谭黎峰 - 湘潭大学

研究领域

（1）核酸DNA/RNA的结构识别及其生物功能的化学调控（2）核酸/酶为靶分子的抗肿瘤药物设计合成及应用化学生物学

近期论文

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Jing Liu, Lingjun Xie, Xiaonan Sun, Lifeng Tan*, Binding properties of Ru(II) polypyridyl complexes with poly(U)•poly(A)*poly(U) triplex: the ancillary ligand effect on third-strand stabilization, Journal of Biological Inorganic Chemistry, 2013, 18, 71–80. (影响因子：3.289.） Lifeng Tan*, Lingjun Xie, Xiaonan Sun, Leli Zeng, Guang Yang, Biophysical insights into the interaction of Ru(II) polypyridyl complexes with the RNA triplex poly(U)·poly(A)*poly(U). Intercalative ligand shape effect on third-strand stabilization, Journal of Inorganic Biochemistry, 2013, 120, 32–38. (影响因子：3.354.） Lifeng Tan*,Jin Liu, Jianliang Shen, Xiaohua Liu, Leli Zeng, Lianhe Jin，First ruthenium(II) polypyridyl complex as a true molecular “light switch” for triplex RNA Structure: [Ru(phen)2(mdpz)]2+ enhances the Stability of poly(U)·poly(A)*poly(U)，Inorganic Chemistry, 2012, 51, 4417−4419. (影响因子：4.601.） Lifeng Tan*, Jianliang Shen, Jing Liu, Leli Zeng, Lianhe Jin, Chao Weng, Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru(II) mixed-ligand complexes，Dalton Transactions, 2012, 41, 4575–4587. (影响因子：3.838.） Xiling Liang, Xiaoqing Zou, Lifeng Tan*, Weiguo Zhu, Study on nucleic acid (CT-DNAand yeast tRNA) binding behaviors and cytotoxic properties of a heterodinuclear Ru(II)–Co(III) polypyridyl complex，Journal of Inorganic Biochemistry, 2010, 104: 1259-1266. (影响因子：3.354.） Lifeng Tan*, Xiling Liang, Xiaohua Liu, Synthesis, Double stranded DNA-binding and photocleavage studies of a functionalized ruthenium(II) complex with 7,7'-methylene-dioxy-phenyldipyrido[3,2-a:2',3'-c]-phenazine. Journal of Inorganic Biochemistry, 2009, 103(2): 441-477. (影响因子：3.354.） Lifeng Tan*, Fang Wang, Hui Chao, Chao Weng, Fanyang Zhou, Ruthenium(II) mixed-ligand complex containing 2-(4′-benzyloxy-phenyl)imidazo[4,5-f][1,10]-Phenanthroline: Synthesis, DNA-binding and photocleavage studies. Journal of Inorganic Biochemistry, 2007, 101(4): 700-708. (影响因子：3.354）ScienceDirect Top25 Hottest Papers in Journal of Inorganic Biochemistry (April - June 2007) Lifeng Tan*, Xiaohua Liu, Hui Chao, Liangnian Ji, Synthesis, DNA-binding and photocleavage studies of ruthenium(II) complex with 2-(3′-phenoxyphenyl)Imidazo-[4,5-f][1,10]-phenanthroline. Journal of Inorganic Biochemistry, 2007, 101(1): 56-63. (影响因子：3.354.） Lifeng Tan*, Hui Chao, DNA-binding and photocleavage studies of mixed polypyridyl ruthenium(II) complexes with calf thymus DNA, Inorganic a Chimica Acta, 2007, 360(6): 2016-2022. ScienceDirect Top25 Hottest Papers in Inorganica Chimica Acta (April - June 2007)