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致病菌的快速、灵敏、特异性检测技术化学生物学与功能蛋白质组学研究建立高效的短肽与蛋白展示库筛选平台蛋白-蛋白相互作用研究

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Yang LL, Zhou YX, Zhu SB, Huang TX, Wu LN, Yan XM*, Detection and Quantification of Bacterial Autofluorescence at the Single-Cell Level by a Laboratory-Built High-Sensitivity Flow Cytometer, Anal. Chem. 2012, 84, 1526–1532. Wu LN,Huang TT,Yang LL,Pan JB,Zhu SB,Yan XM*. Sensitive and selective bacterial detection using tetracysteine-tagged phages in conjunction with biarsenical dye. Angew. Chem. Int. Ed. 2011,50,5873 - 5877. Yang LL, Wu LN, Zhu SB, Long Y, Hang W, Yan XM*, Rapid, absolute, and simultaneous quantification of specific pathogenic strain and total bacterial cells using an ultrasensitive dual-color flow Cytometer, Anal. Chem. 2010, 82, 1109-1116. Wu LN, Lin XM, Peng XX*, From Proteome to Genome for Functional Characterization of pH-Dependent Outer Membrane Proteins in Escherichia coli, J. Proteome Res. 2009, 8, 1059-1070. Yang LL, Zhu SB, Hang W, Wu LN, Yan XM*, Development of an ultrasensitive dual-channel flow cytometer for the individual analysis of nanosized particles and biomolecules, Anal. Chem. 2009, 81, 2555-2563. Lin XM, Wu LN, Li H, Wang SY, Peng XX*, Downregulation of Tsx and OmpW and upregulation of OmpX are required for iron homeostasis in Escherichia coli, J. Proteome Res. 2008, 7, 1235-1243. Wu LN, Lin XM, Wang FP, Ye DZ, Xiao X, Wang SY, Peng XX*, OmpW and OmpV Are Required for NaCl Regulation in Photobacterium damsela, J. Proteome Res. 2006, 5, 2250-2257. Huang CZ, Lin XM, Wu LN, Zhang DF, Liu D, Wang SY, Peng XX*, Systematic identification of the sub-proteome of Escherichia coli cell envelope reveals the interaction network of membrane proteins and membrane-associated peripheral proteins, J. Proteome Res. 2006, 5, 3268-3276. Peng XX*, Xu CX, Ren HX, Lin XM, Wu LN, Wang SY, Proteomic analysis of the Sarcosine-insoluble outer membrane fraction of Pseudomonas aeruginosa responding to ampicilin, kanamycin, and tetracycline resistance, J. Proteome Res. 2005, 4, 2257-2265. Xu CX, Wang SY,Ren HX, Lin XM, Wu LN, Peng XX*, Proteomic analysis on the expression of outer membrane proteins of Vibrio alginolyticus at different sodium concentrations, Proteomics 2005, 5, 3142-3152.

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