个人简介
学术背景
2000-09--2003-07 中国科学院研究生院/生态环境研究中心 博士
1996-09--1999-07 中国协和医科大学/中国医学科学院药物研究所 硕士
1987-09--1991-07 内蒙古医学院 本科
教授课程
药物分析
科研论文写作
纳米医学和生物传感器
分子与细胞免疫学
药学研究前沿讨论课
文献阅读课
药学前沿讨论课
药物分析原理
微流控芯片实验室在生命科学领域的研究进展
招生专业
071010-生物化学与分子生物学
100704-药物分析学
071009-细胞生物学
招生方向
微流控芯片技术
细胞生物学
药物分析
工作简历
2010-03~现在, 中国科学院大学, 教授
2006-11~2010-02,US EPA National Exposure Research Laboratory, National Research Council Research Associate
2005-01~2006-10,The University of Texas at San Antonio, Postdoctoral Fellow
2003-08~2005-01,北京大学医学部, 讲师
1999-07~2000-08,北京昭衍新药研究中心, 研发人员
1991-07~1996-09,内蒙古医药总公司乌海分公司, 质量管理
奖励信息
(1) 中国分析测试学会科学技术奖, 一等奖, 其他, 2006
(2) Nation Research Council Research Associateship, 其他, 2006
(3) 中科院“地奥”奖, 一等奖, 院级, 2003
专利成果
( 1 ) 分离后可调节pH的微流控芯片电泳-电化学检测装置及其应用, 发明, 2012, 第 1 作者, 专利号: ZL201210286931.3
( 2 ) 一种可机械拉伸的微流控芯片细胞培养装置及其应用, 发明, 2013, 第 1 作者, 专利号: ZL201310043685.3
( 3 ) 体外泡沫细胞形成模型及其在动脉粥样硬化研究中的应用, 发明, 2017, 第 1 作者, 专利号: 201710951234.8
发表著作
(1) 第一章作者 生物分析中的多相微萃取, Solid Phase Microextraction-Advances in Research and Applications, Nova Science Publisher, 2017-11, 第 1 作者
科研项目
( 1 ) 微芯片电泳分离与电化学检测分析氨基糖苷类抗生素方法的研究, 主持, 国家级, 2011-01--2013-12
( 2 ) BR计划支持项目“微流控芯片技术在药物与生物分析中的应用”, 主持, 部委级, 2010-08--2013-12
( 3 ) 中国科学院知识创新工程重要方向项目:生命科学领域“十二五”基础前沿专项, 参与, 部委级, 2011-01--2013-12
( 4 ) 国际创新团队, 参与, 部委级, 2013-12--2016-12
( 5 ) 基于拉伸作用诱导血管内皮细胞炎症反应的血管早期病变过程研究, 主持, 国家级, 2016-01--2019-12
( 6 ) 人工肺泡环境下大气可吸入颗粒物与细胞之间相互作用研究, 主持, 国家级, 2018-01--2021-12
参与会议
(1)微型化生化分析研究与进展 2017中国医师协会检验医师年会 2017-06-16
(2)In vitro methods to evaluate the effect of PM2.5 on human health 2017-05-30
(3)A microfluidic chip with tunable pH for analysis of aminoglycoside antibiotics, 全国微纳流分析会议 Yongsheng Ding 2014-10-30
(4)Microchip with Post Separation Adjustment of pH for Glutathione Analysis Yongsheng Ding 2013-03-21
(5)Investigating the Effect of Unreacted Oligomers on Cell Culturing in Polydimethylsiloxane Microchip 2012第二届分子与细胞生物学大学 Yongsheng Ding Shaozai Zhang Beiyuan Fan 2012-05-18
研究领域
生物力对细胞的作用机制研究;
动脉粥样硬化发生机制研究;
呼吸系统疾病发生机制研究
微流控芯片技术在生物学和药学研究中应用
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
(1) 分散固相萃取结合毛细管电泳-激光诱导荧光法测定血清中甲基化精氨酸, Determination of methylated arginines in serum by a dispersive solid-phase extraction coupled with capillary electrophoresis-laser induced fluorescence detection, 中国科学院大学学报, 2019, 通讯作者
(2) 由可拉伸微流体装置诱导的泡沫细胞形成的体外模型, An in vitro model of foam cell formation induced by a stretchable microfluidic device, Scientific Reports, 2019, 通讯作者
(3) 复合多孔结构改善储存红细胞的流动行为和气体交换, Improved Flowing Behaviour and Gas Exchange of Stored Red Blood Cells by a Compound Porous Structure, Artificial Cells, Nanomedicine and Biotechnology, 2019, 通讯作者
(4) 基于纸张的固相微萃取技术用于CE-LIF分析尿样中的8-羟基-2'-脱氧鸟苷, Paper-based solid-phase microextraction for analysis of 8-hydroxy-2’-deoxyguanosine in urine sample by CE-LIF, Electrophoresis, 2017, 通讯作者
(5) 一种简单的多孔拉伸装置用于诱导血管内皮细胞的炎症反应, A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cell, Lab on a chip, 2016, 通讯作者
(6) 一种通过胶束电动色谱法筛选β2-激动剂的新方法, A new method for screening of beta2-agonists by micellar electrokinetic chromatography, 中国科学院大学学报, 2015, 通讯作者
(7) 基于微芯片电泳-电化学方法的细胞内谷胱甘肽分析, Analysis of glutathione in cells by microchip electrophoreesis coupled with electrochemical detection, 中国科学院大学学报, 2014, 通讯作者
(8) CE-LIF测定尿中4-氯-7-硝基苯并呋喃衍生的8-羟基-2-脱氧鸟苷, Determination of 8-hydroxy-2- deoxyguanosine derivatized with 4-chloro-7- nitrobenzofurazan in urine by CE-LIF, Electrophoresis, 2014, 通讯作者
(9) 用微芯片调节分离后pH值用于氨基糖苷类抗生素分析的研究, Study of the post separation pH adjustment by a microchip for the analysis of aminoglycoside antibiotics, RSC Adv., 2014, 通讯作者
(10) 环糊精修饰金纳米粒子毛细管电色谱在线样品堆积同时和灵敏测定氨基苯甲酸异构体, A Cyclodextrin-Modified Gold Nanoparticle Capillary Electrochromatography with Online Sample Stacking for Simultaneous and Sensitive Determination of Aminobenzoic Acid Isomers, Chromatographia, 2014, 第 6 作者
