个人简介

Born Israel, 1973. ORT Braude Academic College of Engineering, B.Tech., 2000. The Hebrew University of Jerusalem, Israel, M.Sc, 2002. The Hebrew University of Jerusalem, Israel, PH.D., 2007. Massachusetts Institute of Technology, Postdoctoral Associate, 2008-2011. University of Chicago, Assistant Professor, starting July 2011. Accolades 2006 The Rudolf Graf Prize in Excellence, The Hebrew University of Jerusalem. 2006 The Johanna Friedlander Memorial Prize in Excellence, The Hebrew University of Jerusalem. 2004 The Kaye Award for Innovations, The Hebrew University of Jerusalem. 2000 Diploma with Honors, ORT Braude Academic College of Engineering. 1997-1999 Dean’s List of undergraduate outstanding students, ORT Braude Academic College of Engineering.

研究领域

Organic Chemistry/Chemical Biology/Materials/Nanoscience

Nanoscience offers unparalleled opportunities for designing ground-breaking generations of medical diagnostics and research platforms. Research in the Weizmann laboratory is based on a multidisciplinary field interfacing with biology, chemistry, nanotechnology and materials science, where large research directions take place. My group will focus on new ways to improve our ability to manipulate DNA, to develop remarkable and desired functional structures and superior sensors that can be controlled upon demand. My research interests are concerned with the application of nanowire based electronic/optical devices in the biological and chemical detection area, with the aim of exploring and exploiting the nanoscale advantages in the world of material chemistry, to address significant chemical, biochemical and technological problems. One of the central themes of my research program is to approach nanoscience from a multidisciplinary perspective by integrating biomaterials (nucleic acids and proteins), inorganic materials, carbon nanotubes and small molecules via non-covalent and covalent interactions, to develop new hybrid materials with emergent properties. My objective is to establish a fascinating and attractive interdisciplinary field that can join students, post-docs and researchers from different science areas. I believe that the multidisciplinary emphasis of my research will create an atmosphere of varied and collaborative work that will stimulate the students’ motivation and promote their independence and ability to explore new and challenging areas.

