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个人简介

1996年7月本科毕业于合肥工业大学。1999年7月获得中国科学技术大学高分子化学与物理硕士学位,导师为何平笙教授和阮德礼教授。2005年3月获Virginia Polytechnic Institute & State University有机与高分子化学博士学位,导师为Harry W. Gibson教授。后在University of Utah化学系从事博士后工作,导师为Peter J. Stang教授。2005年12月起任浙江大学化学系教授,筹建超分子化学研究小组。2008年3月起任浙江大学求是特聘教授。2018年5月起任浙江大学长江学者特聘教授。

研究领域

主要从事超分子化学方面的研究工作,当前的主要研究兴趣包括超分子聚合物、超分子两亲分子、柱芳烃超分子化学、以及非多孔自适应晶体(简称:纳客;英文全称:nonporous adaptive crystals;英文简称:NACs)、纳米碳。

近期论文

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Cao, J.; Zhu, H.;* Shangguan, L.; Liu, Y.; Liu, P.; Li, Q.; Wu, Y.; Huang, F.* A pillar[5]arene-based 3D polymer network for efficient iodine capture in aqueous solution. Polym. Chem. 2021, 12, 3517-3521. Chi, X.;* Tian, J.; Luo, D.; Gong, H.-Y.;* Huang, F.;* Sessler, J. L.* Texas-sized molecular boxes from chemistry to applications. Molecules 2021, 26, 2426. Khalil-Cruz, L. E.; Liu, P.; Huang, F.;* Khashab, N. M.* Multifunctional Pillar[n]arene-Based Smart Nanomaterials. ACS Appl. Mater. Interfaces 2021, 13, 31337-31354. Zhu, C. N.; Bai, T.; Wang, H.; Ling, J.; Huang, F.; Hong, W.; Zheng, Q.; Wu, Z. L.* Dual-Encryption in a Shape-Memory Hydrogel with Tunable Fluorescence and Reconfigurable Architecture. Adv. Mater. 2021, 33, 2102023. Gao, L.;* Wang, H.; Zheng, B.; Huang, F.* Combating antibiotic resistance: Current strategies for the discovery of novel antibacterial materials based on macrocycle supramolecular chemistry. Giant 2021, 7, 100066. Wu, Y.; Shangguan, L.; Li, Q.; Cao, J.; Liu, Y.; Wang, Z.; Zhu, H.;* Wang, F.* Huang, F.* Chemoresponsive Supramolecular Polypseudorotaxanes with Infinite Switching Capability. Angew. Chem. Int. Ed. 2021, 60, 19997-20002. Qiao, D.; Joshi, H.; Zhu, H.; Wang, F.; Xu, Y.; Gao, J.; Huang, F.; Aksimentiev, A.;* Feng, J.* Synthetic Macrocycle Nanopore for Potassium-Selective Transmembrane Transport. J. Am. Chem. Soc. 2021, 143, 15975-15983. Yang, J.;* Yu, G.;* Sessler, J. L.;* Shin, I.;* Gale, P. A.;* Huang, F.* Artificial transmembrane ion transporters as potential therapeutics. Chem 2021, 7, 3256–3291. Ding, Y.; Tong, Z.; Jin, L.; Ye, B.; Zhou, J.;* Sun, Z.; Yang, H.; Hong, L.; Huang, F.; Wang, W.;* Mao, Z.* A NIR Discrete Metallacycle Constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for Imaging-Guided Cancer Radiochemotherapy. Adv. Mater. 2022, 34, DOI: 10.1002/adma.202106388 Ju, H.; Zhu, C. N.; Wang, H.*; Page, Z. A.*; Wu, Z. L.*; Sessler, J. L.*; Huang, F.* Paper without a trail: Time-dependent encryption using pillar[5]arene-based host-guest invisible ink. Adv. Mater. 2022, 34, DOI: 10.1002/adma.202108163. Zeng, H.; Liu, P.; Xing, H.;* Huang, F.