个人简介
胡春,男,博士,教授。1985年毕业于江苏师范大学,获化学学士学位,1988年毕业于东北师范大学,获有机化学硕士学位,1999年毕业于沈阳药科大学,获药物化学博士学位,2014年在香港中文大学作为高级访问学者进修一年。1988年起在沈阳药科大学工作至今,1995被评为沈阳药科大学副教授,2000年晋升为教授,2002年被评为博士生导师。作为课题负责人完成了国家自然科学基金项目3项,国家新药研究基金2项,国家重大科技专项1项。目前已在ARKIVOC,MedicinalChemistry,Heterocycles,Bioorganic&MedicinalChemistryLetters,ChemicalResearchinChineseUniversities,LettersinDrugDesign&Discovery,Chemico-BiologicalInteractions,ChineseChemicalLetters,LatinAmericanJournalofPharmacy,Molecules等期刊发表论文100余篇,其中SCI收载30余篇。
研究领域
研究方向一:杂环化合物的合成及生物活性研究
研究方向二:医药中间体的研究
研究方向三:金属有机化合物的合成及生物活性研究
新药设计与合成、医药中间体的研究、杂环化合物的合成及生物活性研究、金属有机化合物的合成及生物活性研究等
近期论文
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1.ZHANGLan,DENGXinshan,WUJiaofeng,MENGGuangpeng,LIUCongchong,CHENGuzhou,ZHAOQingchun,HUChun.Design,SynthesisandBiologicalActivitiesofN-(Furan-2-ylmethyl)-1H-indole-3-carboxamideDerivativesasEpidemalGrowthFactorReceptorInhibitorsandAnticancerAgents.ChemicalResearchinChineseUniversities,2017,33(3):365-372.
2.LanZhang,Xin-ShanDeng,ChaoZhang,Guang-PengMeng,Jiao-FengWu,Xue-SongLi,Qing-ChunZhao,ChunHu.Design,synthesisandcytotoxicevaluationofanovelseriesofbenzo[d]thiazole-2-carboxamidederivativesaspotentialEGFRinhibitors.MedicinalChemistryResearch,2017,26(9):2180-2189.
3.WenjingYe,XiaoXiao,LanWang,ShichengHou,ChunHu.Synthesisofmono-andbinuclearCu(ii)complexesbearingunsymmetricalbipyridine–pyrazole–amineligandandtheirapplicationsinazide–alkynecycloaddition.Organometallics,2017,36(11):2116–2125.
4.BingSUN,JinZHANG,Xiu’eYIN,YueXU,FurongZHANG,YushuHUANG,JinhuiWANG,GuoqingWANG&ChunHU.Synthesis,CharacterizationandBiologicalActivityofthieno[2,3-d]pyrimidineDerivativesastheEpidermalGrowthFactorReceptorInhibitors.LatinAmericanJournalofPharmacy,2016,35(3):570-577.
5.LIHan-Yue,HANYu,JINZhe,WANGShi-Hui,LIXin-Zeng,LIUSi-Yu,HUChun.TheCrystalStructureof3-(4-methoxyphenyl)-2-(4-methylbenzoyl)-6,7-dihydro-5H-furo[3,2-g]chromene.ChineseJournalofStructuralChemistry,2016,35(4):545-549.
6.GangLi,LiangZhao,PengYang,ZhaozhengYang,ZhangminTian,YanChen,HongyanShen,andChunHu.Engineering1,3-AlternateCalixcarbazoleforRecognitionandSensingofBisphenolFinWater.AnalChem.2016,88(21):10751-10756.
7.Xiao-pingLiu,Hui-lanXu,RuiSun,XueLi,Bao-huaHu,ChunHu.SynthesisandCharacterizationofTwoImpuritiesinEsomeprazole,anAntiulcerativeDrug.LatinAmericanJournalofPharmacy,2015,34(6):1265–1268.
8.BingSun,Xiu’eYin,JinZhang,JianHuang,YueXu,FurongZhang,JinhuiWang,GuoqingqingWang,ChunHu.Synthesis,CharacterizationandBiologicalActivityofTetrahydrobenzo[4,5]thieno[2,3-d]pyrimidineDerivativesasEpidermalGrowthFactorReceptorInhibitors.ChemicalResearchinChineseUniversities,2015,31(6):936-941.
9.JianshuHu,WeiZhu,HuMeng,YingLiu,XinWangandChunHu.Identificationof1,4-Dihydrothieno[3′,2′:5,6]thiopyrano[4,3-c]pyrazoleDerivativesasHuman5-Lipo-oxygenaseInhibitors.ChemicalBiologyandDrugDesign,2014,84(6):642–647.
10.XinWang,RuiSun,YushuHuang,YisiYan,MiaomiaoGao,DanniWang,DiwaKoirala,DaweiLi,ChunHu.DevelopmentofThieno[3',2':5,6]thiopyrano[4,3-c]pyrazole-3-carboxamideDerivativesastheEstrogenReceptorLigands:Synthesis,CharacterizationandBiologicalActivity.MedicinalChemistry,2014,10(8):836-942.
学术兼职
1.教育部医药公共基础课程教学指导委员会委员;
2.辽宁省化学专业教学指导委员会委员;
3.沈阳市科技咨询专家;
4.《中国药物化学杂志》编委;
5.《沈阳药科大学学报》编委;
6.《精细化工中间体》杂志编委
7.2000年入选辽宁省“百千万人才工程”百人层次培养计划