近期论文

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G. Chen, D. Liu, C. He, T. Gannett, W. Lin and Y. Weizmann. Enzymatic Synthesis of Periodic DNA Nanoribbons for Intracellular pH Sensing and Gene Silencing. J. Am. Chem. Soc., Article ASAP (2015). L. Tian, Timothy M. Cronin and Y. Weizmann. Enhancing-Effect of Gold Nanoparticles on DNA Strand Displacement Amplifications and its Application to an Isothermal Telomerase Assay. Chem. Sci., 5, 4153-4162 (2014). Invited Cover Art: Selected as the outside front cover for the issue 11 of Chemical Science L. Tian and Y. Weizmann. Real-Time Detection of Telomerase Activity Using the Exponential Isothermal Amplification of Telomere Repeat Assay. J. Am. Chem. Soc., 135, 1661-1664 (2013). J. M. Schnorr, D. v. d. Zwaag, J. J. Walish, Y. Weizmann and T. M. Swager. Sensory Arrays of Covalently Functionalized Single-Walled Carbon Nanotubes for Explosive Detection. Adv. Funct. Mater., 23, 5285-5291 (2013). Y. Weizmann, D. M. Chenoweth and T. M. Swager. DNA-CNT Nanowire Networks for DNA Detection. J. Am. Chem. Soc., 133, 3238-3241 (2011). Y. Weizmann, D. M. Chenoweth and T. M. Swager. Addressable Terminally-Linked DNA-CNT Nanowires. J. Am. Chem. Soc., 132, 14009-14011 (2010). Y. Weizmann, J. Lim, D. M. Chenoweth, and T. M. Swager. Regiospecific Synthesis of Au-Nanorod/SWCNT/Au-Nanorod Heterojunctions. Nano lett., 10, 2466-2469 (2010). O. I. Wilner, S. Shimron, Y. Weizmann, Z-G. Wang, and I. Willner. Self-Assembly of Enzymes on DNA Scaffolds: En Route to Biocatalytic Cascades and the Synthesis of Metallic Nanowires. Nano lett., 9, 2040-2043 (2009). O. I. Wilner, Y. Weizmann, R. Gill, O. Lioubashevski, R, Freeman and I. Willner. Enzyme cascades activated on topologically programmed DNA scaffolds. Nature nanotechnology, 4, 249-255 (2009). (Cited 150+ times) Nature Nanotechnology 4, 211-212 (April 2009) doi:10.1038/nnano.2009.66 News and Views Nature Chemistry (9 April 2009) doi:10.1038/nchem.210 Y. Weizmann, Z. Cheglakov and I. Willner. A Fok I/DNA Machine that Duplicates its Analyte Gene Sequence. J. Am. Chem. Soc., 130, 17224-17225 (2008). Y. Weizmann, A. B. Braunschweig, O. I. Wilner, Z. Cheglakov and I. Willner. Supramolecular aptamer–thrombin linear and branched nanostructures. Chem. Commun., 4888-4890 (2008). Z. Cheglakov, Y. Weizmann, E. Sharon and I. Willner. Analysis of DNA and single-base mutations using magnetic particles for purification, amplification and DNAzyme detection. Analyst, 133, 923-927 (2008). Y. Weizmann, A. B. Braunschweig, O. I. Wilner, Z. Cheglakov and I. Willner. A polycatenated DNA scaffold for the one-step assembly of hierarchical nanostructures. PNAS, 105, 5289-5294 (2008). Z. Cheglakov, Y. Weizmann, A. B. Braunschweig, O. I. Wilner and I. Willner. Increasing the Complexity of Periodic Protein Nanostructures by the Rolling-Circle-Amplified Synthesis of Aptamers. Angew. Chem. Int. Ed., 47, 126-130 (2008). B. Shlyahovsky, D. Li, Y. Weizmann, R. Nowarski, M. Kotler and I. Willner. Spotlighting of Cocaine by an Autonomous Aptamer-Based Machine. J. Am. Chem. Soc., 129, 3814-3815 (2007). (Cited 150+ times) M. K. Beissenhirtz, R. Elnathan, Y. Weizmann and I. Willner. The Aggregation of Au Nanoparticles by an Autonomous DNA Machine Detects Viruses. Small, 3, 375-379 (2007). Z. Cheglakov, Y. Weizmann, B. Basnar and I. Willner. Diagnosing Viruses by the Rolling Circle Amplified Synthesis of DNAzymes. Org. Biomol. Chem., 5, 223-225 (2007). One of the most cited and downloaded papers published in OBC for the year 2007 Y. Weizmann, M. K. Beissenhirtz, Z. Cheglakov, R. Nowarski, M. Kotler and I. Willner. A Virus Spotlighted by an Autonomous DNA Machine. Angew. Chem. Int. Ed., 45, 7384-7388 (2006). (Cited 150+ times) Nature News: doi:10.1038/news061106-19 Jianping. X, Y. Weizmann, N. Krikhely, R. Baron and I. Willner. Layered Hydrogen-Bonded Nucleotide-Functionalized CdS Nanoparticles for Photoelectrochemical Applications. Small, 2, 1178-1182 (2006). Z. Cheglakov, Y. Weizmann, Moritz K. Beissenhirtz and I. Willner. Ultrasensitive Detection of DNA by the PCR-Induced of DNAzymes: The DNAzyme Primer Approach. Chem. Commun., 3205-3207 (2006). Y. Weizmann, Z. Cheglakov, V. Pavlov and I. Willner. An Autonomous Fueled Machine that Replicates Catalytic Nucleic Acid Templates for the Amplified Optical Analysis of DNA. Nature Protocols, 1, 554-558 (2006).