个人简介
教育经历
9/1990-8/1994: 就读于湖北大学, 获学士学位
9/1994-8/1997: 就读于中国科学院遗传研究所, 获硕士学位
9/2000-8/2003: 就读于加拿大萨斯喀彻温大学, 获硕士学位
9/2003-5/2008: 就读于加拿大萨斯喀彻温大学, 获博士学位
工作经历
9/1997-8/1999:中国科学院遗传研究所研实员
9/1999-8/2000:瑞士Friedrich Miescher 研究所研究助理
4/2008-2/2012:哈佛大学医学院生物化学及分子药理学系博士后
2013-至今: 中国科学院微生物研究所微生物资源前期开发国家重点实验室 研究员
近期论文
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1. Wang Y, Zhang K, Li H, Xu X, Xue H, Wang P, Fu YV(2019) Fine-tuning the expression of target genes using a DDI2 promoter gene switch in budding yeast. Scientific Reports 9(1)
2. Chen Y, Zhan Z, Zhang H, Bi L, Zhang XE, Fu YV(2019) Kinetic analysis of DNA compaction by mycobacterial integration host factor at the single-molecule level. Tuberculosis
3. Xue H, Zhan Z, Zhang K, & Fu YV(2018) Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level. Journal of Visualized Experiments 137
4. Wang J, Ma K, Ruan M, Wang Y, Li Y, Fu YV, Song Y, Sun H, Wang J(2018) A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties. PeerJ
5.Fan Q, Xu X, Zhao X, Wang Q, Xiao W, Guo Y, Fu YV(2018) Rad5 coordinates translesion DNA synthesis pathway by recognizing specific DNA structures in saccharomyces cerevisiae. Current Genetics 64:889-899
6.Xue H, Bei Y, Zhan Z, Chen X, Xu X, Fu YV(2017) Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA-Protein Interactions at the Single-Molecule Level. Front Microbiol 8:2062
7.Zhao X, Liu X, Xu X, Fu YV(2017) Microbe social skill: the cell-to-cell communication between microorganisms. Science Bulletin 62(7):516-524
8.Chen X, Zhao E, Fu YV(2017) Using single-molecule approach to visualize the nucleosome assembly in yeast nucleoplasmic extracts. Science Bulletin 62(6):399-404
9. Zhao D, Chen X, Li K, Fu YV(2017) The application of thermophilic DNA primase TtDnaG2 to DNA amplification. Sci Rep 7(1):12809
10.Wang S, Chen X, Wu W, Chen Z, Du H, Wang X, Fu YV, Hu L, Chen J(2017). Rapid, label-free identification of cerebellar structures using multiphoton microscopy. Journal of Biophotonics 10(12):1617-1626
11.Wang Q, Xue H, Li S, Chen Y, Tian X, Xu X, Xiao W, Fu YV(2017). A method for labeling proteins with tags at the native genomic loci in budding yeast. PloS one 12(5)
12.Zhan Z, Xu X, Fu YV(2016) Single cell tells the developmental story. Science Bulletin 61:1355–1357
13.Xue H, Xu X, Fu YV(2015) New insights in pre-replication complex formation with single-molecule visualization. Science Bulletin 60:1133-1135
14.Fu YV, Yardimci H, Long DT, Ho TV, Guainazzi A, Bermudez VP, Hurwitz J, van Oijen A, Schärer OD, Walter JC (2011) Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell 146(6): 931-941
15.Fu YV and Walter JC (2010) DNA replication: metazoan Sld3 steps forward. Current Biology 20(12): 515-517
16.Fu Y, Zhu Y, Zhang K, Yeung M, Durocher D and Xiao W (2008) Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell 133(4):601-611
17.Fu Y, Pastushok L and Xiao W (2008) DNA damage-induced gene expression in Saccharomyces cerevisiae. FEMS Microbiology Reviews 32(6):908-926
18.Fu Y and Xiao W (2006) Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes. Nucleic Acids Research 34(6):1876-1883
19.Fu Y and Xiao W (2006) Study of transcriptional regulation using a reporter gene assay. Methods in Molecular Biology 313:257-264 Humana Press
20.Wooff J, Pastushok L, Hanna M, Fu Y and Xiao W (2004) The TRAF6 RING finger domain mediates physical interaction with Ubc13. FEBS Letters 566(1-3):229-233