个人简介
教育背景
2002-09~2006-07年, 西北大学,学士,生物科学与技术基地班
2006-09~2007-07年, 约克大学,硕士, 功能基因组学
2007-09~2011-06年, 约克大学,博士,化学 (导师: Gideon Davies 院士)
工作经历
2011-11~2013-03 年, Scripps Research Institute (美国),博士后 (导师: Jim Paulson 教授)
2013-06~2020-07 年, 西北大学 化学与材料科学学院,副教授
研究领域
酶催化反应机理及活性调控;纳米酶;微量热;结构生物学
近期论文
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Wasey, A., J. Yang, D. Sun, Y. He*, and C. Zhang*.On-chip Carba NP test for accurate and high throughput detection of carbapenemase-producing Enterobacteriaceae..Talanta.2020-01-01,210,120656
Xiong, R., W. Zhang, Y. Zhang, Y. Zhang, Y. Chen, Y. He*, and H. Fan*,.Remote and real time control of an FVIO-enzyme hybrid nanocatalyst using magnetic stimulation.Nanoscale.2019-01-01,11(39) ,18081-18089
Zhang, Y., J.E. Lei, Y. He*, J. Yang, W. Wang, A. Wasey, J. Xu*, Y. Lin, H. Fan, G. Jing, C. Zhang, and Y. Jin. Label-free visualization of carbapenemase activity in living bacteria.. Angew Chem Int Ed.2018-01-01, 57(52),17120-17124
Xiang, Y., C. Chen, W.M. Wang, L.W. Xu, K.W. Yang*, P. Oelschlaeger, and Y. He*.Rhodanine as a potent scaffold for the development of broad-spectrum metallo-beta-lactamase inhibitors..ACS Med Chem Lett.2018-01-01,9(4),359-64
Wang, Q., Y. He*, R. Lu, W.M. Wang, K.W. Yang*, H.M. Fan, Y. Jin, and G.M. Blackburn.Thermokinetic profile of NDM-1 and its inhibition by small carboxylic acids.Biosci Rep.2018-01-01,38(2),BSR20180244
Wang, W.J., Q. Wang, Y. Zhang, R. Lu, Y.L. Zhang, K.W. Yang*, J.E. Lei, and Y. He*.Characterization of beta-lactamase activity using isothermal titration calorimetry.Biochim Biophys Acta-Gen Subj.2017-01-01,1861(8),2031-38