赵铁军 - 浙江师范大学 - 化学与生命科学学院

研究领域

1. 肿瘤发生的分子机制研究 2. 抗肿瘤药物的开发和应用评价 3. 肿瘤细胞信号转导与基因调控 1. 生物化学与分子生物学 2. 基础医学 3. 细胞生物学

近期论文

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Tiejun Zhao, Yorifumi Satou, Kenji Sugata, Patrick L. Green, Takeshi Imamura, Masao Matsuoka. Human T-cell leukemia virus type 1 bZIP factor enhances TGF-beta signaling through p300 coactivator. Blood. 2011;118 (7):1865-1876. (IF=10.555) Tiejun Zhao, Jun-ichirou Yasunaga, Yorifumi Satou, Mitsuyoshi Nakao, Masahiko Takahashi, Masahiro Fujii, Masao Matsuoka. Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. Blood. 2009;113 (12):2755-2764. (IF=10.555) Tiejun Zhao*, Aaron Coutts, Lingling Xu, Juntao Yu, Koichi Ohshima, Masao Matsuoka. HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPalpha signaling. Retrovirology. 2013 Dec 21;10(1):159. (*corresponding author) (IF=6.470) Tiejun Zhao*, Yorifumi Satou, and Masao Matsuoka. Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice. Arch Virol. 2014 Jul;159(7):1849-56 (*corresponding author) (IF=2.111) Tiejun Zhao, Masao Matsuoka. HBZ and its roles in HTLV-1 oncogenesis. Front Microbiol. 3:247. doi:10.3389/fmicb.2012.00247. (IF=3.941) Michi Miura, Jun-ichirou Yasunaga, Junko Tanabe, Kenji Sugata, Tiejun Zhao, Guangyong Ma, Paola Miyazato, Koichi Ohshima, Akihisa Kaneko, Akino Watanabe, Akatsuki Saito, Hirofumi Akari, Masao Matsuoka. Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection. Retrovirology. 2013 Oct 24;10(1):118. Yorifumi Satou, Jun-ichirou Yasunaga, Tiejun Zhao, Mika Yoshida, Paola Miyazato, Ken Takai, Kei Shimizu, Koichi Ohshima, Patrick L. Green, Naganari Ohkura, Tomoyuki Yamaguchi, Masahiro Ono, Shimon Sakaguchi, Masao Matsuoka. HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. PLoS Pathog. 7(2): e1001274. doi:10.1371/journal.ppat.1001274. Ling Qiao, Zhili Xu, Tiejun Zhao, Zhigang Zhao, Mingxia Shi, Robert Zhao, Lihong Ye, Xiaodong Zhang. Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model. Cell Res. 2008;18(4):500-7. Ling Qiao, Zhi-li Xu, Tie-jun Zhao, Li-hong Ye, Xiao-dong Zhang. Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett. 2008;269(1):67-77. Hong Hui Wang, Hideyuki Tanaka, Xiaoran Qin, Tiejun Zhao, Lihong Ye, Tuyoshi Okagaki, Takeshi Katayama, Akio Nakamura, Ryoki Ishikawa, Sean E. Thatcher, Gary L. Wright, Kazuhiro Kohama. Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells through breaking the interaction between myosin II and actin. Am J Physiol Heart Circ Physiol. 2008;294(5):H2060-8. Ling QIAO, Tie-jun ZHAO, Feng-ze WANG, Chang-liang SHAN, Li-hong YE, Xiao-dong ZHANG. NF-kappaB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells. Acta Pharmacol Sin. 2008;29(3):333-40.