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药物合成和有机合成反应 有机小分子催化构筑新型具有药物活性的功能性分子方面是近年来新兴的比较活跃的一个研究方向,该方向可以避免传统的金属催化对于环境的影响从而有望在工业上进行大剂量的合成。有机卡宾催化构筑C-C键的反应便是其中最为活跃的分支之一,本课题多年来从事于利用有机卡宾催化合成杂环类药物分子,具体研究方向主要包括:  氮杂卡宾(NHC)分子的设计以及合成  类似的其他杂环卡宾的合成 新型卡宾在C-C键构筑方面的反应研究 具有药物活性的天然产物的全合成 具有药物活性的有机分子的设计以及合成 有机化学反应的工艺优化

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NaIO4-Catalyzed One-Pot Synthesis of Dihydropyrimidinones at Room Temperature under Solvent-Free Conditions,Jing, X. B.; Li, Z.; Pan, X.; Shi, Y. C.; Yan, C. G. Journal of Iranian Chem. Soc. 2009, 6, 514-518. Organic Catalytic Multicomponent One-Pot Synthesis of Highly Substituted Pyrroles,Jing, X. B.; Pan, X.; Li, Z.; Bi, X. X.; Yan, C. G.; Zhu, H. X., Syn. Commun. 2009, 39, 3833-3844. PdO-Catalyzed Synthesis of Tricyclic Compounds Using Biginelli-Like Reaction,Jing, X. B.; Li, Z.; Pan, X.; Wang, Q.; Yan, C. G.; Zhu, H. X. Syn. Commun., 2009, 39, 3796-3803 Novel One-Pot Procedure for the Synthesis of 1,2-Diketones,Jing, X. B.; Pan, X.; Li, Z.; Shi, Y. C.; Yan, C. G. Syn. Comm,2009, 39, 492-496 微波辐射下苯并咪唑化合物的合成方法,专利批准号:ZL200610039854.6 合成香兰素得到的固体废物的循环处理方法专利批准号:ZL200610039853.1 1,3,5-三苯基苯的新合成方法专利批准号:ZL200610039855.0 A Novel Method for the Synthesis of 4(3H)-Quinazolinones,景崤壁* 李 振,潘 鑫,石尧成Journal of the Chinese Chemical Society, 2008, 55, 1145-1149 Recent progress in Ferrocene-based Dendrimer,Xiaobi Jing, Feng Xu, Wei Xu, Changuo Yan,Chinese Journal of Organic Chemistry,27(4),2007,457-470 Rapid One‐Pot Preparation of 2‐Substituted Benzimidazoles from Esters using Microwave Conditions,Jing, Xiaobi; Zhu, Qihua; Xu, Feng; Ren, Rinfeng; Li, Dong; Yan, Chaoguo, Synthetic communications, Volume 36, Number 18, 2006, pp. 2597-2601(5) Novel method for the synthesis of 1,3,5-triarylbenzenes from ketones Xiaobi Jing, Feng, Xu, Qihua Zhu, Xinfeng, Ren, Chaoguo Yan, Li Wang, Jingrong Wang, Synthetic communications, 2005, vol. 35, no24, pp. 3167-3171 One Step of Palladium Catalyzed Benzodioxane Ring C-O Bond Formation, Synthesis of Isoamericanol A and Isoamericanin A , Xiaobi Jing; Yaocheng Shi ; Yonghong Liu; Ying Han; Chaoguo Yan; Li Wang, Synthetic Communications, Volume 34, Issue 9 December 2004 , pages 1723 - 1727 New method for the synthesis of 1,3,5-triarylbenzenes, Xiaobi Jing, Feng Xu, Qihua Zhu, Xinfeng Ren, Indian Journal of chemistry, 2006, 45B, 2781-2783. Total synthesis of six benzodioxane Neoliganas, Xiaobi Jing, Li Wang et. al. Journal of Chinese Chemical Society, 2004, Facile synthesis of Isoamericcanol and Isoamericanin A, Xiaobi Jing, Chaoguo Yan, et. al. Chinese Chemical Letters, 2004

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