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导师所发表文章(仅列第一或通讯作者)
[1]LZhou,JHRen,STCheng,HMXu,WXChen,DPChen,VKWWong,BYKLaw,YLiu,XFCai,HTang,HBYu,JLHu,YHu,HZZhou,FRen,LHe,ZWHu,HJiang,HYXu,ALHuang*,JChen*.AfunctionalvariantinUBE2L3contributestoHBVinfectionandmaintainscccDNAstabilitybyinducingdegradationofAPOBEC3Aprotein.Hepatology201969(5):1885-1902共同通讯作者(IF:14.97)
[2]JHRen,JLHu,STCheng,HBYu,KWWong,BYLaw,YFYang,YHuang,YLiu,WXChen,XFCai,HTang,YHu,WLZhang,XLiu,QXLong,LZhou,NNTao,HZZhou,QXYang,FRen,LHe,RGong,ALHuang*,JChen*.SIRT3restrictshepatitisBvirustranscriptionandreplicationthroughepigeneticregulationofcovalentlyclosedcircularDNAinvolvingsuppressorofvariegation3-9homolog1andSETdomaincontaining1Ahistonemethyltransferases.Hepatology2018;68(4):1260-1276.共同通讯作者(IF:14.97)
[3]JChen,AWChan,KFTo,WChen,ZZhang,JHRen,CLSong,YSCheung,PBLai,SHCheng,MHNg,ALHuang*,BCKo*.SIRT2overexpressioninhepatocellularcarcinomamediatesepithelialtomesenchymaltransitionbyProteinKinaseB/GlycogenSynthaseKinase-3β/β-CateninSignaling.Hepatology2013;57(6):2287-2298.第一作者(IF:14.97)
[4]LKRan,YChen,ZZZhang,NNTao,JHRen,LZhou,HTang,XChen,KChen,WYLi,ALHuang*,JChen*.SIRT6overexpressionpotentiatesapoptosisevasioninhepatocellularcarcinomaviaBCL2-associatedXprotein-dependentapoptoticpathway.ClinicalCancerResearch2016;22(13):3372-3382.共同通讯作者(IF:10.199)
[5]JChen,BZhang,NWong,WILo,KFTo,WHChan,HLNg,YSHo,SHCheng,BSLai,JYu,HKNg,MTLing,ALHuang,XFCai,andBCKo*.Sirtuin1(SIRT1)isupregulatedinasubsetofhepatocellularcarcinomaandisessentialfortumorcellgrowth.CancerResearch2011,71(12),4138-4149.第一作者(IF:9.13)
[6]CLSong,HTang,LKRan,BCKo,ZZZhang,XChen,JHRen,NNTao,WYLi,ALHuang*,JChen*.Sirtuin3inhibitshepatocellularcarcinomagrowththroughtheglycogensynthasekinase-3β/BCL2-associatedXprotein-dependentapoptoticpathway.Oncogene2016;35(5):631-641.共同通讯作者(IF:6.854)
[7]WYLi,HZZhou,YChen,XFCai,HTang,JHRen,VKWWong,BYKLaw,YChen,STCheng,HBYu,HYCai,WXChen,NTang,WLZhang,NNTao,QXYang,FRen,LHe,HJiang,ALHuang*,JChen*.NAD(P)H:quinoneoxidoreductase1overexpressioninHepatocellularCarcinomapotentiatesapoptosisevasionthroughregulatingstabilizationofX-linkedinhibitorofapoptosisprotein.CancerLetters2019451:156-167共同通讯作者(IF:6.491)
[8]QXYang,SZhong,LHe,XJJia,HTang,STCheng,JHRen,HBYu,LZhou,HZZhou,FRen,ZWHu,RGong,ALHuang,JChen*.PBKoverexpressionpromotesmetastasisofhepatocellularcarcinomaviaactivatingETV4-uPARsignalingpathway.CancerLetters2019451:156-167共同通讯作者(IF:6.491)
[9]LWang#,JChen#,YZeng,JWei,JJJing,GLi,LSu,XJTang,TCWu,LZhou.FunctionalVariantintheSLC22A3-LPAL2-LPAGeneClusterContributestotheSeverityofCoronaryArteryDisease.ArteriosclerosisThrombosisandVascularBiology2016;36(9):1989-1996.共同第一作者(IF:6.086)
[10]JHRen,YTao,ZZZhang,WXChen,KChen,CLSong,LKRan,WYLi,ALHuang*,JChen*.Sirtuin1(SIRT1)regulatesHBVtranscriptionandreplicationbytargetingtranscriptionfactorAP-1.JournalofVirology2014;88(5):2442-2451.共同通讯作者