* Symmetrically Tetra-functionalized Pillar[6]arenes Prepared by Fragment Coupling. Angew. Chem. Int. Ed. 2022, 61, e202115823. Li, Q.; Wu, Y.; Cao, J.; Liu, Y.; Wang, Z.; Zhu, H.*; Zhang, H.*; Huang, F.* Pillararene-Induced Intramolecular Through-Space Charge Transfer and Single-Molecule White-Light Emission. Angew. Chem. Int. Ed. 2022, 61, e202202381. Fang, S.; Sun, W.; Lin, C.; Huang, F.; Li, H.* Self-Assembled Cage for In Situ Detecting Silver Cation in Water. Inorg. Chem. 2022, 61, 10.1021/acs.inorgchem.1c03825. Hua, B.; Shao, L.; Li, M.; Liang, H.; Huang, F.* Macrocycle-Based Solid-State Supramolecular Polymers. Acc. Chem. Res. 2022, 55, 1025-1034. Shi, T.; Huang, C.; Li, Y.; Huang, F.; Yin, S.* NIR-II phototherapy agents with aggregation-induced emission characteristics for tumor imaging and therapy. Biomaterials 2022, 285, 121535. Fang, S.; Wang, M.; Wu, Y.; Guo, Q.-H.; Li, E.;* Li, H.;* Huang, F.* Cagearenes: synthesis, characterization, and application for programmed vapor release. Chem. Sci. 2022, 13, 6254-6261. Zhu, H.; Li, Q.; Zhu, W.; Huang, F. Pillararenes as Versatile Building Blocks for Fluorescent Materials. Acc. Mater. Res. 2022, 3, 658-668. Cao, J.; Wu, Y.; Li, Q.; Zhu, W.; Wang, Z.; Liu, Y.; Jie, K.; Zhu, H.;* Huang, F.* Separation of pyrrolidine from tetrahydrofuran by using pillar[6]arene-based nonporous adaptive crystals. Chem. Sci. 2022, 13, 7536-7540. Lei, Y.; Li, Z.; Wu, G.; Zhang, L.; Tong, L.; Tong, T.; Chen, Q.; Wang, L.; Ge, C.; Wei, Y.; Pan, Y.; Sue, A. C.-H.;* Wang, L.;* Huang, F.;* Li, H.* A trefoil knot self-templated through imination in water. Nat. Commun. 2022, 13, 3557. Chen, L.; Sheng, X.; Li, G.;* Huang, F.* Mechanically interlocked polymers based on rotaxanes. Chem. Soc. Rev. 2022, DOI: 10.1039/D2CS00202G. Yang, X.; Wu, B.; Zhou, J.; Lu, H.; Zhang, H.; Huang, F.; Wang, H.* Controlling Intracellular Enzymatic Self-Assembly of Peptide by Host-Guest Complexation for Programming Cancer Cell Death. Nano Lett. 2022, 22, 7588-7596. Wang, Z.; Sheng, X.; Wu, Y.; Liu, Y.; Zhu, H.*; Huang, F.* Efficient Purification of 2,6-Lutidine by Nonporous Adaptive Crystals of Pillararenes. ACS Appl. Mater. Interfaces 2022, 14, 41072-41078. Li, E.; Zhu, W.; Fang, S.; Jie, K.*; Huang, F.* Reimplementing Guest Shape Sorting of Nonporous Adaptive Crystals via Substituent-Size-Dependent Solid-Vapor Postsynthetic Modification. Angew. Chem. Int. Ed. 2022, 61, e202211780. Liang, Y.; Li, E.; Wang, K.; Guan, Z.-J.; He, H.-h.; Zhang, L.; Zhou, H.-C.*; Huang, F.*; Fang, Y.* Organo-macrocycle-containing hierarchical metal-organic frameworks and cages: design, structures, and applications. Chem. Soc. Rev. 2022, 51, 8378-8405. Qi, S.; Zhang, H.; Zhang, X.; Yu, X.; Wang, Y.; Meng, Q.-F.; Yang, K.; Bai, B.; Tian, R.; Zhu, S.*; Rao, L.*; Huang, F.; Yu, G.