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Select item 25468994
Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.
Littlefield P, Liu L, Mysore V, Shan Y, Shaw DE, Jura N.
Sci Signal. 2014 Dec 2;7(354):ra114. doi: 10.1126/scisignal.2005786.
PMID: 25468994 [PubMed - in process]
Select item 24656791
An ATP-competitive inhibitor modulates the allosteric function of the HER3 pseudokinase.
Littlefield P, Moasser MM, Jura N.
Chem Biol. 2014 Apr 24;21(4):453-8. doi: 10.1016/j.chembiol.2014.02.011. Epub 2014 Mar 20.
PMID: 24656791 [PubMed - indexed for MEDLINE]
Select item 24135280
EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma.
Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA.
Cancer Cell. 2013 Oct 14;24(4):438-49. doi: 10.1016/j.ccr.2013.09.004.
PMID: 24135280 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 24107129
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS.
Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174.
PMID: 24107129 [PubMed - indexed for MEDLINE] Free Article
Select item 24023066
EGFR lung cancer mutants get specialized.
Littlefield P, Jura N.
Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15169-70. doi: 10.1073/pnas.1314719110. Epub 2013 Sep 10. No abstract available.
PMID: 24023066 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 21474065
Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.
Jura N, Zhang X, Endres NF, Seeliger MA, Schindler T, Kuriyan J.
Mol Cell. 2011 Apr 8;42(1):9-22. doi: 10.1016/j.molcel.2011.03.004. Review.
PMID: 21474065 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 20007378
Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3.
Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J.
Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21608-13. doi: 10.1073/pnas.0912101106. Epub 2009 Dec 9.
PMID: 20007378 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 19563760
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.
Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J.
Cell. 2009 Jun 26;137(7):1293-307. doi: 10.1016/j.cell.2009.04.025. Erratum in: Cell. 2009 Aug 7;138(3):604.
PMID: 19563760 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 18046415
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J.
Nature. 2007 Nov 29;450(7170):741-4.
PMID: 18046415 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 17172849
Mapping cellular routes of Ras: a ubiquitin trail.
Jura N, Bar-Sagi D.
Cell Cycle. 2006 Dec;5(23):2744-7. Epub 2006 Dec 1.
PMID: 17172849 [PubMed - indexed for MEDLINE] Free Article
Select item 17087933
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D.
Gastroenterology. 2006 Dec;131(6):1844-55. Epub 2006 Oct 1.
PMID: 17087933 [PubMed - indexed for MEDLINE]
Select item 16507365
Differential modification of Ras proteins by ubiquitination.
Jura N, Scotto-Lavino E, Sobczyk A, Bar-Sagi D.
Mol Cell. 2006 Mar 3;21(5):679-87.
PMID: 16507365 [PubMed - indexed for MEDLINE] Free Article
Select item 15731048
Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis.
Mezyk-Kopec R, Bzowska M, Potempa J, Bzowska M, Jura N, Sroka A, Black RA, Bereta J.
Infect Immun. 2005 Mar;73(3):1506-14.
PMID: 15731048 [PubMed - indexed for MEDLINE] Free PMC Article
Select item 15723087
An ex vivo model for functional studies of myofibroblasts.
Kilarski WW, Jura N, Gerwins P.
Lab Invest. 2005 May;85(5):643-54.
PMID: 15723087 [PubMed - indexed for MEDLINE] Free Article
Select item 15686632
Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between.
Jura N, Archer H, Bar-Sagi D.
Cell Res. 2005 Jan;15(1):72-7. Review.
PMID: 15686632 [PubMed - indexed for MEDLINE] Free Article
Select item 15206946
Tumour necrosis factor-alpha stimulates expression of TNF-alpha converting enzyme in endothelial cells.
Bzowska M, Jura N, Lassak A, Black RA, Bereta J.
Eur J Biochem. 2004 Jul;271(13):2808-20.
PMID: 15206946 [PubMed - indexed for MEDLINE] Free Article
Select item 14597409
Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton.
Kilarski WW, Jura N, Gerwins P.
Exp Cell Res. 2003 Nov 15;291(1):70-82.
PMID: 14597409 [PubMed - indexed for MEDLINE]
Select item 12593796
hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl.
Hall AB, Jura N, DaSilva J, Jang YJ, Gong D, Bar-Sagi D.
Curr Biol. 2003 Feb 18;13(4):308-14.
PMID: 12593796 [PubMed - indexed for MEDLINE]
Select item 10219437
Nasal airway volumetric measurement using segmented HRCT images and acoustic rhinometry.
Dastidar P, Numminen J, Heinonen T, Ryymin P, Rautiainen M, Laasonen E.
Am J Rhinol. 1999 Mar-Apr;13(2):97-103. Erratum in: Am J Rhinol 1999 Jul-Aug;13(4):334. Prasun, D [corrected to Dastidar, P]; Jura, N [corrected to Numminen, J]; Tomi, H [corrected to Heinonen, T]; Pertti, R [corrected to Ryymin, P]; Markus, R [corrected to Rautiainen, M]; Erkki, L [corrected to Laasonen, E].
PMID: 10219437 [PubMed - indexed for MEDLINE]