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个人简介

张全,男,博士,副教授,浙江省151第三层次人才。主要研究方向为环境毒理学和环境健康,着重以“污染物暴露-效应评价-生态与健康风险”为主线,围绕人们频繁暴露新型污染物(新型阻燃剂和新型烟碱类农药)的生态健康风险及机制开展一系列相关工作。已发表SCI论文40余篇,6篇发表在环境科学与工程国际顶级期刊EnvironmentalScience&Technology上,1篇研究论文曾入选环境与生态领域ESI高被引论文,另参编美国化学会(ACS)专著一部,授权国家发明专利2项。目前,已主持或参与国家自然科学基金等多项国家级项目2012年获浙江省自然科学学术奖三等奖。SCI引用400余次。浙江省新苗计划、浙江省挑战杯课外科技竞赛指导教师。 研究经历 2016/10-2017/10美国哈佛大学公共卫生学院VisitingScientist. 2012/06-2014/04浙江大学环境与资源学院博士后。 2010/04-2010/07美国休斯敦大学化学系Exchange 主持和参加的科研项目 国家自然科学基金面上项目,21777147、高效氯氰菊酯对幼鼠糖代谢 紊乱的对映体选择性及其机制研究、2018-2021、66万元、在研、主持 国家自然科学基金青年项目,21307109、环境浓度下拟除虫菊酯类农 药对斑马鱼多代慢性毒性研究、2014-2016、25万元、结题、主持; 中国博士后科学基金第六批特别资助,2013T60599、斑马鱼体内氟 虫腈生物转化对映体选择性机制研究、2013-2014、15万元、结题、主持; 中国博士后科学基金第52批面上资助,2012M521180、基于代谢组 学的氟虫腈斑马鱼发育毒性对映体差异研究、2012-2014、5万元、结题、主 持; 国家自然科学基金面上项目,21577129、线粒体损伤介导的亚致死剂 量烟碱类农药暴露蜜蜂隔代毒性机制研究、2016-2019、78.8万元、在研、参 与(2/8); 国家自然科学基金面上项目,21377119、斑马鱼体内拟除虫菊酯类农 药对映体选择性生物转化机制、2014-2017、85万元、在研、参与(2/9); 国家自然科学基金青年基金,21307110、非职业暴露浓度下二甲基甲 酰胺与肝损伤相关性及肝细胞凋亡机制研究、2014-2016、26万元、在研、参 与(3/8); 授权和受理专利 张全,赵美蓉,刘维屏,王萃。一种毛细管电泳拆分2,4,5滴丙酸对映体 的新方法。ZL200910154964.0。 赵美蓉,张全,刘维屏,王萃。一种毛细管电泳拆分2,4滴丙酸对映体的新 方法。ZL200910154742.9; 指导学生项目与获奖 2015年浙江省第十四届挑战杯课外学术科技竞赛二等奖:“潜在内分泌干扰 物的环境行为及其健康风险效应研究” 2016年浙江省“新苗计划”资助:手性农药甲霜灵对斑马鱼对的发育毒性及 生物转化机制研究 2014年浙江省新苗计划资助:典型有机磷阻燃剂的潜在内分泌干扰效应研 究

