林旭锋 - 浙江大学

个人简介

2007年-至今，浙大化学系教师,有机化学硕导(2007)课题组长博导(2012)。 2010-2011年，斯坦福大学化学系Barry M. Trost教授组访问学者； 2005-2006年，浙江大学学科博士后、助理研究员； 2000-2005年，博士毕业于浙江大学化学专业； 1996-2000年，本科毕业于浙江大学化学专业； 1977年，出生于浙江省慈溪市；

研究领域

从事有机合成方法学研究，注重新型手性配体和催化剂的设计、合成和在手性药物及其中间体合成中的应用研究；

近期论文

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Jun Luo; T. Zhang; L. Wang; G. Liao; Q. Yao; Y. Wu; B. Zhan; Yu. Lan*; Xufeng. Lin*; Bingfeng Shi*, Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C–H Olefination using Chiral Spiro Phosphoric Acid Ligands, Angew. Chem., Int. Ed. 2019, doi.org/10.1002/anie.201902126. Chuan He; Jun Xuan; Peirong Rao; Xufeng Lin*; Hanfeng Ding*, Total Syntheses of (+)-Sarcophytin, (+)-Chatancin, (‒)-3-Oxochatancin, and (‒)-Pavidolide B: A Divergent Approach, Angew. Chem., Int. Ed. 2019, 58, 5100-5104. Haorui Gu, Shaoying Huang, Xufeng Lin*, Iron-catalyzed asymmetric intramolecular cyclopropanation reactions using chiral tetramethyl-1,1′-spirobiindane-based bisoxazoline (TMSI-BOX) ligands, Org. Biomol. Chem. 2019, 17, 1154-1162. Zhou, Qiaoxia; Rihuang Pan, Huanyu Shan, Xufeng Lin*,Synthesis and Optical Resolution of 3,3,3',3'-Tetramethyl-1,1'-spirobiindane-7,7'-diol, Synthesis, 2019, 51, 557-563. Haorui Gu, Zhao Han, Hujun Xie,* Xufeng Lin*, Iron-Catalyzed Enantioselective Si–H Bond Insertions. Org. Lett., 2018, 20, 6544-6549. Huanyu Shan, Rihuang Pan, Xufeng Lin*, Synthesis and Application of A New Chiral Monodentate Spiro Phosphoramidite Ligand Based on Hexamethyl-1,1’-spirobiindane Backbone in Asymmetric Hydroamination/arylation of Alkenes. Org. Biomol. Chem., 2018, 16, 6183-6186. Huanyu Shan, Zhou, Qiaoxia; Yu, Jinglu; Zhang, Shuoqing; Hong, Xin*; Xufeng Lin*, Rhodium-Catalyzed Asymmetric Addition of Organoboronic Acids to Aldimines Using Chiral Spiro Monophosphite-Olefin Ligands: Method Development and Mechanistic Studies, J. Org. Chem., 2018, 83, 11873-11885. W. Sun, H. Gu, Xufeng. Lin*, Synthesis and Application of Hexamethyl-1,1′-spirobiindane-Based Phosphine-Oxazoline Ligands in Ni-Catalyzed Asymmetric Arylation of Cyclic Aldimines. J. Org. Chem., 2018, 83, 4034–4043. A. Rahman, Xufeng Lin*, The development and application of chiral spirocyclic phosphoric acids in asymmetric catalysis, Org. Biomol. Chem., 2018, 16, 4753-4777. A. Rahman, Q. Zhou, Xufeng Lin*, Asymmetric Organocatalytic Synthesis of Chiral 3,3-Disubstituted Oxindoles via 1,6-Conjugate Addition Reaction, Org. Biomol. Chem., 2018, 16, 5301-5309. S. Chang, L. Wang, Xufeng Lin*, Synthesis and Application of A New Hexamethyl-1,1’-spirobiindane-based Chiral Bisphosphine (HMSI-PHOS) Ligand in Asymmetric Allylic Alkylation, Org. Biomol. Chem., 2018, 16, 2239 - 2247. A. Rahman, E. Xie, Xufeng Lin*, Organocatalytic asymmetric synthesis of benzazepinoindole derivatives with trifluoromethylated quaternary stereocenters by chiral phosphoric acid catalysts. Org. Biomol. Chem., 2018,16, 1367-1374. Lei Wang, Abdul Rahman, Xufeng Lin* , Enantioselective synthesis of cyclic quaternary α-amino acid derivatives by chiral phosphoric acid catalysis. Org. Biomol. Chem., 2017,15, 6033-6041. En Xie, Abdul Rahman, Xufeng Lin*, Asymmetric synthesis of CF3- and indole-containing tetrahydro-β-carbolines via chiral spirocyclic phosphoric acid-catalyzed aza-Friedel–Crafts reaction, Org. Chem. Front., 2017,4, 1407-1410. Hengqiao Lou, Yongtao Wang, Enze Jin, Xufeng Lin* , Organocatalytic Asymmetric Synthesis of Dihydrobenzoxazinones Bearing Trifluoromethylated Quaternary Stereocenters,J. Org. Chem., 2016, 81 (5), pp 2019–2026. Zhenjun Mao, Fan Mo, Xufeng Lin*，Diastereo- and enantioselective assembly of spirooxindole tetrahydroquinoline skeletons via asymmetric binary acid catalyzed hydride transfer-cyclization, Synlett 2016; 27(04): 546-550, Cluster topic: "Asymmetric Phosphoric Acid Catalysis" [Invitation] Xiaoming Shen, Yongtao Wang, Tiandi Wu, Zhenjun Mao, Xufeng Lin*，Triply Hydrogen-Bond-Directed Enantioselective Assembly of Pyrrolobenzo-1,4-diazine Skeletons with Quaternary Stereocenters, Chem. Eur. J. 2015, 21，9039-9043. Xuejian Li, Di Chen, Haorui Gu, Xufeng Lin*，Enantioselective Synthesis of Benzazepinoindoles Bearing Trifluoromethylated Quaternary Stereocenters Catalyzed by Chiral Spirocyclic Phosphoric Acids, Chem.Commun. 2014, 50,7538-7541. Haijun Qu, Xuejian Li, Fan Mo, Xufeng Lin*，Efficient Synthesis of dihydropyrimidinones via three-component Biginelli-type reaction of urea, alkyl aldehyde, and aryl aldehyde, Beilstein J. Org. Chem. 2013, 9， 2846-2851. [Invitation] Dan Huang, Xuejian Li, Fangxi Xu, Luhang Li, Xufeng Lin*，Highly Enantioselective Synthesis of Dihydroquinazolinones Catalyzed by SPINOL-Phosphoric Acids, ACS Catalysis 2013, 3, 2244-2247.