hcy/Cys from GSH with ideal properties[J].Chin. Chem. Lett., 2021, 32: 1061-1065. Selective and discriminative fluorescence sensing of Cys, Hcy, GSH and H2S with concise and distinct signals[J].Sens. Actuator B: Chem., 2021, 331: 129394. Tackling the Selectivity Dilemma of Benzopyrylium–Coumarin Dyes in Fluorescence Sensing of HClO and SO2[J].Anal. Chem., 2021, 93: 5194-5200. Investigation of the Relationship Between H2O2 and HClO in Living Cells by a Bifunctional, Dual-ratiometric Responsive Fluorescent Probe[J].Anal. Chem., 2020, 92: 5134-5142. Fluorescent Detection of Dynamic H2O2/H2S Redox Event in Living Cells and Organisms[J].Anal. Chem., 2020, 92: 4387-4394. Carbon dots and CdTe QDs hybrid-based fluorometric probe for spermine detection.Dyes Pigm., 2020: 10.1021/acs.iecr.9b0. Red-emitting boron difluoride complexes with a mega-large Stokes shift and unexpectedly high fluorescence quantum yield[J].Chem. Commun., 2020, 56: 2159-2162. A carbon dots-based fluorescent probe for turn-on sensing of ampicillin[J].Dyes Pigm., 2020: 10.1016/j.dyepig.201. Red-Emitting Fluorescent Probe for Discrimination of Cys/Hcy and GSH with A Large Stokes Shift under A Single-Wavelength Excitation[J].New J. Chem., 2020, 1097: 245-253. A rapid and sensitive fluorescent probe for detecting hydrogen polysulfides in living cells and zebra fish.Spectrochim. Acta A Mol. Biomol. Spectrosc., 2020, 224: 10.1016/j.saa.2019.1. A dual-ratiometric fluorescent probe for individual and continuous detection of H2S and HClO in living cells[J].Chem. Commun., 2020 (56) : 2849-285. A HBT-based bifunctional fluorescent probe for the ratiometric detection of fluoride and sulphite in real samples[J].Spectrochim. Acta A Mol. Biomol. Spectrosc., 2019, 219: 547-551. Simultaneous Discrimination of Cysteine, Homocysteine, Glutathione, and H2S in Living Cells through a Multisignal Combination Strategy[J].Anal. Chem., 2019, 91 (3) : 1904-1911. An ideal platform of light-emitting materials from phenothiazine: facile preparation, tunable red/NIR fluorescence, bent geometry-promoted AIE behaviour and selective lipid-droplet (LD) tracking ability[J].J. Mater. Chem. C, 2019, 7 (14) : 4185-4190. A ratiometric fluorescent probe for simultaneous detection of Cys/Hcy and GSH[J].Org. Biomol. Chem., 2019, 17 (44) : 9631-9635. Superoxide Radical Photogenerator with Amplification Effect: Surmounting the Achilles’ Heels of Photodynamic Oncotherapy[J].J. Am. Chem. Soc., 2019, 141 (6) : 2695-2702. An endoplasmic reticulum-targetable fluorescent probe for highly selective detection of hydrogen sulfide[J].Org. Biomol. Chem., 2019, 17 (6) : 1436-1441. A fluorescent probe for the dicriminatory detecion of Cys/Hcy, GSH and H2S in living cells and zebrafish[J].Sens. Actuator B: Chem., 2019, 296: 10.1016/j.snb.2019.0. A ratiometric flavone-based fluorescent probe for hypochlorous acid detection with large Stokes shift and long-wavelength emission[J].Dyes Pigm., 2019, 166: 390-394. An instantaneous fluorescent probe for detecting hydrogen sulfide in biological systems[J].New J. Chem., 2019, 43 (34) : 13594-13599. Simultaneous discrimination of Cys, Hcy, GSH and H2S in living cells through a multi-signal combination strategy.Anal. Chem., 2019, 91: 1904？1911.. Unexpected reaction patterns enable simultaneous differentiation of H2S, H2Sn and biothiols[J].Chem. Commun., 2019, 50 (56) : 8130-8133.