个人简介
许佑君，男，安徽六安市人，东京大学博士，沈阳药科大学教授、药物化学系主任。药物化学博士生导师、有机化学和制药工程兼职硕士生导师。主要从事心脑血管、代谢性疾病治疗药的研发，手性小分子的不对称合成与活性评价，药物合成新方法的研究等。近年来，陆续主持了多项国家、省市自然科学基金项目等，负责完成了国家攻关项目、重大专项的合成研究工作；先后主持了新药合成与产业化项目19项，已获新药证书9个、中国专利7项；先后数次获省、市级科技进步奖。
近期论文
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1.JiaanLiu,XiaopengGuo,ShuangLiang,FeiAn,HongyanShen,YoujunXu.RegioselectiveSynthesisof5'-AminoAcidEstersofSomeNucleosidesviaOrthogonalProtectingProtocol[J].Tetrahedron,2015,71(9),1409-12.(IF2.645)
2.WeiLi,ZhoulongFan,KaijunGeng,YoujunXu,AoZhang.Late-stagediversificationofbiologicallyactivepyridazinonesviaadirectC–Hfunctionalizationstrategy[J].Org.Biomol.Chem.,2015,13(2),539-48.(IF3.559)
3.XueJiang,MeiningWang,ShanshanSong,YoujunXu,ZehongMiao,AoZhang.ChemInformAbstract:Design,Synthesis,andAnticancerActivitiesofNewCompoundsBearingtheQuinone-Pyran-LactoneTricyclicPharmacophore[J].ChemInform,2015,46(32):27502-08.(IF3.949)
4.YanGuo,HuaZhang,HaoYan,HailongXin,HongyanShen,YoujunXu.Concisesynthesisofdopexaminedihydrochlorideviabenzylprotectingprotocol[J].Chin.Chem.Lett.,2015,26(3),357-60.(IF1.947)
5.YouxiZhang,JinSun,YikunGao,LingJin,YoujunXu,HeLian,YongbingSun,YinghuaSun,JianyuLiu,RuiFan,TianhongZhang,ZhongguiHe.Acarrier-mediatedprodrugapproachtoimprovetheoralabsorptionofantileukemicdrugdecitabine.Mol.Pharm.,2013,10(8),3195-202.(IF4.12)
6.DongyuWang,ShanshanSong,YeTian,YoujunXu,ZehongMiao,AoZhang.TotalsynthesisofthemarinecyclicdepsipeptideviequeamideA.J.Nat.Prod.,2013,76(5):974-78.(IF3.947)
7.JizhiNi,HepingXiao,LipengWeng,XiaofengWei,YoujunXu.Blockinggroup-directeddiastereoselectivetotalsynthesisof(±)-α-noscapine.Tetrahedron,2011,67(29),5162-67.(IF3.219)
8.ZhongtianYan,JinSun,YannanChang,YanhuaLiu,QiangFu,YoujunXu,YongbingSun,XiaohuiPu,YouxiZhang,YongkuiJing,ShiliangYin,MengZhu,YongjunWang,ZhongguiHe.Bifunctionalpeptidomimeticprodrugsofdidanosineforimprovedintestinalpermeabilityandenhancedacidicstability:synthesis,transepithelialtransport,chemicalstabilityandpharmacokinetics.Mol.Pharm.,2011,8(1),319-29.(IF4.531)
9.ZhongtianYan,JinSun,JinlingWang,YoujunXu,YannanChang,PingMeng,MengZhu,QiangFu,YongbingSun,ZhongguiHe.Simultaneousdeterminationofdidanosineanditsaminoacidprodrug,valdidanosinebyhydrophilicinteractionchromatographycoupledwithelectrosprayionizationtandemmassspectrometry:Applicationtoapharmacokineticstudyinrats.J.Chromatogr.B,2010,878,466-70.(IF2.777)
10.GangLu,RobertFranzen,QianZhang,YoujunXu,Palladiumcharcoal-catalyzed,ligandlesssuzukireactionbyusingtetraarylboratesinwater.TetrahedronLett.2005,46(24),4255-59.(IF2.477)
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