个人简介

1998年-2008年在四川大学学习获学士硕士和博士学位，师从冯小明院士。研究方向为不对称合成及其在药物合成中的应用，致力于手性药物及中间体的新型合成方法及新型手性先导化合物的探索。

研究领域

不对称合成及其在药物合成中的应用

科研项目 1)国家自然科学基金面上项目（21672031，负责人） 2)重庆市教委科技项目（KJ1500221，负责人） 3）药学院青年师资培养项目（YXY2014QNSZ01，负责人） 4)重庆市科委基础与前沿研究一般项目（cstc2013jcyjA10144,负责人） 5)国家自然科学基金青年项目（20902114，负责人）

近期论文

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17)MouxiongLiu,DongdongGui,PingDengandHuiZhou*,“AsymmetricHenryReactionof2-AcylpyridineN-OxidesCatalyzedbyaNi-AminophenolSulfonamideComplex:AnUnexpectedMononuclearCatalyst”Molecules2019,24,1471. 16)JunhaoJiang,HuiZhou,QihuaJiang,LiliSunandPingDeng*,“NovelTransformingGrowthFactor-BetaReceptor1AntagoniststhroughaPharmacophore-BasedVirtualScreeningApproach”Molecules2018,23,2824. 15)GuanghuiChen,GuojuanLiang,YiwuWang,PingDeng,HuiZhou*,“AhomodinuclearcobaltcomplexforthecatalyticasymmetricMichaelreactionofβ-ketoesterstonitroolefins”Org.Biomol.Chem.2018,16,3841-3850. 14)FeilongHe,GuanghuiChen,JunxiaYang,GuojuanLiang,PingDeng,YanXiong,HuiZhou*,“CatalyticenantioselectiveHenryreactionofα-ketoesters,2-acylpyridinesand2-acylpyridineN-oxides”RSCAdv.2018,8,9414-9422. 13)JingZhou,GuojuanLiag,XiangnanHu,LipingZhou,HuiZhou*,“Facilesynthesisof3-aryl2,3-dihydrobenzofuransvianoveldomino1,6-addition/O-alkylationreactionsofpara-quinonemethides”Tetrahedron,2018,74,1492-1496. 12)ShixiongZhang,PingDeng,JingZhou,MouxiongLiu,GuojuanLiang,YanXiong,HuiZhou*,“AnovelhomobimetallicnickelcomplexfortheasymmetricdirectMannichreactionofimines:apracticalmethodonamulti-gramscale”Chem.Commun.2017,53,12914-12917.(HighlightedbySynfacts,2018,14,285) 11)YoumaoZeng,PingDeng,ShixiongZhang,HongYan,GuojuanLiang,YanXiong,HuiZhou*,“AnNi-PyBisulidineComplexfortheAsymmetricHydrophosphonylationofAldehydes”Org.Biomol.Chem.2016,14,9221-9224. 10)YangLi,PingDeng,YoumaoZeng,YanXiong,HuiZhou*,“anti-SelectiveAsymmetricHenryReactionCatalyzedbyaHeterobimetallicCu-Sm-AminophenolSulfonamideComplex”Org.Lett.2016,18,1578-1581. 9)YajunLiu,PingDeng,XiangyangLi,YanXiong,HuiZhou*,“AsymmetricHenryReactionCatalyzedbyaChiralDinuclearNickelComplex”Synlett,2014,25,1735-1738.(HighlightedbySynfacts,2014,10,1045) 8)TaoWang,RuiTian,BinXiao,YiShen,HuiZhou*,QingengLi*,“ANovelSynthesisofIbutilideFumarate”Lett.Org.Chem.2011,8,423-426. 7)HuiZhou,DahaiChen,HongweiGao,QingengLi*,“AMildandConvenientSemi-SynthesisofDocetaxelfrom10-DeacetylBaccatinIII”Lett.Org.Chem.,2010,7,450-452. 6)HuiZhou,DanPeng,BoQin,ZongruiHou,XiaohuaLiu,XiaomingFeng*,“HighlyEnantioselectiveAzaHenryReactionofN-tosyliminesCatalyzedbyN,N-dixoide-Cu(I)Complex”J.Org.Chem.,2007,72,10302-10304. 5)DanPeng,HuiZhou,XiaohuaLiu,LiweiWang,ShikuiChen,XiaomingFeng*“EnantioselectiveCyanoformylationofAldehydesCatalyzedbyaChiralQuaternaryAmmoniumSaltandTriethylamine”Synlett,2007,15,2448–2450. 4)Shi-KuiChen,DanPeng,HuiZhou,Li-WeiWang,Fu-XueChen,Xiao-MingFeng*“HighlyEnantioselectiveCyanoformylationofAldehydesCatalyzedbyaMononuclearSalen-Ti(OiPr)4ComplexProducedInSitu”Eur.J.Org.Chem.2007,639–644. 3)Fu-XueChen,HuiZhou,XiaohuaLiu,BoQin,XiaomingFeng,*GuolinZhang,YaozhongJiang,“EnantioselectiveCyanosilylationofKetonesbyaCatalyticDoubleActivationMethodwithanAluminiumComplexandanN-Oxide”Chem.Eur.J.2004,10,4790–4797. 2)Fu-XueChen,XiaohuaLiu,BoQin,HuiZhou,XiaomingFeng,*GuolinZhang,“HighlyEfficientDouble-ActivationCatalystsfortheSynthesisofKetoneCyanohydrins”Synthesis2004,14,2266–2272. 1)HuiZhou,FuxueChen,BoQin,XiaomingFeng*,GuolinZhang,“CyanosilylationofKetonesCatalyzedbyQuaternaryAmmoniumSaltandN-oxide”Synlett,2004,1077-1079.