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W. Xu*, K. Mou, Z. Lu, X. Kang, Y. Guo, B. Ding, Z. Chen, Z. Wang*, Q. Wu* Catalytic Promiscuity of Fatty Acid Photodecarboxylase Enables Stereoselective Synthesis of Chiral α-Tetralones Angew. Chem. Int. Ed. 2024, e202412862
J. Chen, S. Qi, Z. Wang, L. Hu, J. Liu, G. Huang, Y. Peng, Z. Fang, Q. Wu, Y. Hu*, K. Guo* Ene-Reductase-Catalyzed Aromatization of Simple Cyclohexanones to Phenols Angew. Chem. Int. Ed., 2024, e202408359
K. Mou, Y. Guo, W. Xu*, D. Li, Z. Wang*, Q. Wu* Stereodivergent Protein Engineering of Fatty Acid Photodecarboxylase for Light-Driven Kinetic Resolution of Sec-Alcohol Oxalates Angew. Chem. Int. Ed. 2024, e202318374
Y. Peng, K. Xia, Q. Wu* Photoinduced promiscuity of cyclohexanone monooxygenase for the enantioselective synthesis of α-deuterated carbonyl compounds Molecular Catal., 2024, 553, 113709
H. Zhou, P. Chuang, L. Xu, Q. Wu* Asymmetric Synthesis of Bulky N-Cyclopropylmethyl-1-aryl- 1-phenylmethylamines Catalyzed by Engineered Imine Reductases Org. Lett., 2023, 25, 6688–6692
J. Zhou, T. Han, S. Ahmad, D. Quinn, T. S. Moody, Q. Wu * and M. Huang* Origin of the enantioselectivity of alcohol dehydrogenase Phys. Chem. Chem. Phys., 2023, 25, 31292
C.Y. Cao, Q. Wu* Formaldehyde as a C1 source for chemo-enzymatic synthesis of high-value-added chemicals Chem Catal., 2023, 3, 100494.
Y.Z. Peng, Z. Wang, Y. Chen, W. Xu, Y. Hu, Z. Chen, J. Xu*, Q. Wu* Photoinduced Promiscuity of Cyclohexanone Monooxygenase for the Enantioselective Synthesis of α-Fluoroketones Angew. Chem. Int. Edit. 2022, 61, e202211199.
L. Wang, Y. Lou, W. Xu, Z. Chen, J. Xu*, Q. Wu* Biocatalytic Site-Selective Hydrogen Isotope Exchange of Unsaturated Fragments with D2O ACS Catal. 2022, 12, 783-788.
W. Xu, K. Mou, H. Zhou, J. Xu*, Q. Wu* Transformation of triolein to biogasoline by photo-chemo-biocatalysis Green Chem. 2022, 24, 6589-6598.
J. Zhang, Z. Zhang, Q. Wu,* J.L. Zhang* Synthesis of 1,2,3,4-Tetrahydroisoquinolines via Palladium-Catalyzed Cyclization of N-Tosylhydrazones with ortho-Bromophenethyl Tosylamides Adv. Synth. Catal. 2022, 364, 4075-4079.
J. Wang, Y.Z. Peng, J. Xu*, Q. Wu* Deracemization of racemic alcohols combining photooxidation and biocatalytic reduction Org. Biomol. Chem., 2022, 20, 7765–7769.
W. Xu, Y. Chen, D. Li, Z. Wang, J. Xu,* Q. Wu* Rational design of fatty acid photodecarboxylase enables the efficient decarboxylation of medium- and short-chain fatty acids for the production of gasoline bio-alkanes Molecular Catal., 2022, 524, 112261.
H. Hu, J. Huang, Y. Cao, Z. Zhang, F. He, X. Lin, Q. Wu*, S. Zhao*, Synthesis and Biological Evaluation of 1-(2-(6-Methoxynaphthalen-2-yl)-6-methylnicotinoyl)-4-Substituted Semicarbazides/Thiosemicarbazides as Anti-Tumor Nur77 Modulators Molecules 2022, 27, 1698.
Y. Peng, Z. Chen,* J. Xu, Q. Wu* Recent Advances in Photobiocatalysis for Selective Organic Synthesis Org. Process Res. Dev. 2022, 26, 7, 1900–1913.
J. Xu*,#, Y. Lou#, L. Wang#, Z. Wang#, W. Xu, W. Ma, Z. Chen, X. Chen,*, Q. Wu* Rational Design of Biocatalytic Deuteration Platform of Aldehydes ACS Catal. 2021, 11, 13348-13354.
D. Li, T. Han, J. Xue, W. Xu, J. Xu*, Q. Wu* Engineering Fatty Acid Photodecarboxylase To Enable the Highly Selective Decarboxylation of trans Fatty Acids Angew. Chem. Int. Edit. 2021, 60, 20695-20699.
J. Xu*,#, J. Fan#, Y. Lou#, W. Xu#, Z. Wang#, D. Li, H. Zhou, X. Lin & Q. Wu* Light-driven Decarboxylative Deuteration Enabled by a Divergently Engineered Photodecarboxylase Nature Comm. 2021, 12, 3983.
X.Y Chen*,#, Z. Wang#, Y. Lou, Y. Peng, Q. Zhu, J. Xu*, Q. Wu* Intramolecular Stereoselective Stetter Reaction Catalyzed by Benzaldehyde Lyase Angew. Chem. Int. Edit. 2021, 60, 9326-9329.
D. Li, X. Chen, Z. Chen, X. Lin, J. Xu*, Q. Wu*, Directed Evolution of Lipase A from Bacillus Subtilis for the Preparation of Enantiocomplementary Sec-alcohols Green. Synth. Catal. 2021, https://doi.org/10.1016/j.gresc.2021.07.003.
