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个人简介

学习经历 曲阜师范大学(1989);中国科学院成都有机化学研究所硕士(1995); 中国科学院化学研究所博士(1998) 工作经历 1998.10 - 2000.11 The University of Liverpool 博士后 2001.1 - 2001.11 Loughborough University 博士后 2001.12 – 2005.7 香港理工大学 博士后 2005.8至今 中国人民大学化学系 副教授 、教授

研究领域

(1) 过渡金属催化的不对称有机合成方法学研究 (2) 过渡金属催化的杂原子化合物的有机合成方法学研究 (3) 以DNA生物大分子为模版的化学研究

近期论文

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Ji Yang, Changjun Chen, Haoqiang Zhao, Bohan Li, Zhenni He, Lijin Xu,* Qian Shi,* Rhodium(III-Catalyzed C8-Selective C-H Alkenylation and Alkylation of 1, 2, 3, 4-Tetrahydroquinolines with Styrenes and Allylic Alcohols. Adv. Synth. Catal. 2023, 365, 1027–1035. Zhen Yao, Gang Li, Ying Zhou, Lijin Xu,* Dong Xue,* Visible-Light Photoredox-Catalyzed Decarboxylative Double Difluoromethylation of β,γ-Unsaturated Carboxylic Acids for the Synthesis of Difluoromethylated Allylic Compounds. Adv. Synth. Catal. 2023, 365, 224–229. Haoqiang Zhao,* Qi Zeng, Ji Yang, Bing Xu, Haimin Lei, Lijin Xu,*Patrick J. Walsh,* Rhodium(I)-Catalyzed Directed Trideuteromethylation of (Hetero)arene C–H Bonds with CD3CO2D. Org. Biomol. Chem. 2022, 20, 7645–7649. Haoqiang Zhao, Zhenli Luo, Ji Yang, Bohan Li, Jiahong Han, Lijin Xu,* Wenzhen Lai,* Patrick J. Walsh*, Ligand-Promoted RhI-Catalyzed C2-Selective C-H Alkenylation and Polyenylation of Imidazoles with Alkenyl Carboxylic Acids. Chem. Eur. J. 2022, 28, e202200441 (1 of 9). Zhen Yao, Ji Yang, Zhenli Luo, Heyu Wang, Xin Zhang, Jianhan Ye, Lijin Xu,*Qian Shi *, Photo-driven Metal-free Multicomponent Reaction between Aldehydes, Anilines and 4-Substituted-DHPs for the Synthesis of Secondary Amines. Green Chem. 2022, 24, 7968–7973. Yixiao Pan, Zhenli Luo, Ji Yang, Jiahong Han, Jianbo Yang, Zhen Yao, Lijin Xu,* Peng Wang,* Qian Shi,* Cobalt-Catalyzed Selective Transformation of Levulinic Acid and Amines into Pyrrolidines and Pyrrolidinones using Hydrogen. Adv. Synth. Catal. 2022, 364, 2830–2836. Zhenli Luo, Shanhong Wan, Yixiao Pan, Zhen Yao, Xin Zhang, Bohan Li, Jiajie Li, Lijin Xu,* Qing-Hua Fan*, Metal-Free Reductive Amination of Ketones with Amines Using Formic Acid as the Reductant under BF3·Et2O Catalysis. Asian J. Org. Chem. 2022, 11, e202100707 (1 of 7). Zhen Yao, Ji Yang, Zhenli Luo, Jianhan Ye, Jiahong Han, Xin Zhang, Lijin Xu,* Peng Wang,* Qian Shi,* Visible-Light Photoredox-Catalyzed Tandem One-Pot Construction of C4-Difluoroalkylated Phthalazin-1(2H)-Ones, Adv. Synth. Catal. 2022, 364, 2852–2858. Jiajie Li, Xin Xu, Zhenli Luo, Zhen Yao, Ji Yang, Xin Zhang, Lijin Xu,*Peng Wang,* Qian Shi,* Rhodium(III)-Catalyzed Regioselective C–H Annulation and Alkenylation of 2-Pyridones with Terminal Alkynes. Adv. Synth. Catal. 