研究领域
不对称催化化学
主要应用均相的或者非均相的手性催化剂催化前手性的底物，以获得大量的手性化合物。以手性的含氮和膦为配体研究不对称的氢化反应、取代反应。从不同的角度研究手性催化剂化学选择性和立体选择性。研究反应规律、反应机理，特别是反应的对映选择性进行研究。目前在进行以有机磷为配体手性催化剂进行催化氢化反应和氢硅化反应。
近期论文
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Xinsheng Li*, Qing Li, Xiaohua Wu,Yongguang Gao, Dongcheng Xu, Lichun Kong，Enantioselective hydrogenation of olefins with planar chiral iridium ferrocenyloxazolinylphosphine complexes. Tetrahedron: Asymmetry 2007, 18, 629-634.
Xinsheng Li*, Lichun Kong, Yongguang Gao, Xiaoxia Wang, Enantioselective hydrogenation of olefins with axial chiral iridium QUINAP complex. Tetrahedron Lett. 2007, 48, 3915-3917.
Xinssheng Li*, Xiangyan Meng, Hong Su, Xiaohua Wu Dongcheng Xu, A novel chiral H'4-NOBIN Schiff base for hetero-Diels-Alder reaction of Danishefsky's diene with aldehydes Synlett 2008，857-860.
Xinsheng Li* Jianan Song, Dongcheng Xu, Lichun Kong Asymmetric hydrosilylation of styrenes using new chiral phosphoramidites, synthesis, 2008, 925-931.
Xinsheng Li*, Qianchang Ding, Jianfeng Ge, Jianwu Xie, Dongcheng Xu. A Convenient Synthesis of (S)-H4-BINOL and Its Derivatives via Hydrogenation of Monoesters of BINOL. J. Org. Chem., 2009, 74, 1785.
Meng Xiangyan, Gao Yongguang, LI Xin-Sheng*, XU Dong-Cheng. Novel pyridine-phosphite ligands for Pd-catalyzed asymmetric allylic substitution reaction. Catal. Commun. 2009, 10, 950-954.
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