D.Y. Li, Y.J. Lou, J. Xu, X.Y. Chen,* X. Lin and Q. Wu*,Electronic Effect-guided Rational Design of Candida antarctica Lipase B for Kinetic Resolution Towards Diarylmethanols Adv. Synth. Catal. 2021, 363, 1867-1872.
Y. Zhang,# B. Xia,#,* Y. Li, X. Lin, Q. Wu*, Substrate Engineering in Lipase-catalyzed Selective Polymerization of D-/L-Aspartates and Diols to Prepare Helical Chiral Polyester Biomacromolecules, 2021, 22, 918-926. .
Y. Hu, W. Xu, C. Hui, J. Xu, M. Huang*, X. Lin, Q. Wu*, The Mutagenesis of a Single Site for Enhancing or Reversing the Enantio- or Regiopreference of Cyclohexanone Monooxygenases Chem. Comm., 2020, 56, 9356-9359.
J. Fan#, Y. Peng#, W. Xu, A. Wang, J. Xu*, H. Yu, X. Lin, Q. Wu*, Double Enzyme-Catalyzed One-Pot Synthesis of Enantiocomplementary Vicinal Fluoro Alcohols, Org. Lett., 2020, 22, 5446-5450.
Y. Peng, D. Li, J. Fan, W. Xu, J. Xu,* H. Yu, X. Lin, Q. Wu*, Enantiocomplementary C–H Bond Hydroxylation Combining Photo-Catalysis and Whole-Cell Biocatalysis in a One-Pot Cascade Process, Eur. J. Org. Chem. 2020, 821–825.
J. Xu#, Y. Peng#, Z. Wang, Y. Hu, J. Fan, H. Zheng, X. Lin, Q. Wu*, Exploiting Cofactor Versatility to Convert a FAD Dependent Baeyer Villiger Monooxygenase into a Ketoreductase, Angew. Chem. Int. Edit. 2019, 58, 14499-14503.
J. Xu, Y. Hu, J. Fan, M. Arkin, D. Li, Y. Peng, W. Xu, X. Lin & Q. Wu*, Light-Driven Kinetic Resolution of α-Functionalized Carboxylic Acids Enabled by Engineered Fatty Acid Photodecarboxylase, Angew. Chem. Int. Edit. 2019, 58, 8474-8478.
J. Xu, # Y.X. Cen,# W. Singh, J. Fan, L. Wu, X.F. Lin, J.H. Zhou*, M. Huang*, M. T. Reetz*, & Q. Wu*, Stereodivergent Protein Engineering of a Lipase to Access All Possible Stereoisomers of Chiral Esters with Two Stereo-centers J. Am. Chem. Soc. 2019, 141(19):7934-7945.
Y. Cen, W. Singh, M. Arkin, T.S. Moody, M. Huang,* J. Zhou,* Q. Wu,* M.T. Reetz,* Artificial Cysteine-Lipases with High Activity and Altered Catalytic Mechanism Created by Laboratory Evolution Nature Comm. 2019, 10(1), 3198.
Y.J. Hu, Y. Zhang, W.H. Xu, J. Xu, X.F. Lin, Q. Wu*, Dual-enzyme-Catalyzed Synthesis of Enantiocomplementary Polyesters, ACS Macro Lett, 2019, 8, 14321436.
Y. Zhang, B. Xia, Y.J. Hu, Q.Y. Zhu, X.F. Lin,* and Q. Wu*, Enantiocomplementary Chiral Polyhydroxyenoate: Chemoenzymatic Synthesis and Helical Structure Control, ACS Macro Lett, 2019, 8, 11881193.
B. Xia#, Y. Zhang#, Q. Zhu, X. Lin, Q. Wu*, Enzymatic synthesis and stereocomplex formation of chiral polyester containing long-chain aliphatic alcohol backbone, Biomacromolecules, 2019, 20, 35843591.
Y.J. Hu, J. Xu, Y. Cen, D. Li, Y. Zhang, M. Huang,* X. Lin, Q. Wu*, Customizing the Enantioselectivity of a Cyclohexanone Monooxygenase by a Strategy Combining “Size-probes” with in silico Study. Chemcatchem 2019,DOI: 10.1002/cctc.201901200.
Y. Zhang, Q. Zhu, Z. Fei, X. Lin, B. Xia,* Q. Wu*, Stereoselectivity-tailored chemo-enzymatic synthesis of enantiocomplementary poly (ω-substituted-δ-valerolactone) enabled by engineered lipase European Polymer Journal. 2019, 119, 52-60
Yixin Cen,# Danyang Li,# Jian Xu, Qiongsi Wu, Qi Wu,* and Xianfu Lin,* Highly Focused Library-Based Engineering of Candida antarctica Lipase B with (S)-Selectivity Towards sec-Alcohols Adv. Synth. Catal. 2019, 361, 126-134
Yujing Hu, Jie Wang, Yixin Cen, He Zheng, Meilan Huang*, Xianfu Lin and Qi Wu,* “Top’’ or ‘‘bottom’’ switches of a cyclohexanone monooxygenase controlling the enantioselectivity of the sandwiched substrate Chem. Commun., 2019, 55, 2198-2201
Jian Xu, Mamatjan•Arkin, Yongzhen Peng, Weihua Xu, Huilei Yu, Xianfu Lin and Qi Wu,* Enantiocomplementary Decarboxylative Hydroxylation Combining Photocatalysis and Whole-Cell Biocatalysis in One-pot Cascade Process Green Chemistry, 2019, 21, 1907–1911
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