2022, 364, 1264–1270. Zhen Yao, Zhenli Luo, Yixiao Pan, Xin Zhang, Bohan Li, Lijin Xu,* Peng Wang,* Qian Shi,* Metal-Free Tandem One-Pot Construction of 3,3-Disubsituted 3,4-Dihydroquinoxalin-2(1H)-Ones under Visible-Light Photoredox Catalysis. Adv. Synth. Catal. 2022, 364, 658–664. Xin Zhang, Yu-Dong Yang, Zhi-Hao Lu, Li-Jin Xu*, Jonathan L. Sesslerc, Han-Yuan Gong, Synergistic Regulation of Nonbinary Molecular Switches by Protonation and Light. PNAS 2021, 118, e2112973118. Haoqiang Zhao, Jianbin Xu, Xin Xu, Yixiao Pan, Zexin Yu, Lijin Xu, *Qinghua Fan,* Patrick J. Walsh,* Rh(I)-Catalyzed Direct C6–H Arylation of 2-Pyridones with Aryl Carboxylic Acids. Adv. Synth. Catal. 2021, 363, 3995– 4001. Chao Gao, Jiwang Fang, Lijin Xu,* Hanyuan Gong*, A Mild Silica Gel Promoted Synthesis and Initial Functional Study of Tetrapyridyl Tetrahydropyrrolopyrrolones. Org. Lett. 2022, 24, 5397–5401. Xu, Xin; Luo, Chenguang; Zhao, Haoqiang; Pan, Yixiao; Zhang, Xin; Li, Jiajie; Xu, Lijin;* Lei, Ming; Walsh, J. Patrick, Rhodium(III)-Catalyzed C−H Bond Functionalization of 2-Pyridones with Alkynes: Switchable Alkenylation, Alkenylation/Directing Group Migration and Rollover Annulation. Chemistry-A European Journal 2021, 27, 8811–8821. Xin Xu, Lin Zhang, Haoqiang Zhao, Yixiao Pan, Jiajie Li, Zhenli Luo, Jiahong Han, Lijin Xu*, Ming Lei*, Cobalt(III)-Catalyzed Regioselective C6 Olefination of 2‑Pyridones Using Alkynes: Olefination/Directing Group Migration and Olefination. Org. Lett. 2021, 23, 4624−4629. Wan, Shanhong; Luo, Zhenli; Xu, Xin; Yu, Haiyang; Li, Jiajie; Pan, Yixiao; Zhang, Xin; Xu, Lijin;* Cao, Rui, Manganese(I)-Catalyzed Site-Selective C6-Alkenylation of 2-Pyridones Using Alkynes via C-H Activation. Advanced Synthesis & Catalysis 2021, 363, 2586– 2593. Wang, Xinyu; He, Zhongyu; Xu, Xin; Zhao, Haoqiang; Pan, Yixiao; Li, Huanrong; Xu, Lijin,* Rh(III)-catalyzed C6-selective Acylmethylation and Carboxymethylation of 2-Pyridones with Diazo Compounds. ChemCatChem 2021, 13, 1730-1737. Yu, Haiyang; Zhao, Haoqiang, Xu, Xin; Zhang, Xin; Yu, Zexin; Li. Lingchao; Wang, Peng; Shi, Qian; Xu, Lijin,* Rhodium(I)-Catalyzed C2-Selective Decarbonylative C-H Alkylation of Indoles with Alkyl Carboxylic Acids and Anhydrides. Asian Journal of Organic Chemistry 2021, 10, 879-885. Fang, Ji-Wang; Liao, Fang-jie; Qian, Yang; Dong, Chao-Chen; Xu, Li-Jin;* Gong, Han-Yuan, One-Pot Synthesis of 3-Substituted 4H‑Quinolizin-4-ones via Alkyne Substrate Control Strategy. J. Org. Chem. 2021, 86, 3648-3655. Haoqiang Zhao, Bowen Hu, Lijin Xu,* Patrick J. Walsh,* Palladium-catalyzed Benzylic C(sp3)–H Carbonylative Arylation of Azaarylmethyl Amines with Aryl Bromides. Chem. Sci. 2021, 12, 10862–10870. Yao, Zhen; Liu, Xiong-Wei; Li, Zheng; Xu, Sheng-Wen; Xu, Lijin;* Liu, Xiong-Li, Dienolate-Mediated, Regioselective C2-Polarity Reversal of Chromone-Based