研究领域

研究方向 潜在环境内分泌干扰物的甄别及风险评价 新型烟碱类农药的整合暴露评估与人群健康风险

近期论文

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发表的主要论文(*为通讯作者) 1.LuCS,ChangCH,PalmerC,ZhaoMR,ZhangQ*.2018.NeonicotinoidsResiduesinFruitsandVegetables:AnIntegratedDietaryExposureAssessmentApproach.EnvironmentalScience&Technology.52,3175–3184. 2.ZhangQ,WangJH,ZhuJQ,LiuJ,ZhaoMR*.2017.Potentialglucocorticoidandmineralocorticoideffectsofnineorganophosphateflameretardants.EnvironmentalScience&Technology,51,5803-5810. 3.ZhangQ,LuMY,DongXW,HuYZ,WangC,ZhaoMR*.2014.Potentialestrogeniceffectsofphosphorus-containingflameretardants.EnvironmentalScience&Technology,48,69957001. 4.ZhangQ,WangJH,ZhuJQ,LiuJ,ZhangJY,ZhaoMR*.2016.Assessmentoftheendocrinedisruptingeffectsofshort-chainchlorinatedparaffinsininvitromodels.EnvironmentInternational,94,43-50. 5.ZhangQ,YJJ,ChenJY,XuHJ,WangC*,ZhaoMR*.2014.Riskassessmentofpolychlorinatedbiphenylsandheavymetalsinsoilsofanabandonede-wastesiteinChina.EnvironmentalPollution,185,258–265. 6.ZhangQ,LiZ,ChangCH,LouJL,ZhaoMR,LuCS*.2018.Potentialhumanexposurestoneonicotinoidinsecticides:Areview.Environmentalpollution,236,71-81. 7.ZhangQ,JiCY,YinXH,YanL,LuMY,ZhaoMR*.2016.Thyroidhormone-disruptingactivityandecologicalriskassessmentofphosphorus-containingflameretardantsbyinvitro,invivoandinsilicoapproaches.Environmentalpollution,210,27-33. 8.ZhangQ,JiCY,YanL,LuMY,LuCS,ZhaoMR*.2016.Theidentificationofthemetabolitesofchlorothalonilinzebrafish(Daniorerio)andtheirembryotoxicityandendocrineeffectsatenvironmentallyrelevantlevels.EnvironmentalPollution,218:8-15. 9.SongQ,ZhangY,YanL,WangJH,LuCS,ZhangQ*,ZhaoMR.2017.Riskassessmentoftheendocrine-disruptingeffectsofninechiralpesticides.JournalofHazardousMaterials,338:.57-65. 10.ZhangQ#,YanL#,WuY,JiL,ChenYC,ZhaoMR*,DongXW*.2017.Aternaryclassificationusingmachinelearningmethodsofdistinctestrogenreceptoractivitieswithinalargecollectionofenvironmentalchemicals.ScienceoftheTotalEnvironment,580:12681275. 11.ZhangQ,SongQ,WangC,ZhouC,LuCS,ZhaoMR*.2017.EffectsofglufosinateonthegrowthofandmicrocystinproductionbyMicrocystisaeruginosaatenvironmentallyrelevantconcentrations.ScienceoftheTotalEnvironment,575:513-518. 12.ZhangQ,ZhangY,DuJ,ZhaoMR*.2017.Environmentallyrelevantlevelsofλ-cyhalothrin,fenvalerate,andpermethrincausedevelopmentaltoxicityanddisruptendocrinesysteminzebrafish(Daniorerio)embryo.Chemosphere,185:1173-1180. 13.QianY,ZhouPX,ZhangQ*.2017.Developmentofenvironment-friendlyinsecticidesbasedonenantioselectivity:bifenthrinasacase.CurrentProteinPeptideScience,18(1):10-14. 14.ZhangQ*,ZhuJQ,YeJJ.ChenF,ZhaoMR.2016.TemporaltrendsandriskassessmentofpolychlorinatedbiphenylsandheavymetalsinasolidwastesiteinTaizhou,China.EnvironmentalSciencePollutionResearch,23(1):438-446. 15.ZhangQ,ZhouH,LiZ,ZhuJQ,ZhouC,ZhaoMR*.2016.EffectsofglyphosateatenvironmentallyrelevantconcentrationsonthegrowthofandmicrocystinproductionbyMicrocystisaeruginosa.EnvironmentalMonitoringandAssessment,188(11):632. 16.ChenH,ZhuJQ,LiZ,ChenA,ZhangQ*.2016.TheoccurrenceandriskassessmentoffiveorganophosphoruspesticidesinriverwaterfromShangyu,China.EnvironmentalMonitoringandAssessment,188(11):614. 17.ZhangQ,SongQ,LiJL,ZouML,ZhangCX,ZhangQ*.2016.Alterationoftheenantioselectivetoxicityofdiclofopacidbynonylphenol:effectonascorbate-glutathionecycleinMicrocystisaeruginosa.Chirality,28(6):475-481. 18.ZhangYJ,ZhangY,ChenA,ZhangW,ZhangQ*.2016.Enantioselectivityindevelopmentaltoxicityofrac-metalaxylandR-metalaxylinzebrafish(Daniorerio)Embryo.Chirality,28(6):489-494. 19.LuMY,DuJ,ZhouPX,ChenH,LuCS,ZhangQ*.2015.Endocrinedisruptingpotentialoffipronilanditsmetaboliteinreportergeneassays.Chemosphere,120:246-251. 20.ZhangQ,JiCY,YinXH,YanL,LuMY,ZhaoMR*.2014.Characterizationofestrogenreceptoralphaactivitiesinpolychlorinatedbiphenylsbyinvitrodual-luciferasereportergeneassay.Environmentalpollution,189,169-175.