个人简介

王华峰，男，医学博士，讲师。现承担《遗传学》、《免疫学》等课程的教学

研究领域

主要研究方向是基础医学，涉及免疫炎症、肝损伤修复机制、肿瘤等方面

主持或参加科研、教改项目 2018年山西省高等学校教学改革创新项目（山西省教育厅），J2018250，高中生物新课标中“表观遗传”模块的理解与传授，2018/05-2020/05，2万元（在研），主持 山西师范大学现代文理学院自然基金，2016KJYJ-6，某公司生产的蛋氨酸-胆碱缺乏饲料诱导的非酒精性脂肪性肝炎小鼠模型的构建与评价，2016/01-2017/12，1万元（结题），主持 国家自然科学基金委青年科学基金项目，31600730，C10orf90调节巨噬细胞极化和黑色素瘤免疫逃逸的作用机制研究，2017/01-2019/12，20万元（在研），参加 国家自然科学基金委面上项目，81272317、S100P调节胰腺癌免疫逃逸的作用机制研究、2013,01-2016,12、70万元（结题），参加 科技部-国家重大科学研究计划（973重大）“肝癌治疗的新型纳米药物研究”项目子课题，2012CB932503、新型纳米药物调控肝癌免疫微环境的机制和药效学研究（已结题）、参加