Reactants and Their Application in Nucleophilic Strategies. Advanced Synthesis & Catalysis 2020, 362, 5352-5357. Zhao, Haoqiang; Xu, Xin; Yu, Haiyang; Li, Bohan; Xu, Xingyu; Li, Huanrong; Xu, Lijin;* Fan, Qinghua; Walsh, Patrick J., Rh(I)-Catalyzed C6-Selective Decarbonylative Alkylation of 2-Pyridones with Alkyl Carboxylic Acids and Anhydrides. Organic Letters 2020, 22, 4228-4234. Li, Yanwen; Zhang, Yangang; Yang, Zhuo; Xue, Xiao; He, Zhongyu; Wang, Huiqun; Wang, Chen; Qu, Jian; Feng, Ya; Zhang, Weidong; Xu, Lijin,* Waterborne Coatings with Sub-ambient Cooling under Direct Sunlight-part I: Optical Properties and Cooling Effect Measurements. Solar Energy Materials & Solar Cells 2020, 217, 110672. Sun, Yawei; Yang, Bo; Hua, Yi; Dong, Yuanchen; Ye, Jianhan; Wang, Jiqian; Xu, Lijin; Liu, Dongsheng, Construction and Characterization of a Mirror-Image l-DNA i-Motif. ChemBioChem 2020, 21, 94-97. He, Zhongyu; Li, Yanwen; Zhang, Yangang; Xue, Xiao; Yang, Zhuo; Wang, Huiqun; Wang, Chen; Qin, Jie; Feng, Ya; Zhang, Weidong; Xu, Lijin,* Waterborne Coatings with Sub-ambient Cooling under Direct Sunlight-Part II: Cooling Effect under Real Working Conditions and Key Physical Properties. Solar Energy Materials & Solar Cells 2020, 215, 110665. Pan, Yixiao; Li, Yanwen; Han, Jiahong; Zhao, Haoqiang; Feng, Yu; Ding, Xiangyuan; Xu, Lijin;* Fan, Qinghua; Shi, Qian, Synthesis of 1,2,3,4-Tetrahydroquinoxalines Through a One-pot Tandem Reaction Involving Cyclization and Hydrogenation of Imine and Amide Moieties. Chemical Journal of Chinese Universities-Chinese 2020, 41, 2239-2255. Qian,Yang; Shang, Jia; Lyu, Zhen-Hua; Huang, Xin; Guan, Ai-jiao; Xu, Li-Jin;* Gong, Han-Yuan, Synthesis of π-Extended Carbazoles via One-Pot C-C Coupling and Chlorination Promoted by FeCl3. Chinese Journal of Chemistry 2020, 38, 1538-1544. Xue, Xiao; Qiu, Meng; Li, Yanwen; Zhang, Q. M.; Li, Siqi; Yang, Zhuo; Feng, Chi; Zhang, Weidong; Dai, Jian-Guo; Lei, Dangyuan; Jin, Wei; Xu, Lijin; Zhang, Tao; Qin, Jie; Wang, Huiqun; Fan, Shanhui, Creating an Eco-Friendly Building Coating with Smart Subambient Radiative Cooling. Advanced Materials 2020, 32, 1906751. Pan, Yixiao; Luo, Zhenli; Han, Jiahong; Xu, Xin; Chen, Changjun; Zhao, Haoqiang; Xu, Lijin;* Fan, Qinghua; Xiao, Jianliang, B(C6F5)3-Catalyzed Deoxygenative Reduction of Amides to Amines with Ammonia Borane. Advanced Synthesis & Catalysis 2019, 361, 2301-2308. Pan, Yixiao; Luo, Zhenli; Xu, Xin; Zhao, Haoqiang; Han, Jiahong; Xu, Lijin;* Fan, Qinghua; Xiao, Jianliang, Ru-Catalyzed Deoxygenative Transfer Hydrogenation of Amides to Amines with Formic acid/Triethylamine. Advanced Synthesis & Catalysis 2019, 361, 3800-3806. Liu, Yaqian; Shao, Zhihui; Wang, Yujie; Xu, Lijin;* Yu, Zhiyong; Liu, Qiang, Manganese-Catalyzed Selective