杜为红 - 中国人民大学

个人简介

教育背景： 1986.9-1990.7, 山西大学化学系, 本科 1990.9-1993.7, 山西大学分子科学研究所, 硕士 1997.9-2000.7, 北京大学化学与分子工程学院, 博士工作经历： 1993.7-1997.8, 山西大学化学系，教师 2000.9-2001.3, 香港大学化学系，博士后 2001.4-2003.4, 美国加州大学戴维斯分校化学系，博士后 2003.8-2005.5, 北京师范大学化学系, 教师 2005.6-, 中国人民大学化学系，教师

研究领域

生物大分子与配体相互作用的光谱学、波谱学研究生物毒素的结构与功能关系生物大分子与小分子相互作用的热动力学

近期论文

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Jia Xu, Gowei Yin, Weihong Du*. Distal mutation modulates the heme sliding in mouse neuroglobin investigated by molecular dynamics simulation. Proteins. Struc. Func. Bioinfo. 2011, 79, 191-202. Yanli Wang, Jia Xu, Lu Wang, Bingbing Zhang, Weihong Du*. Interaction of the human prion protein PrP106-126 with metal complexes: potential therapeutic agents against prion disease. Chemistry, Eur. J. 2010, 16, 13339-42. Yanli Wang, Tong Zhang*, Jia Xu, Weihong Du*. Comparison of the binding affinity of chlorogenic acid with two serum albumins. Int. J. Biol. Macromol. 2010, in press. Jia Xu, Yanli Wang, Binbin Zhang, Baohuai Wang, Weihong Du*. Stereochemistry of 4-hydroxyproline affects the conformation of conopeptides. Chem. Commun. 2010, 46, 5467-5469. Jia Xu, Guowei Yin, Feijuan Huang, Baohuai Wang, Weihong Du*. Molecular dynamics simulation of a carboxy murine neuroglobin mutated on the proximal side: heme displacement and concomitant rearrangement in loop regions J. Mol. Model. 2010, 16, 759-770. Bin Gao, Jia Xu, Maria del Carmen Rodrigues, Humberto Lanz-Mendoza, Rosaura Hernondez -Rivas, Weihong Du*, Shunyi Zhu*. Characterization of two linear cationic antimalarial peptides in the scorpion mesobuthus eupeus. Biochimie 2010, 92, 350-359. Jia Xu, Lianzhi Li, Guowei Yin, Haili Li, Weihong Du*. Ligand orientation of human neuroglobin obtained from solution NMR and molecular dynamics simulation as compared with X-ray crystallography. J. Inorg. Biochem. 2009, 103, 1693-1701. Feijuan Huang, Weihong Du*, Solution Structure of Hyp10Pro variant of conomarphin, a cysteine-free and D-amino-acid containing conopeptide. Toxicon, 2009, 54, 153-160. Yuhong Han, Feijuan Huang, Hui Jiang, Li Liu, Qi Wang, Yanfang Wang, Xiaoxia Shao, Chengwu Chi, Weihong Du* and Chunguang Wang* , Purification and structural characterization of a D-amino acid containing conopeptide, conomarphin, from conus marmoreus. FEBS J. 2008, 275, 1976-1987. Guowei Yin, Yanjie Li, Juan Li, Jing Li, Weihong Du*, Qun Wei*, Weihai Fang. Solution H-1 NMR study of the active site structure for the double mutant H64Q/V68F cyanide complex from mouse neuroglobin. Biophys. Chem. 2008, 136, 115-123. Weihong Du, Yuhong Han, Feijuan Huang, Juan Li, Chengwu Chi, Weihai Fang*. Solution structure of an M-1 Conotoxin mr3e with a novel disulfide linkage. FEBS J. 2007, 274, 2596-2602. Yiming Li, Guowei Yin, Wei Wei, Hengbin Wang, Shanhao Jiang, Duyuan Zhu*, Weihong Du*, Interactions of Lycopodium alkaloids with acetylcholinesterase investigated by 1H NMR relaxation rate, Biophys. Chem. 2007, 129, 212-217. Weihong Du, Ling Wang, Baohuai Wang, Zhifen Li, Weihai Fang*. Actinoimycin D binds to single stranded DNA oligomers which contains double GTC triplets. Thermochimica Acta 2007, 452, 31-35. Weihong Du, Ray Syvitski, Sylvia Dewilde, Luc Moens, and Gerd N. La Mar*. Solution 1H NMR Characterization of Equilibrium Heme Orientational Disorder with Functional Consequence in Mouse Neuroglobin. J. Am. Chem. Soc. 2003, 125, 8080-8081. Weihong Du, Zhicheng Xia, Sylvia Dewilde, Luc Moens, Gerd N. La Mar*. 1H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid globin from trametode Paraphistomum epiclitum. Eur. J. Biochem. 2003, 270, 2707-2720.