白泉 - 西北大学 - 化学与材料科学学院

研究领域

主要从事现代分离科学理论、生物大分子的分离纯化、蛋白质组学、蛋白折叠及基因工程产品下游生产工艺的最优化研究。目前主要从事现代分离科学理论、生物大分子的分离纯化、蛋白质组学、蛋白折叠及基因工程产品下游生产工艺的最优化研究，以及与此相关的新技术、新理论、新材料和新工艺研究。在理论研究、应用研究及高技术产业化方面取得了一系列创新性成果。

近期论文

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Quan Bai,Gang Chen,Jianbo Liu,Xindu Geng,Renaturation and Purification of rhGM-CSF with Ion-Exchange Chromatography,Biotechnol.Prog.2007,23,1138-1142 Quan Bai,Yu Kong,Xin-du Geng,Studies on Renaturation with Simultaneous Purification of Recombinant Human Proinsulin from E.coli with High Performance Hydrophobic Interaction Chromatography，J Liquid Chromatogr.&Related Tech.,2003,26(5),683-695 Quan Bai,Xindu Geng,Studies on the Thermodynamics During the Biopolymers Retention Process in Reversed-phase Liquid Chromatography.I.The Free Energy Change and Its Fractions,Adsorption and Desorption Free Energy Changes,J Liquid Chromatogr.&Related Tech.,2003,26(19):3199-3215 Xindu Geng,Quan Bai,Yangjun Zhang,Xiang Li,Dan Wu,Refolding and purification of interferon-gamma in industry by hydrophobic interaction chromatography,J Biotech,2004,113:137-149 Quan Bai,Yu Kong,Cuihua Dong,Xindu Geng,Studies on the Refolding of the Reduced-denatured Insulin With Size Exclusion Chromatography,Science in China(Ser.B),2005,48(supp.),55-59 Quan Bai,Xindu Geng,The temperature convergence of biopolymers in reversed-phase liquid chromatography,Chromatographia,2001,54,35-338 耿信笃，白泉，用疏水色谱复性并同时纯化蛋白质的机理及其应用，中国科学，2002，32(5):460-471 GENG Xindu，BAI Quan，Mechanism of simultaneously refolding and purification of proteins by hydrophobic interaction chromatographic unit and applications，Science in China(Ser.B),2002,45(6):655-669 白泉，耿信笃，化学学报，反相液相色谱中生物大分子保留自由能及相比的测定，2002，60,870-875 白泉，孔宇，耿信笃，用疏水色谱对还原胍变性牛胰岛素的折叠特性研究，高等学校化学学报，2002，23，1483~1488 CHEN Gang,GONG Bo-Lin,BAI Quan,GENG Xin-Du,Preparation of Medium Cation Exchange Stationary Phase of Polymeric Matrix and Their Chromatographic Properties,Chinese Journal of Chemistry,2007,25,77—82 12.Xiaofeng Yang,Lu Li,Quan Bai,A highly selective and sensitive fluorescein-based chemodosimeter for Hg2+ions in aqueous media,Analytica Chimica Acta 584(2007)95–100 Xiaofeng Yang,Yesi Jie,Quan Bai,Xiaoqing Wang,A Fluorescein-based Fluorogenic Probe for Fluoride Ion Based on the Fluoride-induced Cleavage of tert-butyldimethylsilyl Ether,J Flouresc,2007,17:81-87 Ke congyu,Bai Quan,Geng xindu,Design and resolution of asimple-type column for renaturation with simultaneous purification of proteins and its application to lysozyme refolding,Chin.J Chromatogr.,2004,22:394-398 Yao Cong,Ke Congyu,Bai Quan,Wei Yinmao,Geng Xindu,A fast method for preparation of cytochrome-C of high purity from pig heart by hydrophobic interation chromatography,Chin.J Chromatogr.,2004,22:399-402 陈刚，白泉，耿信笃，伴刀豆球蛋白亲和色谱柱的制备及其在糖蛋白核糖核酸酶B结构分析中的应用，色谱，2006，24:425-431 Gang Chen,Quan Bai,Xindu Geng,Preparation of Concanavalin AImmobilized Affinity Chromatographic Packings Based on Silica Matrix and Structure Analysis of Glycoprotein with MALDI-TOF Mass Spectrometer,Chin JChromatogr,2006,24(5):425–431 Yehua Shen,Quan Bai,Yangjun Zhang,et al,A Novel Method for Diminishing Protein Aggregation During Denatuaration Process.Chin Chem Let.2006,17(3):395-398. Xindu Geng,Quan Bai,Renaturation and Simultaneous Purification of Unfolded Proteins,American Biotechnology Laboratory,2003,21(12):32-34 Quan BAI,Yu KONG,Xindu GENG，Stdies on Simultaneous Renaturation and Purification of Recombinant Human Proinsulin with Semi-Preparative Scale，Chinese Chemical Letters,2003,14(8):824-827