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个人简介

学习与工作经历 1995, 山东大学化学系,学士 2004, 瑞士巴塞尔大学(Basel University),Department of Chemistry,博士 2005-2009, 英国剑桥大学(Cambridge University),Department of Chemical Engineering and Biotechnology,博士后 2009-2011, 英国高科技上市公司 Nanoco Technologies Ltd,研究科学家 2011-至今, 青岛急需高层次人才,中国石油大学(华东),副教授 学生指导 指导本学院本科生科研项目“利用石墨烯量子点构建肿瘤靶向成像与治疗试剂”,在第十四届“挑战杯”全国大学生课外学术科技作品竞赛中荣获全国二等奖;指导硕士研究生孙星同学荣获罗伯托罗卡奖学金;课题组多名硕士研究生荣获国家奖学金;多位毕业生获得奖学金赴德国、香港、瑞士、澳大利亚进行科学研究及攻读博士学位;课题组依托《生物能源与材料创新型人才国际合作培养项目》可以支持组内学生出国读博或者联合培养。 承担科研项目 1. 海藻基碳纳米复合光催化剂用于土壤内多氯联苯类污染物降解处理的应用效果评价,青岛市民生科技计划,17-3-3-76-nsh,2017-2019; 2. 智能型短肽修饰荧光金纳米簇的构建及其标记细胞核仁与载运核酸片段的功能开发,山东省重点研发计划,GG201709280126, 2018-2020; 3. 石墨烯量子点对分子伴侣介导蛋白质折叠过程的影响及作用机理,山东省自然基金面上项目,ZR2017MB039,2017-2020; 4. 用于重大恶性肿瘤早期预警的等离子体纳米镀膜检测芯片关键技术,山东省重点研发计划项目,2015GSF118013,2015-2017; 5. 利用多肽修饰的无镉量子点作为荧光探针研究CXCR4在细胞膜上的运动,国家自然科学基金青年项目,21103230,2012-2014; 6. 无镉量子点在发光二极管技术中的应用,中央高校基本科研业务费专项基金,11CX05001A,2011-2013。 部分发明专利 1.曲剑波,王晓娟,陈艳丽,宦关生,朱虎,一种聚苯乙烯材料表面亲水改性的方法,201310315379.0 2.王晓娟,黄方,王雅楠,曲剑波,何化,王生杰,一种KCK多肽修饰的金纳米簇及其制备方法, 201610387321.0 3.王晓娟,曲剑波,王雅楠,黄方,何化,王生杰,一种多肽修饰的金纳米簇及其制备方法, 201610389189.7 4.王晓娟,陈奇,张政媛,黄方,王生杰,潘思远,葛保胜,何化,一种以海藻为碳源的荧光碳量子点的制备方法和用途, 201611128316.4 5.王晓娟,马锡琦,王雅楠,黄方,葛保胜,何化,一种基因载体系统及其构建方法, 201711350421.7 6.王晓娟,陈奇,黄方,葛保胜,刘真真,一种以碳量子点为荧光指示剂的酚类抗氧化剂测定方法, 201711350390.5 7.王生杰,王晓娟,荆倩,曹美文,夏永清,一种石墨烯分散液的制备方法,201711379802.8 8.王晓娟,马锡琦,黄方,葛保胜,孙怡鑫,一种以金纳米簇为荧光指示剂检测肝素钠中糖类杂质的方法, 201711430491.3