Upgrading of Ethanol with Methanol into Isobutanol. ChemSusChem 2019, 12, 3069-3072. Zhang, Bo; Wang, Yao; Thi, Shiki; Toong, Vincent; Luo, Ping; Fan, Shilong; Xu, Lijin;* Yang, Zhongqiang; Heng, Jerry Y. Y., Enhancement of Lysozyme Crystallization Using DNA as a Polymeric Additive. Crystals 2019, 9, 186. Zhao, Haoqiang; Xu, Xin; Luo, Zhenli; Cao, Lei; Li, Bohan; Li, Huanrong; Xu, Lijin;* Fan, Qinghua; Walsh, Patrick J., Rhodium(i)-catalyzed C6-selective C-H Alkenylation and Polyenylation of 2-Pyridones with Alkenyl and Conjugated Polyenyl Carboxylic Acids. Chemical Science 2019, 10, 10089-10096. Zhou, Yongyun; Khan, Ruhima; Fan, Baomin; Xu, Lijin,* Ruthenium-Catalyzed Selective Reduction of Carboxylic Esters and Carboxamides. Synthesis-Stuttgart 2019, 51, 2491-2505. Chen, Changjun; Pan, Yixiao; Zhao, Haoqiang; Xu, Xin; Xu, Jianbin; Zhang, Zongyao; Xi, Siqi; Xu, Lijin;* Li, Huanrong, A versatile rhodium(III) catalyst for direct acyloxylation of aryl and alkenyl C-H bonds with carboxylic acids. Organic Chemistry Frontiers 2018, 5, 415-422. Xu, Jianbin; Chen, Changjun; Zhao, Haoqiang; Xu, Conghui; Pan, Yixiao; Xu, Xin; Li, Huanrong; Xu, Lijin;* Fan, Baomin, Rhodium(i)-catalysed decarbonylative direct C-H vinylation and dienylation of arenes. Organic Chemistry Frontiers 2018, 5, 734-740. Chen,Yun; Wang, Zi-Xuan; Li, Qian; Xu, Li-Jin;* Li, Bi-Jie, Iridium-catalysed Conjugated Alkynylation of α,β-Unsaturated Amide through Alkene Isomerization. Organic Chemistry Frontiers 2018, 5, 1815-1819. Pan, Yixiao; Chen, Changjun; Xu, Xin; Zhao, Haoqiang; Han, Jiahong; Li, Huanrong; Xu, Lijin;* Fan, Qinghua; Xiao, Jianliang, Metal-free Tandem Cyclization/hydrosilylation to Construct Tetrahydroquinoxalines. Green Chemistry 2018, 20, 403-411. Liu, Lingxian; Li, Zengguang; Chen, Changjun; Li, Huanrong; Xu, Lijin;* Yu, Zhiyong, Efficient Dealkylation of Aryl Alkyl Ethers Catalyzed by Cu2O. Tetrahedron 2018, 74, 2447-2453. Zhang, Bo; Mei, Andy R.; Isbell, Mark Antonin; Wang, Dianming; Wang, Yiwei; Tan, Suk F.; Teo, Xsu L.; Xu, Lijin;* Yang, Zhongqiang; Heng, Jerry Y. Y., DNA Origami as Seeds for Promoting Protein Crystallization. ACS Applied Materials & Interfaces 2018, 10, 44240-44246. Zhao, Haoqiang; Xu, Jianbin; Chen, Changjun; Xu, Xin; Pan, Yixiao; Zhang, Zongyao; Li, Huanrong; Xu, Lijin,* Rhodium(III)-Catalyzed Selective Direct Olefination of Imidazoles. Advanced Synthesis & Catalysis 2018, 360, 985-994. Xu, Xin; Zhao, Haoqiang; Xu, Jianbin; Chen, Changjun; Pan, Yixiao; Luo, Zhenli; Zhang, Zongyao; Li, Huanrong; Xu, Lijin,* Rhodium(III)-Catalyzed Oxidative Annulation of 2,2 '-Bipyridine N-Oxides with Alkynes via Dual C-H Bond Activation. Organic Letters 2018, 20, 3843-3847. Zhang, Wen-Wen; Gao, Tao-Tao; Xu, Li-Jin;* Li, Bi-Jie, Macrolactonization