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研究领域

1. 高新材料(纳米材料,铁基超导材料等)的结构分析( 采用Atomic Pair Distribution Function 方法分析材料的结构); 2. 药物化学及分析:具有生物活性配体的配位化学及抗肿瘤药物研究; 3. 磁共振波谱学(NMR & EPR)及其在材料、生物等方面的应用等。

近期论文

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Poly[[(N,N-dimethylformamide-O)(3-pyrazine-2,3-dicarboxylato-4N1,O2:O3:O3)copper(II)] monohydrate], Acta Cryst., E 66: M10-U226 , 2010. Poly[aqua[2-cis-1,2-bis(4-pyridyl)ethylene-2N:N'](2-5-nitroisophthalato-3O:O',O'')nickel(II)], Acta Cryst., E 66: M80-U866 , 2010. Predicting blood-brain barrier penetration from molecular weight and number of polar atoms, European Journal of Pharmaceutics and Biopharmaceutics, 70(2): 462-466, 2008. Synthesis, Spectral Analysis, Antibacterial and Antitumor Activities of Co(II) and Ni(II) Ofloxacin Complexes, Spectroscopy and Spectral Analysis, 28(10): 2388, 2008. Divalent ytterbium boratabenzene complex (C5H5BNPh2)2Yb(THF)2: Synthesis, structure, and solvent-mediated redox transformation, Organometallics, 27 (15): 4013-4016, 2008. Interaction between Pazufloxacin and DNA mediated by copper (II) ions, Journal of Fluorescence, 18 ( 3-4) : 701-706, 2008. Prediction of plasma protein binding of cephalosporins using an artificial neural network, Pharmazie, 62 (2): 157-158 2007. Synthesis, crystal structure, antibacterial and antitumor activities of a new Cadmium(II)-ciprofloxacin ionic compound, CHINESE JOURNAL OF INORGANIC CHEMISTRY 21 (9): 1363-1366 SEP 2005 Prediction of human intestinal absorption using an artificial neural network, PHARMAZIE 60 (9): 674-676 SEP 2005 A mathematical model to predict the release of water-soluble drugs from HPMC matrices, PHARMAZIE 59 (9): 706-708 SEP 2004 A predictive model for the release of slightly water-soluble drugs from HPMC matrices, PHARMAZIE 59 (8): 624-626 AUG 2004 Limitation of Potts and Guy's model and a predictive algorithm for skin permeability including the effects of hydrogen-bond on diffusivity, PHARMAZIE 59 (4): 282-285 APR 2004 Prediction of drug release from HPMC matrices: effect of physicochemical properties of drug and polymer concentration, JOURNAL OF CONTROLLED RELEASE 95 (2): 209-216 MAR 5 2004 Predicting blood-brain barrier penetration of drugs using an artificial neural network, PHARMAZIE 59 (2): 126-130 FEB 2004 Synthesis, crystal structure and antitumor activity of mixed ligand coordination compound of copper with norfloxacin and 1,10-phen, [Cu(NFLX)(phen)(H2O)] NO3 center dot 3H(2)O, CHINESE CHEMICAL LETTERS 14 (11): 1182-1184 NOV 2003 Synthesis, crystal structure, antibacterial and antitumor activities of a new binuclear copper(II) complex with 1,10-phen and fluoroquinolone, CHINESE JOURNAL OF INORGANIC CHEMISTRY 19 (9): 1001-1005 SEP 2003 Crystal structure of (1-cyclopropyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylato)chloro(2,2 '-bipyridine)copper(II) dihydrate, CuCl(C10H8N2)(C13H8NClFO3)center dot 2H(2)O , ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 218 (2): 245-246 2003 Influence of drug solubility on the release of slightly water-soluble drugs from HPMC matrices, PHARMAZIE 58 (5): 355-356 MAY 2003 Synthesis, crystal structure, stacking effect and antibacterial studies of a novel quaternary copper (II) complex with quinolone, MOLECULES 8 (2): 287-296 FEB 2003 Synthesis, crystal structure, antibacterial and antitumor activities of a new binuclear copper (II) complex containing fluoroquinolone, CHINESE JOURNAL OF INORGANIC CHEMISTRY 19 (2): 179-182 FEB 2003

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