近期论文

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WangHuafeng,ZhangHuan,HuangBiao,MiaoGuolin,YanXiaoyan,GaoGang,LuoYongping,ChenHuize,ChenWei,YangLuhong.MesenchymalstemcellsreversehighfatdietinducednonalcoholicfattyliverdiseasethroughsuppressionofCD4+Tlymphocytesinmice[J].Molecularmedicinereports,2018,17(3):3769-3774. ChengXixi,WangHuafeng,YangJinlai,ChengYingnan,WangDan,YangFengrui,LiYan,ZhouDongmei,WangYanxia,XueZhenyi,ZhangLijuan,ZhangQi,YangLuhong,ZhangRongxin,DaYurong.Arctigeninprotectsagainstliverinjuryfromacutehepatitisbysuppressingimmunecellsinmice[J].Biomedicine&pharmacotherapy=Biomedecine&pharmacotherapie,2018,102:464-471.（共一） HuafengWang,LuhongYang,WangDong,ZhangQi,LijuanZhang.Pro-tumoractivitiesofmacrophagesintheprogressionofmelanoma[J].HumanVaccines&Immunotherapeutics,2017,13(7):1556-1562. HuafengWang,LijuanZhang,LuhongYang,ChengfangLiu,QiZhang,LinjingZhang.Targetingmacrophageanti-tumoractivitytosuppressmelanomaprogression[J].Oncotarget,2017,8(11):18486-18496. WangHuafeng,WangDong,YangLuhong,WangYanxia,JiaJunli,NaDongchen,ChenHuize,LuoYongping,LiuChengfang.Compactbone-derivedmesenchymalstemcellsattenuatenonalcoholicsteatohepatitisinamousemodelbymodulationofCD4cellsdifferentiation[J].IntImmunopharmacol,2017,42:67-73. WangHuafeng,ZhangHuan,ZhangYuqing,WangDan,ChengXixi,YangFengrui,ZhangQi,XueZhenyi,LiYan,ZhangLijuan,YangLuhong,MiaoGuolin,LiDaiqing,GuanZhiyu,DaYurong,YaoZhi,GaoFei,QiaoLiang,KongLi,ZhangRongxin.Plumbaginprotectsliveragainstfulminanthepaticfailureandchronicliverfibrosisviainhibitinginflammationandcollagenproduction[J].Oncotarget,2016 HuafengWang,HuanZhang,ZimuZhang,BiaoHuang,XixiCheng,DanWang,ZhalaGahu,ZhenyiXue,YurongDa,DaiqingLi,ZhiYao,FeiGao,AiminXu,andRongxinZhang,Adiponectin-derivedactivepeptideADP355exertsanti-inflammatoryandanti-fibroticactivitiesinthioacetamide-inducedliverinjury[J].Scientificreports,2016,6(19445) WangDan,WangHuafeng,FuShuyu,ChengXixi,YangFengrui,ZhangQi,LiYan,XueZhenyi,ZhangLijuan,HuangWenjing,YangLuhong,NaDongchen,DaYurong,KongYing,ZhangRongxin.ParthenolideamelioratesConcanavalinA-inducedacutehepatitisinmiceandmodulatesthemacrophagestoananti-inflammatorystate[J].InternationalImmunopharmacology,2016,(38):132-138.（共一） BiaoHuang,XixiCheng,HuafengWang,WenjingHuang,ZhalaGahu,DanWang,KaiZhang,HuanZhang,ZhenyiXue,YurongDa,NingZhang,YongchengHu,ZhiYao,LiangQiao,FeiGao,RongxinZhang,Mesenchymalstemcellsandtheirsecretedmoleculespredominantlyamelioratefulminanthepaticfailureandchronicliverfibrosisinmicerespectively[J].Journaloftranslationalmedicine,2016,14(1):45（共一） ZhenyiXue,WenLi,HuafengWang,BiaoHuang,ZhenzhenGe,ChaoGu,YingLiu,KaiZhang,JuhongYang,RongHan,MeiyuPeng,YanLi,DaZhang,YurongDa,ZhiYao,RongxinZhang,ZSTK474,anovelPI3Kinhibitor,modulateshumanCD14+monocyte-deriveddendriticcellfunctionsandsuppressesexperimentalautoimmuneencephalomyelitis[J].JournalofMolecularMedicine,2014,92(10):1057-1068（共一） JiaLong,QingXi,HuafengWang,ZimuZhang,HongkunLiu,YingnanCheng,XiangdongGuo,JieyouZhang,ZhangQi,LijuanZhang.miR-142-5pregulatestumorcellPD-L1expressionandenhancesanti-tumorimmunity[J].Biochemical&BiophysicalResearchCommunications,2017,488(2):425-431. KaiZhang,ZhenzhenGe,ZhenyiXue,WenjingHuang,MeiMei,QiZhang,YanLi,WenLi,ZhihuiZhang,ZimuZhang,LijuanZhang,HuafengWang,JinzhenCai,ZhiYao,RongxinZhang,YurongDa,ChrysinsuppresseshumanCD14+monocyte-deriveddendriticcellsandamelioratesexperimentalautoimmuneencephalomyelitis,JournalofNeuroimmunology,2015,288:13-20 KaiZhang,ZhenzhenGe,YurongDa,DongWang,YingLiu,ZhenyiXue,YanLi,WenLi,LijuanZhang,HuafengWang,HuanZhanga,MeiyuPenga,b,c,d,JunweiHao,ZhiYao,RongxinZhang,Plumbaginsuppressesdendriticcellfunctionsandalleviatesexperimentalautoimmuneencephalomyelitis[J].JournalofNeuroimmunology,2014,273(1-2):42-52 XiWu,MeiyuPeng,BingqingHuang,HuanZhang,HuafengWang,BiaoHuang,ZhenyiXue,LijuanZhang,YurongDa,DeYang,ZhiYao,RongxinZhang.Immunemicroenvironmentprofilesoftumorimmuneequilibriumandimmuneescapestatesofmousesarcoma.CancerLetters.2013,340:124–133 王华峰,任铎锋,刘玲.蜂王的分化发育与表观遗传[J].生物学通报,2018,53(11):6-8. 王华峰,刘玲,孙瑞娴,段江燕.切除了胸腺,还有体液免疫吗——从抗原出发[J].中学生物教学,2018(Z1):93-95. 王华峰,刘玲,孙瑞娴,芦荣胜.性格形成中的表观遗传机制[J].生物学教学,2017(11). 王华峰,刘玲,卢荣胜.罗宾·霍利迪:表观遗传机制——DNA甲基化学说的提出者[J].中学生物教学,2017(10):45-46. 王华峰,孙瑞娴.表观遗传学的提出者——沃丁顿[J].中学生物教学,2017(06):50-51. 刘玲,孙瑞娴,徐应春,史江宁,王华峰.酵母细胞固定化实验的教学改进及建议[J].生物学通报,2016,51(12):42-43.（通讯作者），被人大书报资料中心复印报刊资料全文转载于2017年04期的《中学政治及其他学科的教与学》。