* Supramolecular engineering of cell membrane vesicles for cancer immunotherapy. Sci. Bull. 2022, 67, 1898-1909. Wang, Z.-J.; Sheng, X.-R.; Li, G.-F.;* Yan, X.-Z.;* Huang, F.-H.* Woven Polymers. Acta Polym. Sin. 2022, 53, 1301-1315. Zhu, W.; Xing, H.; Li, E.; Zhu, H.;* Huang, F.* Room-Temperature Phosphorescence in the Amorphous State Enhanced by Copolymerization and Host-Guest Complexation. Macromolecules 2022, 55, 9802-9809. Wang, M.; Fang, S.; Yang, S.; Li, Q.; Khashab, N. M.; Zhou, J.*; Huang, F.* Separation of Ethyltoluene Isomers by Nonporous Adaptive Crystals of Perethylated and Perbromoethylated Pillararenes. Mater. Today Chem. 2022, 24, 100919. Liu, Y.; Li, M.; Ju, H.; Wang, Z.; Wu, Y.; Wu, Z. L.;* Zhu, H.;* Huang, F.* Dual Encryption of Digital Information in a Tough Fluorescent Hydrogel. Polym. Chem. 2022, 13, 6255-6260. Yang, K.; Hua, B.; Qi, S.; Bai, B.; Yu, C.;* Huang, F.; Yu, G.* Suprasomes Based on Host-Guest Molecular Recognition: An Excellent Alternative to Liposomes in Cancer Theranostics. Angew. Chem. Int. Ed. 2022, 61, e202213572. Yao, Y.; Liu, J.; Zhang, P.; Sun, K.; Jin, L.; Li, S.; Huang, F.; Ni, Z.;* Zhang, Z.* Solid-State Self-Assembly of Heteroditopic Copillar[5]arenes. Cryst. Growth Des. 2023, 23, 68-76. Zhang, Z.; Yao, Y.; He, L.; Hong, T.; Li, S.;* Huang, F.;* Stang, P. J.* Coordination-driven self-assembly of dibenzo-18-crown-6 functionalized Pt(II) metallacycles. Chin. Chem. Lett. 2023, 34, 107521 Li, M.; Liu, Y.; Shao, L.; Hua, B.;* Wang, M.; Liang, H.; Khashab, N. M.;* Sessler, J. L.;* Huang, F.* Pillararene-Based Variable Stoichiometry Co-Crystallization: A Versatile Approach to Diversified Solid-State Superstructures. J. Am. Chem. Soc. 2023, 145, 667-675. Peng, H.;* Zhu, W.; Guo, W.-J.; Li, Q.; Ma, S.; Bucher, C.; Liu, B.;* Ji, X.;* Huang, F.;* Sessler, J. L.* Supramolecular polymers: Recent advances based on the types of underlying interactions. Prog. Polym. Sci. 2023, 137, 101635. Liang, H.; Yang, Y.; Shao, L.; Zhu, W.; Liu, X.;* Hua, B.;* Huang, F.* Nanoencapsulation-Induced Second Harmonic Generation in Pillararene-Based Host–Guest Complex Cocrystals. J. Am. Chem. Soc. 2023, 145, 2870-2876. Ju, H.; Zhang, H.; Li, X. H.; Zuo, M.; Du, M.; Huang, F.; Zheng, Q.; Wu Z. L.* Polymerization-Induced Crystallization of Dopant Molecules: An Efficient Strategy for Room-Temperature Phosphorescence of Hydrogels. J. Am. Chem. Soc. 2023, 145, 3763-3773. Zhu, H.; Liu, J.; Wu, Y.; Wang, L.; Zhang, H.; Li, Q.; Wang, H.; Xing, H.;* Sessler, J. L.;* Huang, F.* Substrate-Responsive Pillar[5]arene-Based Organic Room-Temperature Phosphorescence. J. Am. Chem. Soc. 2023, 145, DOI: 10.1021/jacs.3c00711.

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