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个人简介

2019至今,西安交通大学,生命科学与技术学院,教授,博导 2017-2018,西安交通大学,生命科学与技术学院,副教授,博导 2016-2017,日本东北大学,原子分子材料科学高等研究所,访问学者 2011-2017:西安交通大学,理学院,副教授 2010-2011,纳尔科(中国)环保技术有限公司,高级化学工程师 2009-2010,美国天普大学,化学系,博士后 2008-2009,瑞士洛桑联邦理工大学,化学与化工学院,博士后 2004-2007,英国华威大学,化学系,博士(化学) 2001-2004,中国科学院长春应用化学研究所,电分析国家重点实验室,硕士(分析化学) 1997-2001,西北大学,化学系,学士(化学)

研究领域

生物电分析化学(单细胞光电分析与成像,细胞微环境研究) 柔性即时检测芯片与器件(纸基电化学即时检测芯片、柔性电子材料与器件的研发)

近期论文

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J.C. Niu, W.J. Liu, J.X.Z. Li, X.L. Pang, Y.L. Liu, C. Zhang, K.Y. Yue, Y.L. Zhou, F. Xu, X.G. Li*, F. Li*, Machining water through laser cutting of water in liquid pancake, Nature Communications, 2023, 2023, 14, 3853. Y. L. Zhou#, J. C. Niu#, B. Peng#, Y. Zhou, F. Li*, Liquid plasticine-based electrokinetic enrichment of proteins, ChemistryOpen, 2023, 12, e202200259. T. Zhu, J. J. Song, B. Gao, J. J. Zhang, Y. B. Li, Z. Y. Ye, Y. X. Zhao, X. G. Guo, F. Xu, F. Li*, Effect of extracellular matrix stiffness on Candesartan efficacy in anti-fibrosis and antioxidation, Antioxidants, 2023, 12(3), 679. Z. Y. Ye, Y. B. Li, Y. X. Zhao, J. J. Zhang, T. Zhu, F. Xu, F. Li*, Effect of exogenous electric stimulation on cardiac tissue function in situ monitored by scanning electrochemical microscopy, Analytical Chemistry, 2023, Accepted Y.X. Zhao, Y.B. Li, S. Kuermanbayi, Y.L. Liu, J.J. Zhang, Z.Y. Ye, H. Guo, K. Qu, F. Xu, F. Li*, In situ and quantitatively monitoring dynamic process of ferroptosis in single cancer cell by scanning electrochemical microscopy, Analytical Chemistry, 2023, 95, 3, 1940. J. J. Zhang, Y. L. Liu, Y. B. Li, T. Zhu, J. B. Qiu, F. Xu, H. Zhang, F. Li*, In situ and quantitatively imaging of heat-induced oxidative state and oxidative damage of living neurons using scanning electrochemical microscopy, Small Methods, 2022, 2200689 Y. C. Li#, Y. N. Liu#, B. Peng#, X. Y. Li, T. S. Fang, S. Liu, J. C. Liu, B. Li, F. Li*, Stretchable, conductive, breathable and moisture-sensitive e-skin based on CNTs/graphene/GelMA mat for wound monitoring, Biomaterials Advances, 2022, Accepted. M. L. He#, L. Feng#, Y. Chen#, B. Gao#, Y. W. Du, L. Zhou, F. Li*, H. B. Liu*, Polydatin attenuates tubulointerstitial fibrosis in diabetic kidney disease by inhibiting YAP expression and nuclear translocation, Frontiers in Physiology, 2022, DOI: 10.3389/fphys.2022.927794 Y. Zhou, J. J. Zhang, Y. X. Zhao, Y. L. Liu, F. Li*, Bacterial Biofilm Probed by Scanning Electrochemical Microscopy: A Review, ChemElectroChem, 2022, DOI: 10.1002/celc.202200470 S. Kuermanbayi#, Y. W. Yang#, Y. X. Zhao, Y. B. Li, L. Wang, J. Yang, Y. Zhou, F. Xu*, F. Li*, In situ monitoring of functional activity of extracellular matrix stiffness-dependent multidrug resistance protein 1 using scanning electrochemical