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研究领域

主要从事有机合成方法学、不对称合成方法学的开发及应用研究;重要有机化合物分子的手性合成研究。

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Catalytic Asymmetric Direct a-Alkylation of Amino Esters by Aldehydes via Imine Activation. Xu, B.; Shi, L.-L.; Zhang, Y.-Z.; Wu, Z.-J.; Fu, L.-N.; Luo, C.-Q.; Zhang, L.-X.; Peng, Y.-G.; Guo, Q.-X.*, Chem. Sci., (IF2013 = 8.601), 2014, 5, 1988. Highly Efficient [3+2] Reaction of 3-Vinylindoles with 3-Indolylmethanols by Brønsted-Acid Catalysis. Zhang, C.; Zhang, L.-X.; Qiu, Y.; Xu, B.; Zong, Y.; Guo, Q.-X.*, RSC Adv.,(IF2012 = 3.709), 2014, 4, 6916. Diastereoselective Synthesis of Ring-Fused Thiocarbamates Bearing Contiguous Quaternary Carbon Centers. Guo, Q.-X*.; Zhang, L.-J.; Song, L.; Xu, B.; Xiao, D.-R.; Peng, Y.-G*., Tetrahedron Letters, (IF2012 = 2.376), 2013, 54, 3565. Organocatalytic Aldol Reaction of Indole-3-carbaldehydes with Ketones: Synthesis of Chiral 3-Substituted Indoles. Guo, Q.-X.*; Wen, W.; Fu, L.-N.; Zhang, S.-E.; Zhang, L.-X.; Liu, Y.-W.; Xu, B.; Xiong, Y., Tetrahedron Letters, (IF2012 = 2.376), 2013, 54, 4653. Multistep One-pot Synthesis of Enantioenriched Polysubstituted Cyclopenta[b]indoles, Xu, B., Guo, Z.-L., Jin, W.-Y., Wang, Z.-P., Peng, Y.-G., Guo, Q.-X*., Angew. Chem. Int. Ed. (IF2012 = 13.730), 2012, 51, 1059. The Direct Asymmetric a-Alkylation of Ketones by Brønsted-Acid Catalysis, Song, L., Guo, Q.-X*., Li, X.-C., Tian, J., Peng, Y.-G*., Angew. Chem. Int. Ed. (IF2012 = 13.730), 2012, 51, 1899. The Direct a-Alkylation of Aldehydes by Brønsted-Acid Catalysis. Zhu, X.-R.; Wang, T.; Guo, Q.-X*. Chinese Journal of Chemistry (IF2012 = 0.790), 2012, 30, 15. Enantioselective and Solvent-Controlled Diastereoselective Mannich Reaction of Isatin imines with Hydroxyacetone: Synthesis of 3-Substituted 3-Aminooxindoles. Guo, Q.-X*.; Liu, Y.-W.; Li, X.-C.; Zhong, L.-Z.; Peng, Y.-G. J. Org. Chem. (IF2012 = 4.450), 2012, 77, 3589. Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis, Guo, Q.-X*., Peng, Y.-G., Zhang, J.-W., Song, L., Feng, Z., Gong, L.-Z*., Org. Lett. (IF2012 = 5.862), 2009, 11, 4620. Highly Enantioselective Oxidative Couplings of 2-Naphthols Catalyzed by Chiral Bimetallic Oxovanadium Complexes with Either Oxygen or Air as Oxidant. Guo, Q.-X., Wu, Z.-J., Luo, Z.-B., Liu, Q.-Z., Ye, J.-L., Luo, S.-W., Cun, L.-F., Gong, L.-Z*, J. Am. Chem. Soc. (IF2012 = 10.677), 2007, 129, 13927. Chiral Brønsted Acid-Catalyzed Direct Asymmetric Mannich Reaction. Guo, Q.-X., Liu, H., Guo, C., Luo, S.-W., Gu, Y., Gong, L.-Z*. J. Am. Chem. Soc. (IF2012 = 10.677), 2007, 129, 3790.

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