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Select item 25689339 Erratum: Covalent docking of large libraries for the discovery of chemical probes. London N, Miller RM, Krishnan S, Uchida K, Irwin JJ, Eidam O, Gibold L, Cimermančič P, Bonnet R, Shoichet BK, Taunton J. Nat Chem Biol. 2015 Feb 17;11(3):235. doi: 10.1038/nchembio0315-235b. No abstract available. PMID: 25689339 [PubMed - in process] Select item 25689261 Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function. Heo KS, Le NT, Cushman HJ, Giancursio CJ, Chang E, Woo CH, Sullivan MA, Taunton J, Yeh ET, Fujiwara K, Abe J. J Clin Invest. 2015 Mar 2;125(3):1299-310. doi: 10.1172/JCI76453. Epub 2015 Feb 17. PMID: 25689261 [PubMed - in process] Select item 25619841 Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum. Ruiz-Saenz A, Sandhu M, Carrasco Y, Maglathlin RL, Taunton J, Moasser MM. Oncogene. 2015 Jan 26. doi: 10.1038/onc.2014.455. [Epub ahead of print] PMID: 25619841 [PubMed - as supplied by publisher] Select item 25399643 Targeting protein kinases with selective and semipromiscuous covalent inhibitors. Miller RM, Taunton J. Methods Enzymol. 2014;548:93-116. doi: 10.1016/B978-0-12-397918-6.00004-5. PMID: 25399643 [PubMed - in process] Free PMC Article Select item 25344815 Covalent docking of large libraries for the discovery of chemical probes. London N, Miller RM, Krishnan S, Uchida K, Irwin JJ, Eidam O, Gibold L, Cimermančič P, Bonnet R, Shoichet BK, Taunton J. Nat Chem Biol. 2014 Dec;10(12):1066-72. doi: 10.1038/nchembio.1666. Epub 2014 Oct 26. PMID: 25344815 [PubMed - indexed for MEDLINE] Select item 25153195 Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis. Krishnan S, Miller RM, Tian B, Mullins RD, Jacobson MP, Taunton J. J Am Chem Soc. 2014 Sep 10;136(36):12624-30. doi: 10.1021/ja505194w. Epub 2014 Sep 2. PMID: 25153195 [PubMed - in process] Free PMC Article Select item 24497544 An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate. Mackinnon AL, Paavilainen VO, Sharma A, Hegde RS, Taunton J. Elife. 2014;3:e01483. doi: 10.7554/eLife.01483. Epub 2014 Feb 4. PMID: 24497544 [PubMed - in process] Free PMC Article Select item 24357642 Examining injury risk and pain perception in runners using minimalist footwear. Ryan M, Elashi M, Newsham-West R, Taunton J. Br J Sports Med. 2014 Aug;48(16):1257-62. doi: 10.1136/bjsports-2012-092061. Epub 2013 Dec 19. PMID: 24357642 [PubMed - in process] Select item 24225074 Creating a gold medal Olympic and Paralympics health care team: a satisfaction survey of the mobile medical unit/polyclinic team training for the Vancouver 2010 winter games. Brown DR, Heidary B, Bell N, Appleton L, Simons RK, Evans DC, Hameed SM, Taunton J, Khwaja K, O'Connor M, Garraway N, Hennecke P, Kuipers D, Taulu T, Quinn L. BMC Res Notes. 2013 Nov 13;6:462. doi: 10.1186/1756-0500-6-462. PMID: 24225074 [PubMed - indexed for MEDLINE] Free PMC Article Select item 24172656 Comparison of a physiotherapy program versus dexamethasone injections for plantar fasciopathy in prolonged standing workers: a randomized clinical trial. Ryan M, Hartwell J, Fraser S, Newsham-West R, Taunton J. Clin J Sport Med. 2014 May;24(3):211-7. doi: 10.1097/JSM.0000000000000021. PMID: 24172656 [PubMed - indexed for MEDLINE] Select item 24085294 The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis. Li D, Jin L, Alesi GN, Kim YM, Fan J, Seo JH, Wang D, Tucker M, Gu TL, Lee BH, Taunton J, Magliocca KR, Chen ZG, Shin DM, Khuri FR, Kang S. J Biol Chem. 2013 Nov 8;288(45):32528-38. doi: 10.1074/jbc.M113.500561. Epub 2013 Oct 1. PMID: 24085294 [PubMed - indexed for MEDLINE] Free PMC Article Select item 23853713 Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei [corrected]. Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J. Elife. 2013 Jul 9;2:e00712. doi: 10.7554/eLife.00712. Erratum in: Elife. 2013;e01214. PMID: 23853713 [PubMed - in process] Free PMC Article Select item 23608533 p90 RSK2 mediates antianoikis signals by both transcription-dependent and -independent mechanisms. Jin L, Li D, Lee JS, Elf S, Alesi GN, Fan J, Kang HB, Wang D, Fu H, Taunton J, Boggon TJ, Tucker M, Gu TL, Chen ZG, Shin DM, Khuri FR, Kang S. Mol Cell Biol. 2013 Jul;33(13):2574-85. doi: 10.1128/MCB.01677-12. Epub 2013 Apr 22. PMID: 23608533 [PubMed - indexed for MEDLINE] Free PMC Article Select item 23540679 Electrophilic fragment-based design of reversible covalent kinase inhibitors. Miller RM, Paavilainen VO, Krishnan S, Serafimova IM, Taunton J. J Am Chem Soc. 2013 Apr 10;135(14):5298-301. doi: 10.1021/ja401221b. Epub 2013 Mar 29. PMID: 23540679 [PubMed - indexed for MEDLINE] Free PMC Article Select item 23438743 Proteostasis modulators with discriminating taste. Paavilainen VO, Taunton J. Chem Biol. 2013 Feb 21;20(2):144-5. doi: 10.1016/j.chembiol.2013.02.002. PMID: 23438743 [PubMed] Free PMC Article Select item 23400640 Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target. Choy JW, Bryant C, Calvet CM, Doyle PS, Gunatilleke SS, Leung SS, Ang KK, Chen S, Gut J, Oses-Prieto JA, Johnston JB, Arkin MR, Burlingame AL, Taunton J, Jacobson MP, McKerrow JM, Podust LM, Renslo AR. Beilstein J Org Chem. 2013;9:15-25. doi: 10.3762/bjoc.9.3. Epub 2013 Jan 4. PMID: 23400640 [PubMed] Free PMC Article Select item 23243209 A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. PMID: 23243209 [PubMed - indexed for MEDLINE] Free PMC Article Select item 23199426 A prospective study of physician-observed concussion during a varsity university hockey season: white matter integrity in ice hockey players. Part 3 of 4. Koerte IK, Kaufmann D, Hartl E, Bouix S, Pasternak O, Kubicki M, Rauscher A, Li DK, Dadachanji SB, Taunton JA, Forwell LA, Johnson AM, Echlin PS, Shenton ME. Neurosurg Focus. 2012 Dec;33(6):E3: 1-7. doi: 10.3171/2012.10.FOCUS12303. PMID: 23199426 [PubMed - indexed for MEDLINE] Select item 23199425 A prospective study of physician-observed concussion during a varsity university ice hockey season: incidence and neuropsychological changes. Part 2 of 4. Echlin PS, Skopelja EN, Worsley R, Dadachanji SB, Lloyd-Smith DR, Taunton JA, Forwell LA, Johnson AM. Neurosurg Focus. 2012 Dec;33(6):E2: 1-11. doi: 10.3171/2012.10.FOCUS12286. PMID: 23199425 [PubMed - indexed for MEDLINE] Select item 23190395 Selective targeting of distinct active site nucleophiles by irreversible SRC-family kinase inhibitors. Gushwa NN, Kang S, Chen J, Taunton J. J Am Chem Soc. 2012 Dec 19;134(50):20214-7. doi: 10.1021/ja310659j. Epub 2012 Dec 4. PMID: 23190395 [PubMed - indexed for MEDLINE] Free PMC Article