microscopy, Chemical Science, 2022, DOI: 10.1039/D2SC02708A Y. B. Li, Z. Y. Ye, J. J. Zhang, Y. X. Zhao, T. Zhu, J. J. Song, F. Xu, F. Li*, In situ and quantitative monitoring of cardiac tissues using programmable scanning electrochemical microscopy, Analytical Chemistry, 2022, Accepted Y. L. Liu#, Y. X. Zhao#, Y. B. Li, Z. Y. Ye, J. J. Zhang, Y. Zhou, T. Y. Gao, F. Li*, Recent advances of nanoelectrodes for single-cell electroanalysis: from extracellular, intercellular to intracellular, Journal of Analysis and Testing,, 2022, 6, 178–192 Z. D. Li, S. Wu, J. C. Ji, Y. M. Bai, P. P. Jia, Y. Gong, S. S. Feng, F. Li*, Ball Pen Writing without Ink: A Truly Simple and Accessible Method for Sensitivity Enhancement in Lateral Flow Assays, RSC Advances, 2022, Accepted 86) B. Li*, Y. H. Wu, Y. Sun, W. T. Ma, L. Jiang, Z. C. Yang, F. Li, G. M. Chen*, Patterning coexisted micro/nano structures for consequential camouflage via mechanical constraint harnessed surface instability, Applied Physics Letters, 2021, 119(26), DOI: 10.1063/5.0079596. L. Cao, X. J. Guo, P. Mao, Y. L. Ren, Z. D. Li, M. L. You, J. Hu, M. Tian, C. Y. Yao, F. Li, F. Xu*, A Portable Digital Loop-Mediated Isothermal Amplification Platform Based on Microgel Array and Hand-Held Reader, ACS Sensors, 2021, 6(10), 3564–3574. R. Y. He#, H. Liu#, T. S. Fang, Y. Niu, H. Q. Zhang, F. Han, B. Gao, F. Li*, F. Xu*, A Colorimetric Dermal Tattoo Biosensor Fabricated by Microneedle Patch for Multiplexed Detection of Health-related Biomarkers, Advanced Science, 2021, 2103030. J. X. Lang#, Y. B. Li#, Z. Y. Ye, Y. W. Yang, F. Xu, G. Y. Huang, J. J. Zhang, F. Li*, Investigating the effect of substrate stiffness on redox state of cardiac fibroblasts using scanning electrochemical microscopy, Analytical Chemistry, 2021, 93(14), 5797–5804. Y. B. H. Jiao, J. Zhuang*, Z. D. Li, L. Cao, F. Xu, F. Li, Q. Q. Zheng, Z. J. Gao, Analysis and improvement of positioning reliability and accuracy of theta pipette configuration for scanning ion conductance microscopy, Ultramicroscopy, 2021, 224, 113240. W. H. He#, M. L. You#, Z. D. Li, L. Cao, F. Xu, F. Li*, A. Li*, Upconversion nanoparticles-based lateral flow immunoassay for point-of-care diagnosis of periodontitis, Sensors and Actuators: B. Chemical, 2021, 334, 129673 J. C. Niu, Z. H. Bao, Z. N. Wei, J. X. Z. Li, B. Gao, X. F. Jiang*, F. Li*, A Three-Dimensional Paper-Based Isoelectric Focusing Device for Direct Analysis of Proteins in Physiological Samples, Analytical Chemistry, 2021, 93(8), 3959-3967 R. H. Tang, L. N. Liu, M. Li, X. Yao, Y. W. Yang, S. F. Zhang*, F. Li*, Transparent Microcrystalline Cellulose/Polyvinyl Alcohol Paper as New Platform for 3D Cell Culture, Analytical Chemistry, 2020, 92(20), 14219–14227. X. J. Guo, Y. B. Li, Y. C. Li, Z. Y. Ye, J. J. Zhang, T. Zhu, F. Li*, An