研究领域
通过将合成化学，高分子物理和分子生物相结合，我们设计和执行决定性的实验来回答与大分子，生物以及胶体有关的
重要问题，包括，
1. 分子药物非病毒载体的设计与研发
2. 与神经退化型疾病有关的蛋白聚集的成核过程
3. 功能性大分子的设计，合成和自组裝
4. 大分子溶液和凝胶网络的动力学与结构
5. 难解和特殊高分子的分子特性
近期论文
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Chi Wu,Shuiqin Zhou,“light-scattering study of the phase transition of poly(N-isopropyl-acrylamide) in water: I.single chain”Macromolecule-s,28,8381(1995)
Chi Wu, Shuiqin Zhou,“First Observation of the Molten Globule State of a Single Homopolymer Chain”,Physics Review Letters,77(14),3053 (1996)
Chi Wu,Xiaohui Wang,“Globule-to-coil transition of a single homopolymer chain in solution”,Physical Review Letters,80(18),4092(1998)
Chi Wu,Zuowei Xie,Guangzhao Zhang,Guofu Zi,Yingfeng Tu,Yali Yang,Ping Cai and Ting Nie,“Self-assembly assisted polymerization(SAAP): approaching long multi-block copolymers with an ordered chain sequence and controllable block length”,Chem.Commun,23,2898(2002)
Fan Jin,Chi Wu,“Observation of the first-order transition in ultra-filtration of flexible linear polymer chains”,Physical Review Letters,96,237801(2006)
Kejin Zhou,Yijie Lu,Junfang Li,Lei Shen, Guangzhao Zhang, Zuowei Xie and Chi Wu, “The coil-to-globule-to-coil transition of linear polymer ch -ains in dilute aqueous solutions: Effect of intrachain hydrogen bonding”, Macromolecules, 41, 8927-8931 (2008)
Rui Deng,Yanan Yue,Fan Jin,Yangchao Chen,Hsiang-Fu Kung,Marie C.M.Lin,Chi Wu,“Revisit the complexation of PEI and DNA — How to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?”Journal of Controlled Release,140,40-46(2009)(Cover Story)
Hui Ge,Chi Wu,“Separation of linear and star chains by a nanopore”Macromolecules,43,8711-8713(2010)
Yanan Yue,Fan Jin,Rui Deng,Jinge Cai,Yangchao Chen,Marie C.M.Lin,Hsiang-Fu Kung and Chi Wu,“Revisit complexation between DNA and polyethylenimine-Effect of uncomplexed chains free in the solution mixture on gene transfection”,Journal of Controlled Release,155, 67–76(2011)
Chi Wu,“Why RNA and Protein Chains are Linear and not Colliding inside Nuclear Pores”,Macromolecules,45,4422-4424 (2012)
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