研究领域
生物化学、化学生物学、分离科学
方向一:蛋白质化学
蛋白质复性研究是生命科学领域的前沿课题,重组蛋白药物的研究具有重要的科学价值和应用前景。主要从事重组蛋白的表达、纯化、复性及结构解析的理论与技术研究,并从事基质金属蛋白酶抑制剂与抗癌机理研究。
方向二:资源化学
1)沙生植物产业化开发:以沙生木本油料植物长柄扁桃为核心从事沙生植物产业化开发研究,并探索“多方位立体化可持续性沙漠治理新模式”。
2)生物柴油新技术研究:以自主开发的新型生物柴油固体催化剂为技术核心,开发生物柴油新技术。
近期论文
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Yehua Shen,Xiaofeng Yang,Yao Wu,Li Cong,Sensitive sepctrofluorimetric determination of Cytochrome cwith spirocyclic rhodamine Bhydrazide in micellar medium,J Fluoresc.,2008,18:163–168
Shen Yehua,Yang Xiao-Feng,Jin Lihua.Fluorimetric determination of iodate based on cyclodesulfurization of thiosemicarbazide with incorporated fluorescein[J].Chemia Analityczna,2008,53(4):597-607
Yehua Shen,Yuki Takayama,Yinmao Wei,Erisa Harada,Eiichi Nakatani,Hideo Akutsu,Refolding of mis-folded recombinant Cytochrome c3 with strong cation exchange chromatography,J.Liq.Chromatogr.Relat.Tech.,2007,30:1051-1059
SHEN Yehua,WANG Haibo,BAI Quan,GENG Xingdu,Effect of ligand structure of stationary phase in high performance hydrophobic interaction chromatography on renaturation efficiency of GuHCl-denatured-Chymotrypsin,Sci.Chin.(Ser.B),2005,48(supp):33-36
Jin-gang Yang,Ye-hua Shen,Yuan Hong,Feng-hai Jin,Shu-hua Zhao,Ming-cui Wang,Xiu-juan Shi,Xue-xun Fang.Stir-baked Fructus gardeniae(L.)extracts inhibit matrix metalloproteinases and alter cell morphology[J].Journal of Ethnopharmacology,2008,117:285~289
Yuki Takayama,Yehua Shen,Hideo Akutsu,Process of maturation of tetraheme Cytochrome c3 in aShewanella expression system,J.Biochem.,2007,141:121-126,封面文章
Bolin Gong,Yehua Shen,Xingdu Geng,Preparation of strong cation exchange packing based on monodispere poly(Glycidyl Methacrylate–co–Ethylenedimethacry-Late)particles and their application,J.Liq.Chromatogr.Relat.Tech.,2003,6:963-976 4.成果鉴定