L012@PAni-PAAm hydrogel composite based-electrochemiluminescence biosensor for in situ detection of H2O2 released from cardiomyocytes, Electrochemica Acta, 2020, 354, 136763. J. J. Zhang#, T. Zhu#, J. X. Lang, W. X. Fu, F. Li*, Recent advances of scanning electrochemical microscopy and scanning ion conductance microscopy for single cell analysis, Current Opinion in Electrochemistry, 2020, 22, 178-185 M. Wang#, Y. W. Yang#, L. C. Han#, S. Han, N. Liu, F. Xu. Li*, F. Li*, Effect of three-dimensional ECM stiffness on cancer cell migration through regulating cell volume homeostasis, Biochemical and Biophysical Research Communications, 2020, 528, 459-465. J. C. Niu, H. X. Shi, H. G. Wei, B. Gao, J. Li, F. Xu, X. G. Li*, F. Li*, Liquid Plasticine Integrated with Isoelectric Focusing for Miniaturized Protein Analysis, Analytical Chemistry, 2020,2, 9048-9056 Y. C. Li, C. R. Zheng, S. Liu, L. Huang, T. S. Fang, J. Li, F. Xu, F. Li*, A Smart Glove Integrated with Tunable MWNTs/PDMS Fibers Made of One-Step Extrusion Method for Finger Dexterity, Gesture and Temperature Recognition, ACS Applied Materials & Interfaces, 2020, 12, 21, 23764–23773. Y. B. Li#, J. X. Lang#, Z. Y. Ye, M. Wang, Y. W. Yang, X. J. Guo, J. Zhuang, J. J. Zhang, F. Xu, F. Li*, Effect of substrate stiffness on redox state of single cardiomyocyte: a scanning electrochemical microscopy study, Analytical Chemistry, 2020, 92, 7, 4771-4779 R. Y. He, Y. Niu, Z.D. Li, A. Li, H. Y. Yang, F. Xu, F. Li*, A Hydrogel Microneedle Patch for Point-of-Care Testing Based on Skin Interstitial Fluid, Advanced Healthcare Materials, 2020, 9, 1901201. M. Wang, Y. W. Yang, F. Xu, F. Li*, Cell mechanical microenvironment for cell volume regulation, Journal of Cellular Physiology, 2020, 235, 4070–4081. F. Li#, M. L. You#, S. X. Li#, J. Hu, Y. Gong, C. Liu, H. Y. Yang*, F. Xu*, Paper-based point-of-care immunoassays: recent advances and emerging trends, Biotechnology Advances, 2020, 39, 107442. H. Liu, M. X. Li, S. B. Liu, P. P. Jia, X. J. Guo, S. S. Feng, T. J. Lu, H. Y. Yang,, F. Li*, F. Xu*, Spatially Modulated Stiffness on Hydrogel for Soft and Stretchable Integrated Electronics, Material Horizons, 2020, 7, 203. 曹雷, 郭丽娟, 郭晓锦, 巩燕, 李菲*, 基于数字PCR技术的DNA甲基化检测及其在癌症液体活检中的应用进展, 生物物理与生物化学进展, 2019, 46(11), 1085-1100 M. Wang, B. Cheng, Y. W. Yang, H. Liu, G. Y. Huang, L. C. Han, F. Li*, F. Xu*, Microchannel stiffness and confinement jointly induce the mesenchymal-amoeboid transition of cancer cell migration, Nano Letters, 2019, 19, 9, 5949-5958 S. F. Zhang, L. N. Liu, R. H. Tang, Z. Liu, X. C. He, Z. G. Qu, F. Li*, Sensitivity enhancement of lateral flow assay by embedding cotton threads in paper, Cellulose, 2019, 26(13–14), 8087–8099. R.H. Tang, L. N. Liu, S. F. Zhang, X. C. He, X. J. Li, F. Xu, Y. H. Ni*, F. Li*, Advances