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个人简介

2000-Present Professor Department of Chemical Biology, Xiamen University, Xiamen 2007-Present Director Committee of Origin of life and Evolution, Chinese Society of Space Research, Xiamen University, Xiamen, China 1988-Present Professor Department of Chemistry, Tsinghua University, Beijing 1993-2004 Director The Key Laboratory for Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 1979-1988 Associate Professor; Professor Institute of Chemistry, Academia Sinica, Beijing, China 1975-1979 Postdoctoral Associate State University of New York at Stony Brook and New York University, NIH Fellowship (Prof, Robert Shapiro) 1971-1975 Ph.D. State University of New York at Stony Brook, Supervisor: Prof. Fausto Ramirez 1971 B.S. National Tsinghua University in Taiwan

研究领域

生命有机化学,有机磷化学,生命起源,药物化学,化学生物学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

A Theoretical Study on the Mechanism of Ruthenium(II)-Catalyzed Phosphoryl-Directed ortho-Selective C-H Bond Activations: the Phosphoryl Hydroxy Group Triggered Ru(II)/Ru(0) Catalytic Cycle. Chen, P.; Sun, Y.; Wu, Y.; Liu, L.; Zhu, J.; Zhao, Y., Org. Chem. Front. 2017, 4, 1482-1492. (Highlighted by outside front cover) Catalytic Hydroboration of Aldehydes, Ketones, Alkynes and Alkenes Initiated by NaOH. Wu, Y.; Shan, C.; Ying, J.; Su, J.; Zhu, J.; Liu, L. L.; Zhao, Y., Green Chem., 2017, DOI: 10.1039/C7GC01632H Phosphinodifluoroalkylation of Alkynes Using P(O)H Compounds and Ethyl Difluoroiodoacetate. Zhang, P.; Ying, J.; Tang, G.; Zhao, Y., Org. Chem. Front. 2017. DOI: 10.1039/C7QO00466D An Easy Fabrication of Glucose Oxidase-Dipeptide-Reduced Graphene Oxide Nanocomposite for Glucose Sensing. Wu, Y.; Kong, Y.; Lu, K.; Lv, M.; Ye, Y.; Zhao, Y., Mater. Res. Bull. 2017, 94, 378-384. Toward a Stable Electrochemical Interphase with Enhanced Safety on High-Voltage LiCoO2 Cathode: A Case of Phosphazene Additives. Ji, Y.; Zhang, P.; Lin, M.; Zhao, W.; Zhang, Z.; Zhao, Y.; Yang, Y., J. Power Sources 2017, 359, 391-399. Recent progress toward organophosphorus compounds based on phosphorus-centered radical difunctionalizations. Gao, Y.; Tang, G.; Zhao, Y., Phosphorus, Sulfur Silicon Relat. Elem. 2017, 192, 589-596. (Invited contribution for Harry Hudson Special Issue) Stable isotope N-phosphoryl amino acids labeling for quantitative profiling of amine-containing metabolites using liquid chromatography mass spectrometry. Zhang, S.; Shi, J.; Shan, C.; Huang, C.; Wu, Y.; Ding, R.; Xue, Y.; Liu, W.; Zhou, Q.; Zhao, Y.; Xu, P.; Gao, X., Anal. Chim. Acta 2017, 978, 24-34. Direct Synthesis of 2-Sulfonated 9H-Pyrrolo[1,2-a]indoles via NaI-Catalyzed Cascade Radical Addition/Cyclization/Isomerization. Zhang, P.; Gao, Y.; Chen, S.; Tang, G.; Zhao, Y., Org. Chem. Front. 2017, 4, 1350-1353. Visible Light as a Sole Requirement for Intramolecular C(sp3)-H Imination. Li, J.; Zhang, P.; Jiang, M.; Yang, H.; Zhao, Y.; Fu, H., Org. Lett. 2017, 19, 1994-1997. One-Pot Synthesis of Aryl Pyrazole C-Nucleoside Analogs of Pyrazofurin from Sugar Alkynes. Liu, H.; Liang, Y.; Jia, T.-T.; Han, F.; Zhang, F.; Zhao, Y., Eur. J. Org. Chem. 2017, 2017, 1443-1449. Acetonitrile-Dependent Oxyphosphorylation: A Mild One-Pot Synthesis of β-Ketophosphonates from Alkenyl Acids or Alkenes. Chen, X.; Chen, X.; Li, X.; Qu, C.; Qu, L.; Bi, W.; Sun, K.; Zhao, Y., Tetrahedron 2017, 73, 2439-2446. MALDI MS-based analysis of oligosaccharides using 4-(diphenylphosphinyl) benzenamine as non-reductive amination derivatization reagent. Yang, X.; Gan, J.; Yuan, H.; Chen, P.; Liu, Y.; Jiang, Y.; Liu, H.; Zhao, Y., Int. J. Mass Spectrom. 2017, 417, 76-82. A concise synthesis of novel aryl pyrimidine C-nucleoside analogs from sugar alkynes. Zhang, F.; Liang, Y.; Li, J.; Gao, F.; Liu, H.; Zhao, Y., Asian J. Org. Chem. 2017, 6, 561-565. Iodine-mediated sulfonylation of quinoline N-oxides: a mild and metal-free one-pot synthesis of 2-sulfonyl quinolines. Fu, W.-K.; Sun, K.; Qu, C.; Chen, X.-L.; Qu, L.-B.; Bi, W.-Z.; Zhao, Y.-F., Asian J. Org. Chem. 2017,6, 492-495. Prophylactic vaccine based on pyroglutamate-3 amyloid β generates strong antibody response and rescues cognitive decline in alzheimer’s disease model mice. Li, G.; Hu, Z.-W.; Chen, P.-G.; Sun, Z.-Y.; Chen, Y.-X.; Zhao, Y.-F.; Li, Y.-M., ACS Chem. Neurosci. 2017, 8, 454-459. Self-assembled dipeptide-graphene nanostructures onto an electrode surface for highly sensitive amperometric hydrogen peroxide biosensors. Wu, Y.; Wang, F.; Lu, K.; Lv, M.; Zhao, Y., Sens. Actuators B Chem. 2017, 244, 1022-1030. Copper-Catalyzed Cascade Radical Addition-Cyclization Halogen Atom Transfer between Alkynes and Unsaturated α-Halogenocarbonyls. Gao, Y.; Zhang, P.; Ji, Z.; Tang, G.; Zhao, Y., ACS Catal. 2017, 7, 186-190. Synthesis of novel phosphorylated chrysin derivatives by 1,3-dipolar cycloaddition reaction. Zhu, S.; Zhang, Y.; Li, P.; Bi, W.; Chen, X.; Zhao, Y., Phosphorus, Sulfur Silicon Relat. Elem. 2017, 192, 1-8. Mn(OAc)3-Mediated Synthesis of 3-Phosphonyldihydrofurans from β-Ketophosphonates and Alkenes. Lu, G.; Lin, B.; Gao, Y.; Ying, J.; Tang, G.; Zhao, Y., Synlett, 2017, 28, 724-728.

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