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个人简介

教育经历 2002-2006三峡大学生物学,学士 2006-2009三峡大学生物学,硕士 2009-2013中国科学院遗传与发育生物学研究所,博士 工作经历 2013-今信阳师范学院生命科学学院 教学情况: 主讲《细胞生物学专题》和《分子生物学》等本科生课程。 获资助项目: 参与国家自然科学基金面上项目。

研究领域

1.乳腺癌干细胞三维培养体系建立; 2.注射型胶原支架材料的制备; 3.有序性胶原支架材料应用于脊髓损伤修复。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.ZhengquanHe,LeiChen,WeiYao,JianwuDai.RecentProgressinCucumber(Cucumissativus)Transformation.TransgenicPlantJournal,2008,2:39-44(co-first-author). 2.LeiChen,ZhengquanHe,BingChen,YannanZhao,WenjieSun,ZhifengXiao,JingZhang,MaojinYang,ZhiyingGao,andJianwuDa.DirectChemicalCross-LinkingofPlatelet-DerivedGrowthFactor-BBtotheDemineralizedBoneMatrixImprovesCellularizationandVascularization.Biomacromolecules,2009,10,3193–3198(IF=5.479). 3.LeiChen,ZhengquanHe,BingChen,MaojinYang,YannanZhao,WenjieSun,ZhifengXiao,JingZhang,JianwuDai.LoadingofVEGFtotheheparincross-linkeddemineralizedbonematriximprovesvascularizationofthescaffold.JMaterSci:MaterMed,2010,21:309–317(IF=2.316). 4.LeiChen,ZhifengXiao,YueMeng,YannanZhao,JinHan,GuannanSu,BingChen,JianwuDai.TheenhancementofcancerstemcellpropertiesofMCF-7cellsin3Dcollagenscaffoldsformodelingofcancerandanti-cancerdrugs.Biomaterials,2012,33:1437-1444(IF=7.404). 5.陈磊,何正权,杨晔,姚伟.植物遗传转化的正向选择标记.中国生物工程杂志,2008,28(6s):283-288. 6.JinHan,ZhifengXiao,LeiChen,BingChen,XiaoranLi,SufangHan,YannanZhao,JianwuDai.Maintenanceoftheself-renewalpropertiesofneuralprogenitorcellsculturedinthree-dimensionalcollagenscaffoldsbytheREDD1-mTORsignalpathway.Biomaterials.2013,34(8):1921-8. 7.QinShi,YangLi,JieSun,HuaZhang,LeiChen,BingChen,HuilinYang,ZhaoxuWang.Theosteogenesisofbacterialcellulosescaffoldloadedwithbonemorphogeneticprotein-2.Biomaterials.2012,33(28):6644–6649 8.QianqianHan,WeiJin,ZhifengXiao,HongbinNi,JinhuanWang,JieKong,JunWu,WeibangLiang,LeiChen,YannanZhao,BingChen,JianwuDai.ThepromotionofneuralregenerationinanextremeratspinalcordinjurymodelusingacollagenscaffoldcontainingacollagenbindingneuroprotectiveproteinandanEGFRneutralizingantibody.Biomaterials.2010,31(35):9212–9220 9.QifenHe,YannanZhao,BingChen,ZhifengXiao,JingZhang,LeiChen,WeiChen,FeilongDeng,JianwuDai.Improvedcellularizationandangiogenesisusingcollagenscaffoldschemicallyconjugatedwithvascularendothelialgrowthfactor.ActaBiomaterialia.2011,7(3):1084–1093 10.GuannanSu,YannanZhao,JianshuWei,JinHan,LeiChen,ZhifengXiao,BingChen,JianwuDai.Theeffectofforcedgrowthofcellsinto3Dspheresusinglowattachmentsurfacesontheacquisitionofstemnessproperties.Biomaterials.2013,34(13):3215–3222 11.SufangHan,YannanZhao,ZhifengXiao,JinHan,BingChen,LeiChen,JianwuDai.TheThree-DimensionalCollagenScaffoldImprovestheStemnessofRatBoneMarrowMesenchymalStemCells.JournalofGeneticsandGenomics.2012,39(12):633–641 12.XiaoranLi,ZhifengXiao,JinHan,LeiChen,HanshanXiao,FukaiMa,XianglinHou,XingLi,JieSun,WenyongDing,YannanZhao,BingChen,JianwuDai.PromotionofneuronaldifferentiationofneuralprogenitorcellsbyusingEGFRantibodyfunctionalizedcollagenscaffoldsforspinalcordinjuryrepair.Biomaterials,2013,34(21):5107–5116. 13.JianGuan,ZhaohuiZhu,RobertChunhuaZhao,ZhifengXiao,ChenxiWu,QinHan,LeiChen,WeiminTong,JinZhang,QianqianHan,JunGao,MingFeng,XinjieBao,JianwuDai,RenzhiWang.Transplantationofhumanmesenchymalstemcellsloadedoncollagenscaffoldsforthetreatmentoftraumaticbraininjuryinrats.Biomaterials,2013,34(24):5937–5946. 14.JinHan,LeiChen,GuanzhengLuo,BinDai,XiujieWang,JianwuDai.Three-dimensionalculturemaypromotecellreprogramming.Organogenesis,2013,9(2):118-120 15.GuannanSu,YannanZhao,JianshuWei,ZhifengXiao,BingChen,JinHan,LeiChen,JianGuan,RenzhiWang,QunDong,JianwuDai.Directconversionoffibroblastsintoneuralprogenitor-likecellsbyforcedgrowthinto3Dspheresonlowattachmentsurfaces.Biomaterials,2013,34(24):5897–5906

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