研究领域

化学工程,应用化学,材料化学与工程,生物化工

目前研究领域集中在量子点的应用,主要分为两个大的方向:一是生物标记及生物成像的应用,二是发光二极管(LED)的应用。同时对荧光纳米材料在各个领域的应用技术保持关注。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Wang, X.; Wang, Y.; He, H.; Ma, X.; Chen, Q.; Zhang, S.; Ge, B.; Wang, S.; Nau, W. M.; Huang, F., Deep-Red Fluorescent Gold Nanoclusters for Nucleoli Staining: Real-Time Monitoring of the Nucleolar Dynamics in Reverse Transformation of Malignant Cells. ACS Appl. Mater. Interfaces 2017,9 (21), 17799-17806. 2.Xia, Y.; Tang, Y.; Wu, H.; Zhang, J.; Li, Z.; Pan, F.; Wang, S.; Wang, X.; Xu, H.; Lu, J. R., Fabrication of Patterned Thermoresponsive Microgel Strips on Cell-Adherent Background and Their Application for Cell Sheet Recovery. ACS Appl. Mater. Interfaces 2017,9 (2), 1255-1262. 3. Qu, J.-B.; Xu, Y.-L.; Liu, Y.; Wang, Y.; Sui, Y.; Liu, J.-G.; Wang, X., Inherently Fluorescent Polystyrene Microspheres for Coating, Sensing and Cellular Imaging. Colloids Surf., B 2017,152, 475-481. 4. Lao, J.; He, H.; Wang, X.; Wang, Z.; Song, Y.; Yang, B.; Ullahkhan, N.; Ge, B.; Huang, F., Single-Molecule Imaging Demonstrates Ligand Regulation of the Oligomeric Status of CXCR4 in Living Cells. J. Phys. Chem. B 2017,121 (7), 1466-1474. 5. He, H.; Liu, X.; Li, S.; Wang, X.; Wang, Q.; Li, J.; Wang, J.; Ren, H.; Ge, B.; Wang, S.; Zhang, X.; Huang, F., High-Density Super-Resolution Localization Imaging with Blinking Carbon Dots. Anal. Chem. 2017,89 (21), 11831-11838. 6. Wang, X.; Wang, Y.; He, H.; Chen, X.; Sun, X.; Sun, Y.; Zhou, G.; Xu, H.; Huang, F., Steering Graphene Quantum Dots in Living Cells: Lighting up the Nucleolus. J. Mater. Chem. B 2016,4 (4), 779-784. 7. Wang, X.; He, H.; Wang, Y.; Wang, J.; Sun, X.; Xu, H.; Nau, W. M.; Zhang, X.; Huang, F., Active Tumor-Targeting Luminescent Gold Clusters with Efficient Urinary Excretion. Chem. Commun. 2016,52 (59), 9232-9235. 8. He, H.; Wang, Z.; Cheng, T.; Liu, X.; Wang, X.; Wang, J.; Ren, H.; Sun, Y.; Song, Y.; Yang, J.; Xia, Y.; Wang, S.; Zhang, X.; Huang, F., Visible and near-Infrared Dual-Emission Carbogenic Small Molecular Complex with High Rna Selectivity and Renal Clearance for Nucleolus and Tumor Imaging. ACS Appl. Mater. Interfaces 2016,8 (42), 28529-28537. 9. He, H.; Wang, X.; Cheng, T.; Xia, Y.; Lao, J.; Ge, B.; Ren, H.; Khan, N. U.; Huang, F., An Ultra-High Fluorescence Enhancement and High Throughput Assay for Revealing Expression and Internalization of Chemokine Receptor Cxcr4. Chem.--Eur. J. 2016,22 (17), 5863-5867. 10. Yue, T.; Wang, X.; Zhang, X.; Huang, F., Molecular Modeling of Interaction between Lipid Monolayer and Graphene Nanosheets: Implications for Pulmonary Nanotoxicity and Pulmonary Drug Delivery. RSC Adv. 2015,5 (38), 30092-30106. 11. Wang, X.; Sun, X.; He, H.; Yang, H.; Lao, J.; Song, Y.; Xia, Y.; Xu, H.; Zhang, X.; Huang, F., A Two-Component Active Targeting Theranostic Agent Based on Graphene Quantum Dots. J. Mater. Chem. B 2015,3, 3583-3590. 12. He, H.; Wang, X.; Feng, Z.; Cheng, T.; Sun, X.; Sun, Y.; Xia, Y.; Wang, S.; Wang, J.; Zhang, X., Rapid Microwave-Assisted Synthesis of Ultra-Bright Fluorescent Carbon Dots for Live Cell Staining, Cell-Specific Targeting and in Vivo Imaging. J. Mater. Chem. B 2015,3 (24), 4786-4789. 13. Wang, X.; Sun, X.; Lao, J.; He, H.; Cheng, T.; Wang, M.; Wang, S.; Huang, F., Multifunctional Graphene Quantum Dots for Simultaneous Targeted Cellular Imaging and Drug Delivery. Colloids Surf., B 2014,122, 638-644. 14. He, H.; Sun, X.; Wang, X.; Sun, Y.; Xu, H.; Lu, J. R., Cyclic Arginyl-Glycyl-Aspartic Acid (Rgd) Peptide-Induced Synthesis of Uniform and Stable One-Dimensional Cdte Nanostructures in Aqueous Solution. RSC Adv. 2014,4 (23), 11794-11797. 15. Wang, X.; Boschetti, C.; Ruedas-Rama, M. J.; Tunnacliffe, A.; Hall, E. A. H., Ratiometric Ph-Dot Ansors. Analyst 2010,135 (7), 1585-1591. 16. Wang, X.; Ruedas-Rama, M. J.; Hall, E. A. H., The Emerging Use of Quantum Dots in Analysis. Anal. Lett. 2007,40 (8), 1497-1520. 17. Ruedas-Rama, M. J.; Wang, X.; Hall, E. A. H., A Multi-Ion Particle Sensor. Chem. Commun. 2007, (15), 1544-1546. 18. Wang, X.; Nau, W. M., Kinetics of End-to-End Collision in Short Single-Stranded Nucleic Acids. J. Am. Chem. Soc. 2004,126 (3), 808-813. 19. Wang, X.; Bodunov, E. N.; Nau, W. M., Fluorescence Quenching Kinetics in Short Polymer Chains: Dependence on Chain Length. Optics and Spectroscopy 2003,95 (4), 560-570. 20. Zhang, X. Y.; Gramlich, G.; Wang, X.; Nau, W. M., A Joint Structural, Kinetic, and Thermodynamic Investigation of Substituent Effects on Host-Guest Complexation of Bicyclic Azoalkanes by Beta-Cyclodextrin. J. Am. Chem. Soc. 2002,124 (2), 254-263. 21. Nau, W. M.; Wang, X., Biomolecular and Supramolecular Kinetics in the Submicrosecond Time Range: The Fluorazophore Approach. ChemPhysChem 2002,3 (5), 393-398. 22. Wang, X.; Nau, W. M., Kinetics of One- and Two-Directional Charge Hopping in One-Dimensional Systems: Application to DNA. ChemPhysChem 2001,2 (12), 761-766.

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