of Alkynyl Alcohol through Rh(I)/Yb(III) Catalysis. Organic Letters 2018, 20, 6534-6538. Chen, Changjun; Pan, Yixiao; Zhao, Haoqiang; Xu, Xin; Luo, Zhenli; Cao, Lei; Xi, Siqi; Li, Huanrong; Xu, Lijin,* Ruthenium(II)-Catalyzed Regioselective C-8 Hydroxylation of 1,2,3,4-Tetrahydroquinolines. Organic Letters 2018, 20, 6799-6803. Zhang, Zongyao; Xu, Lijin; Cao, Rui, Structures and Single Crystal to Single Crystal Transformations of Cadmium Frameworks using a Flexible Tripodal Ligand. New Journal of Chemistry 2018, 42, 5593-5601. Dong, Chao-Chen; Xiang, Jun-Feng; Xu, Li-Jin;* Gong, Han-Yuan, From CO2 to 4H‑Quinolizin-4-ones: A One-Pot Multicomponent Approach via Ag2O/Cs2CO3 Orthogonal Tandem Catalysis. J. Org. Chem. 2018, 83, 9561-9567. Dong, Chao-Chen; Xiang, Jun-Feng; Xu, Li-Jin;* Gong, Han-Yuan, MCl4n- (AuCl4-, PtCl42-, or PdCl42-) Anion Extraction from NanMCl4 in Water Using a Tetraimidazolium Macrocyclic Receptor. Tetrahedron Letters 2018, 59, 264-267. Xue, Xiao; Yang, Zhuo; Li, Yanwen; Sun, Pengcheng; Feng, Ya; He, Zhongyu; Qu, Tiejun; Dai, Jian-Guo; Zhang, Tao; Qin, Jie; Xu, Lijin; Zhang, Weidong, Superhydrophobic Self-cleaning Solar Reflective Orange-gray Paint Coating. Solar Energy Materials and Solar Cells 2018, 174, 292-299. Yang, Zhuo; Xue, Xiao; Dai, Jian-guo; Li, Yanwen; Qin, Jie; Feng, Ya; Qu, Jian; He, Zhongyu; Sun, Pengcheng; Xu, Lijin; Zhang, Tao; Qu, Tiejun; Zhang, Weidong, Study of a Super-non-wetting Self-cleaning Solar Reflective Blue-grey Paint Coating with Luminescence. Solar Energy Materials and Solar Cells 2018, 176, 69-80. Zhang, Lingjuan; Gonzalez-de-Castro, Angela; Chen, Changjun; Li, Faju; Xi, Siqi; Xu, Lijin;* Xiao, Jianliang, Iron-catalyzed Cross Etherification of Alcohols to Form Unsymmetrical Benzyl Ethers. Molecular Catalysis 2017, 433, 62-67. Qin, Xubo; Chen, Changjun; Zhang, Lingjuan; Xu, Jianbin; Pan, Yixiao; Zhao, Haoqiang; Han, Jiahong; Li, Huanrong; Xu, Lijin,* Palladium-catalyzed Highly Regioselective and Stereoselective Decarboxylative Arylation of Unactivated Olefins with Aryl Carboxylic Acids. Tetrahedron 2017, 73, 2242-2249. Xue, Xiao; Li, Yanwen; Yang, Zhuo; He, Zhongyu; Dai, Jian-Guo; Xu, Lijin; Zhang, Weidong, A Systematic Investigation of the Waterproofing Performance and Chloride Resistance of a Self-developed Waterborne Silane-based Hydrophobic Agent for Mortar and Concrete. Construction and Building Materials 2017, 155, 939-946. Shen, Meng-Jie; Liang, Tong-Ling; Song, Yue-Qiang; Xu, Li-Jin;* Hao, Xiang; Gong, Han-Yuan, Substrate-induced Adjustment of “Slipped” π–π Stacking: en route to Obtain 1D Sandwich Chain and Higher Order Self-assembly Supramolecular Structures in Solid State. Supramolecular Chemistry, 2017, 29, 24-31.

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