研究领域
1) 核酸识别小分子的设计合成及其相互作用研究；
2) 化学探针、电化学生物传感器研究；
3) 生物活性分子的设计合成及活性研究。
近期论文
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Hanping He, Jingping Xia, Gang Chang, Xiaoqian Peng, Zhaowen Lou, Kazuhiko Nakatani, Xiang Zhou, Shengfu Wang, Selective recognition of G-G mismatch using the Double Functional Probe with electrochemical active ferrocenyl, Biosensors and Bioelectronics, 2013, 42, 36-40.
Masaki Hagihara, Hanping He, Maki Kimura, Kazuhiko Nakatani, A small molecule regulates hairpin structures in d(CGG)trinucleitide repeats, Bioorganic & Med. Chem.Lett. 2012, 22, 2000-2003.
Hanping He, Masaki Hagihara, Kazuhiko Nakatani. Small molecule affecting replication of trinucleotide repeat d(GAA)n, Chem. Eur. J, 2009, 15, 10641-10648. (Impact Factor: 5.454).
Tao Peng, Hanping He, and Kazuhiko Nakatani. Monitoring PCR Progress with the Primer Labeled by Trinucleotide Repeat Sequence. ChemBioChem. 2008, 9, 1893-1897.
Kazuhiko Nakatani, Hanping He, Shin-nosuke Uno, Tsuyoshi Yamamoto, and Chikara Dohno. Synthesis of Dimeric2-Amino-1, 8-Naphthyridine and Related DNA-Binding Molecules. Current Protocols in Nucleotide Acid Chemistry 2008, UNIT 8.6, 1-21.
Hanping He, Yan Zhou, Dongqing Li, Feng Liang, Juanjuan Wu, Li Yang, Xiang Zhou, Xiaolian Zhang, Xiaoping Cao. Combination of Porphyrins and DNA-alkylation Agents: Synthesis and Tumor Cell Apoptosis Induction. Bioorganic & Med. Chem. 2006, 14 (4), 1068-1077.
Hanping He, Tian Tian, Ping Wang, Lin Wu, Jingjing Xu, Xiang Zhou, Xiaolian Zhang, Xiaoping Cao and Xiaojun Wu. Porphyrin-DNA cross-link agent hybrids: chemical synthesis and biologic studies. Bioorganic & Medicinal Chemistry Letter 2004, 14 (12), 3013~3016.
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