in modification approaches for paper-based point-of-care testing, Microchimica Acta, 2019, 186:521 Y. C. Li, Z. D. Li, H. Liu, S. Y. Chen, X. J. Guo, M. Lin, F. Li*, A portable electrochemical platform integrated with a 3D AuNPs/CNTs sponge for point-of-care testing of neurotransmitters, Journal of The Electrochemical Society, 2019, 166(6), B524-B531 Y. Gong, Y. M. Zheng, B. R. Jin, M. L. You, J. Y. Wang, X. J. Li, M. Lin, F. Xu, F. Li*, A portable and universal upconversion nanoparticle-based lateral flow assay platform for point-of-care testing, Talanta, 2019, 201, 126-133 Y. C. Li, R. Y. He, Y. Niu, F. Li*, Paper-based electrochemical biosensors for point-of-care testing of neurotransmitters, Journal of Analysis and Testing, 2019, 3, 19-36 郎瑾新,李亚北,杨耀维,焦阳博翰,王蒙,庄健,李菲*, 扫描离子电导显微镜在细胞表征中的应用研究, 中国科学:化学, 2019, DOI:10.1360/N032018-00266. M. Wang, S. B. Liu, F. Li*, Imaging oxygen microenvironment in hydrogel microwell array, Acta Mechanica Sinica, 2019, 35(2):321-328 Y. Sun, F. Li*, Z. C. Shen, Y. B. Li, J. X. Lang, W. M. Li, G. X. Gao, S. J. Ding, C. H. Xiao, T. Matsue, NiCoO2@CMK-3 composite with nanosheets-mesoporous structure as an efficient oxygen reduction catalyst, Electrochimica Acta, 2019, 294, 38-45. Z. D. Li, H. Liu, X. C. He, F. Xu, F. Li*, Pen-on-paper strategies for point-of-care testing of human health, Trac-Trends in Analytical Chemistry, 2018, DOI: 10.1016/j.trac.2018.08.010. H. Liu, M. X. Li, C. Ouyang, T. J. Lu, F. Li*, F. Xu*, Bio-Friendly, Stretchable and Reusable Hydrogel Electronics as Wearable Force Sensors, Small, 2018, 14(36): e1801711 W. H. He#, M. L. You#, W. T. Wan, F. Xu, F. Li*, F. Li*, Point-of-Care Periodontitis Testing: Biomarkers, Current Technologies and Perspectives, Trends in Biotechnology, 2018, DOI: doi.org/10.1016/j.tibtech.2018.05.013. X. Y. Cui#, L. Cao#, Y. L. Huang, S. Huang, D. Bai, M. Lin, Q. Z. Yang, T. J. Lu, F. Xu, F. Li*, n Vitro Diagnosis of DNA Methylation Biomarkers with Digital PCR in Breast Tumors, Analyst, 2018, 143, 3011. J. Zhuang, Y. B. Jiao, Z.Q. Li, J.X. Lang, F. Li*, A Continuous Control Mode with Improved Imaging Rate for Scanning Ion Conductance Microscope (SICM), Ultramicroscopy, 2018, 190, 66. H. Liu, M. X. Li, Y. H. Li, H. Yang, A. Li, T. J. Lu, F. Li, F. Xu*, Magnetic steering of liquid metal mobiles, Soft Matter, 2018, 14, 3236. C. H. T. Yew, P. Azari, J. R. Choi, F. Li*, B. Pingguan-Murphy*, Electrospin-coating of nitrocellulose membrane enhances sensitivity in nucleic acid-based lateral flow assay, Analytica Chimica Acta, 2018, 1009, 81. M. Wang#, N. Chai#, B. Y. Sha, M. Y. Guo, J. Zhuang, F. Xu, F. Li*, The effect of substrate stiffness on cancer cell volume homeostasis, Journal of Cellular Physiology, 2018, 233(2), 1414–1423.

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