(11) 图解纸芯片制作及应用进展, Illustrated development on the fabrication and applications of paper-based microfluidics, 现代仪器与医疗, 2013, 通讯作者
(12) 微脉冲胶束电动色谱 - 脉冲电化学检测法快速测定尿样中β2-激动剂, Rapid determination of β2-agonists in urine samples by microchip micellar electrokinetic chromatography with pulsed electrochemical detection, Analytical Methods, 2013, 通讯作者
(13) pH值的分离后调整使得能够通过微安培电泳和安培检测分析氨基糖苷类抗生素, Post separation adjustment of pH to enable the analysis of aminoglycoside antibiotics by microchip electrophoresis with amperometric detection, Electrophoresis, 2012, 通讯作者
(14) 微流控芯片技术在细胞生物学研究中的应用进展, Recent Applications of Microfluidic Technology in the Field of Cell Biology, 中国细胞生物学学报, 2011, 通讯作者
(15) Determination of haloacetic acids in water using solid-phase extraction/microchip using solid-phase extraction/microchip coupled contactless conductivity detection, Electrophoresis, 2010, 第 1 作者
(16) Measurement of Nitrogen Mustards Degradation Products by Poly(dimethylsiloxane) Microchip Electrophoresis with Contactless Conductivity Detection, Electroanalysis, 2008, 第 1 作者
(17) Poly(dimethylsiloxane) Microchip Electrophoresis with Contactless Conductivity Detection for Measurment of Chemical Warfare Agent Degradation Products, Analytical Letters, 2008, 第 1 作者
(18) The effects of alkyl sulfates on the analysis of phenolic compounds by microchip capillary electrophoresis with pulsed amperometric detection, Analyst, 2007, 第 1 作者
(19) Electrochemical detection of phenolic compounds using cylindrical carbon-ink electrodes and microchip capillary electrophoresis, Analytica Chimica Acta, 2007, 第 1 作者
(20) Determination of banned sudan dyes in chili powder by capillary electrophoresis, Food Chemistry, 2007, 第 2 作者
(21) Application of microchip-CE electrophoresis to follow the degradation of phenolic acids by aquatic plants, Electrophoresis, 2006, 第 1 作者
(22) Determination of Nonsteroidal Anti-Inflammatory Drugs in Serum by Microchip Capillary Electrophoresis with Electrochemical Detection, Electroanalysis, 2006, 第 1 作者
(23) Analysis of alkyl gallates and nordihydroguaiaretic acid using plastic capillary electrophoresis, Analytica Chimica Acta, 2006, 第 1 作者
(24) Pulsed amperometric detection with poly(dimethylsiloxane)-fabricated capillary electrophoresis for the determination of EPA priority pollutants, Analyst, 2006, 第 1 作者
(25) Optimizing the quadruple-potential waveform for the pulsed amperometric detection of neomycin, Journal of Chromatography A, 2004, 第 1 作者
(26) Off-line elimination of carbohydrates for amino acid analysis of samples with high carbohydrate content by ion-exchange chromatography, Journal of Chromatography A, 2003, 第 1 作者
(27) Some factors affecting separation and detection of amino acids by high-performance anion-exchange chromatography with integrated pulsed amperomeric detection, Journal of Chromatography A, 2003, 第 2 作者
(28) Direct and simultaneous determination of amino acids and sugars in rice wine by high-performance anion-exchange chromatography with integrated pulsed amperometric detection, Chromatographia, 2003, 第 2 作者
(29) Direct determination of free amino acids and sugars in green tea by anion exchange chromatography with integrated pulsed amperometric detection, Journal of Chromatography A, 2002, 第 1 作者
(30) Effects of common metal ions on the determination of anions by suppressed ion chromatography, Journal of Chromatography A, 2002, 第 1 作者
(31) Effects of common metal ions on the determination of anions by suppressed ion chromatography, Journal of Chromatography A, 2002, 第 1 作者
(32) Simultaneous determination of amino acids and carbohydrates by anion-exchange chromatography with integrated pulsed amperometric detection, Journal of Chromatography A, 2002, 第 2 作者