他引12次. 21.ZhangQ,LiuWP,GengSW,QuJP,LiuM,ZhangYM,ZhaoMR*.2014.Degradationofthepotentialrodentcontraceptivequinestrolandeliminationofitsestrogenicactivityinsoilandwater.EnvironmentalScienceandPollutionResearch,21,652-659. 22.WangC#,ZhangQ#,QianY,ZhaoMR*.2014.p,p’‑DDEinducesapoptosisthroughthemodulationoftumornecrosisfactorαinPC12cells.ChemicalResearchinToxicology,27,507-513. 23.ZhangQ,WangC*.2013.Toxicityofbinarymixturesofenantiomersinchiralorganophosphorusinsecticides:thesignificanceofjointeffectsbetweenenantiomers.Chirality,25,787-792. 24.ZhangQ,WangC,ZhangXF,JinDQ,HuangCJ*,ZhaoMR*.2012.Enantioselectiveaquatictoxicityofcurrentchiralpesticides.JournalofEnvironmentalMonitoring,14(2):465-472. 25.ZhangQ,WangC,LiuWP,ZhangXF,ZhuangSL*.2012.EvidenceforDNA-diquatinteractionandcytotoxicityininvitroratcells.EnvironmentalChemistryLetters,10,35-39. 26.ZhangQ,WangC,LiL,ZhaoMR*.2010.Cytotoxicityoflambda-cyhalothrinonthemacrophagecellLineRAW264.7.JournalofEnvironmentalSciences,22,428-432. 27.WangC#,ZhangQ#,ZhangXF,LiuJ,LiuWP*.2010.Understandingtheendocrinedisruptionofchiralpesticides:Theenantioselectivityinestrogenicactivityofsyntheticpyrethroids.ScienceChina,53,1003-1009. 28.HeXM,DongXW,ZouXW,YuDH,FangY,ZhangQY,ZhangQ,ZhaoMR.*2015.EnantioselectiveEffectsofo,p′DDTonCellInvasionandAdhesionofBreastCancerCells:ChiralityinCancerDevelopment. EnvironmentalScience&Technology,49(16):10028-10037. 29.ZhangY,LuMY,ZhouPX,WangC,ZhangQ,ZhaoMR*.2015.Multilevelevaluationsofpotentialliverinjuryofbifenthrin.PesticideBiochemistryandPhysiology,122,29-37. 30.ZhaoMR,ZhangY,ZhuangSL,ZhangQ,LiuWP*.2014.DisruptionoftheHormonalNetworkandtheEnantioselectivityofBifenthrininTrophoblast:Maternal-FetalHealthRiskofChiralPesticides.EnvironmentalScience&Technology,48,8109-8116. 31.WangC,LiZY,ZhangQ,ZhaoMR*,LiuWP*.2013.ChiralityinriskassessmentofPOPsmetabolite:enantioselectiveinductionofcytotoxicitybyo,p’-DDDinPC12cells.EnvironmentalScience&Technology,47,3909-3917. 32.ChenF,ZhangQ,WangC,LuYC,ZhaoMR*.2012.EnantioselectivityinestrogenicityoforganochlorineinsecticideacetofenateinhumantrophoblastandMCF-7.ReproductiveToxicology,33,53-59. 33.ZhangQ,ZhaoMR*,QianHF,LuT,ZhangQ,LiuWP*.2012.EnantioselectiveDamageofDiclofopAcidMediatedbyOxidativeStressandAcetyl-CoACarboxylaseinNontargetPlantArabidopsisthaliana.EnvironmentalScience&Technology,46,8405-8412. 34.ZhangQ,ZhouC,ZhangQ,QianHF,LiuWP*,ZhaoMR*.2012.StereoselectivePhytotoxicityofHCHMediatedbyPhotosyntheticandAntioxidantDefenseSystemsinArabidopsisthaliana.PLoSONE,8(1):e51043. 35.WangC,ZhangQ,ZhaoMR*,LiuWP.2011.ChiralPesticides:StereoselectivityanditsConsequences,In:EnantioselectivityinEstrogenicPotentialofChiralPesticides,AmericanChemicalSociety. 36.HuF,LiL,WangC,ZhangQ,XuC,ZhaoMR*.2010.EnantioselectiveinductionofoxidativestressbypermethrininratPC12cells.EnvironmentalToxicologicalChemistry,29,683-690. 37.ZhaoMR,ChenF,WangC,ZhangQ,GanJ,LiuWP*.2010.Integrativeassessmentofenantioselectivityinendocrinedisruptionandimmunotoxicityofsyntheticpyrethroids.EnvironmentalPollution,158,1968-1973. 38.TongCL*,YeRM,ZhangQ,LiuWP.2010.InteractionofS-MetolachlorwithcalfthymusDNA.ChemicalJournalofChineseUniversity,31,905-910. 39.WangC,ZhangN,LiL,ZhangQ,ZhaoMR*,LiuWP*.2010.EnantioselectiveInteractionwithAcetylcholinesteraseofanOrganophosphateInsecticideFenamiphos.Chirality,22,612617. 40.WangC,ChenF*,ZhangQ,FangZ.2009.ChronicToxicityandCytotoxicityoftheSyntheticPyrethroidInsecticidecis-bifenthrin.JournalofEnvironmentalSciences,21,1710-1715. 41.张全,王萃,赵美蓉,刘维屏*.2013.手性持久性有机污染物的环境界面过程及生态安全研究进展.中国科学,43,326-335.

学术兼职

Scholar.学术兼职 2014-美国毒理学会会员(SETAC) 2014-中国毒理学会会员 2009-浙江省生态学会会员 2012-生态和环境毒理学的国际主流期刊Environ.Sci.:Nano,Sci. ofTotalEnviron.,PestManga.Sci.,Environ.Toxicol.Chem.,Chemosphere, AquaticToxicol.等学术审稿人。

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