[11]CLSong,JHRen,LKRan,YGLi,XSLi,XChen,WYLi,ALHuang*,JChen*.CyclinD2playsaregulatoryroleinHBVreplication.Virology2014,462-463:149–157.共同通讯作者
[12]YWWang,XFShan,ZLiang,YLShan,WHuang,DZhang,AZZen,XZhou,YZhao,XYGong,GXu,XZhang,JChen*,ALHuang*.DeepSequencingAnalysisofHBVGenotypeShiftandCorrelationwithAntiviralEfficiencyduringAdefovirDipivoxilTherapy.PLoSONE2015;10(6):e0131337.共同通讯作者
[13]QFu#,XTang#,JChen#,LSu,MZhang,LWang,JJing,LZhou.EffectsofPolymorphismsinAPOA4-APOA5-ZNF259-BUD13GeneClusteronPlasmaLevelsofTriglyceridesandRiskofCoronaryHeartDiseaseinaChineseHanPopulation.PLoSONE2015;10(9):e0138652.共同第一作者
[14]TZeng#,DWang#,JChen#,YTian,XCai,HPeng,LZhu,ALHuang*,HTang*.LncRNA-AF113014promotestheexpressionofEgr2byinteractionwithmiR-20atoinhibitproliferationofhepatocellularcarcinomacells.PLoSONE2017;12(5):e0177843.共同第一作者
[15]STCheng,HTang,JHRen,XChen,ALHuang*,JChen*.Interleukin-34inhibitshepatitisBvirusreplicationinvitroandinvivo.PLoSOne2017;12(6):e0179605.共同通讯作者
[16]JHRen,XChen,LZhou,NNTao,HZZhou,BLiu,WYLi,ALHuang*,JChen*.ProtectiveRoleofSirtuin3(SIRT3)inOxidativeStressMediatedbyHepatitisBVirusXProteinExpression.PLoSONE2016;11(3):e0150961.共同通讯作者
[17]YCao#,JChen#,DWang,HPeng,XTan,DXiong,ALHuang,HTang*.UpregulatedinHepatitisBvirus-associatedhepatocellularcarcinomacells,miR-331-3ppromotesproliferationofhepatocellularcarcinomacellsbytargetingING5.Oncotarget2015;6(35):38093-106.共同第一作者
[18]TaoNN,ZhouHZ,TangH,CaiXF,ZhangWL,RenJH,ZhouL,ChenX,ChenK,LiWY,LiuB,YangQX,ChengST,HuangLX,HuangAL*,ChenJ*.Sirtuin3enhanceddrugsensitivityofhumanhepatomacellsthroughglutathioneS-transferasepi1/JNKsignalingpathway.Oncotarget20162;7(31):50117-50130.共同通讯作者
[19]NNTao,JHRen,HTang,LKRan,HZZhou,BLiu,ALHuang*,JChen*.DeacetylationofKu70bySIRT6attenuatesBax-mediatedapoptosisinhepatocellularcarcinoma.BiochemBiophysResCommun2017;485(4):713-719.共同通讯作者
[20]STCheng,HRen,XFCai,HJiang,JChen*.HBx-elevatedSIRT2promotesHBVreplicationandhepatocarcinogenesis.BiochemBiophysResCommun201812;496(3):904-910.通讯作者
[21]STCheng,DYuan,YLiu,YHuang,XChen,HBYu,LHe,HJiang,JHRen,JChen*.Interleukin-35LevelIsReducedinPatientswithChronicHepatitisBVirusInfection.InternationalJournalofMedicalSciences2018;15(2):188-194.通讯作者
[22]ZZhang#,JChen#,YHe,XZhan,RZhao,YHuang,HXu,ZZhu,QLiu.miR-125binhibitshepatitisBvirusexpressioninvitrothroughtargetingoftheSCNN1Agene.ArchivesofVirology2014;159(12):3335-3343.共同第一作者
[23]YuHB,JiangH,ChengST,HuZW,RenJH,ChenJ*.AGK2,ASIRT2Inhibitor,InhibitsHepatitisBVirusReplicationInVitroAndInVivo.IntJMedSci20187;15(12):1356-1364.通讯作者
[24]WYLi,JHRen,NNTao,LKRan,XChen,HZZhou,BLiu,XSLi,ALHuang,JChen*.TheSIRT1inhibitor,nicotinamide,inhibitshepatitisBvirusreplicationinvitroandinvivo.ArchivesVirology2016;161(3):621-630.通讯作者
[25]LXu,ZTu,GXu,YWang,WLPan,XZhan,QLuo,YHuang,JChen*,ALHuang*.EpirubicindirectlypromoteshepatitisBvirus(HBV)replicationinstableHBV-expressingcelllines:anovelmechanismofHBVreactivationfollowinganticancerchemotherapy.MolecularMedicineReports2014;9(4):1345-1350.共同通讯作者