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个人简介

沈爱国,武汉大学化学与分子科学学院教授,博士生导师,中国物理学会光散射专业委员会副秘书长。2006年7月毕业于武汉大学化学与分子科学学院分析化学专业,获博士学位(导师:胡继明教授)。毕业后留校任教并连续3年赴德国不来梅Jacobs大学和韩国全南国立大学开展国际合作研究(每年3-4个月)。2008年12月晋升为副教授,2010年被遴选为博士生导师。2011年6月至2012年6月获德国DAAD-王宽诚博士后奖学金,在德国图宾根大学物理与理论化学所从事针尖增强拉曼光谱的合作研究(合作导师:Prof. Alfred J. Meixner和Dr. Dai Zhang)。2016年12月晋升为教授。现主要从事拉曼光谱的生化传感、生物成像及仪器研制等领域的研究工作。先后主持1项国家重大科学仪器设备开发项目,4项国家自然科学基金项目,1项中石油科技创新项目和2项国家重点实验室开放基金项目;参与1项国家自然科学基金仪器专项重点项目和1项国家重大研究计划培育项目。迄今已在Joournal of the American Chemical Society, Advanced Functional Materials, Analytical Chemistry 和 Chemical Communications等杂志上发表SCI源刊论文70余篇。

研究领域

1. 疾病(早期)诊断的拉曼光谱新技术与新仪器 2. 面向生物医学、食品、环境及刑侦等领域中微量特征物现场、快速分析的表面增强拉曼检测新原理和新器件 3. 新型表面增强拉曼光谱分子探针用于多元传感分析和生物成像

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen*, Ji-Ming Hu, Splicing nanoparticles-based ‘Click’ SERS could aid multiplex liquid biopsy and accurate cellular imaging, Journal of the American Chemical Society, 2018, 140, 10649-10652. Ai-Guo Shen, Li-Fang Chen, Wei Xie, Jun-Cheng Hu, Ao Zeng, Ryan M Richards, Ji-Ming Hu*, Triplex Au-Ag-C core-shell nanoparticles as a novel Raman labels, Advanced Functional Materials, 2010, 20, 969-975. Xiang-Ru Bai, Yi Zeng, Xiao-Dong Zhou, Xiao-Hua Wang, Ai-Guo Shen*, Ji-Ming Hu, Environmentally safe mercury (II) ions aided zero-background and ultrasensitive SERS detection of dipicolinic acid, Analytical Chemistry, 2017, 89, 10335-10342. Yi Zeng, Jia-Qiang Ren, Shao-Kai Wang, Jia-Ming Mai, Bing Qu, Yan Zhang, Ai-Guo Shen*, Ji-Ming Hu, Rapid and reliable detection of alkaline phosphatase by a hot spots amplification strategy based on well-controlled assembly on single nanoparticle, ACS Applied Materials Interfaces, 2017, 9, 29547-29553. Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen*, Ji-Ming Hu*, Field and pretreatment-free detection of heavy-metal ions in organic polluted water through an alkyne-coded SERS test kit, ACS Applied Materials Interfaces, 2016, 8, 27772-27778. Yong Chen, Jia-Qiang Ren, Xia-Guang Zhang, De-Yin Wu, Ai-Guo Shen*, Ji-Ming Hu*, Alkyne-modulated surface-enhanced Raman scattering-palette for optical interference-free and multiplex cellular imaging, Analytical Chemistry, 2016, 88, 6115-6119. Wei Fang, Xin-Wei Zhang, Yong Chen, Liang Wan, Wei-Hua Huang, Ai-Guo Shen*, Ji-Ming Hu*, Portable SERS-enabled micropipettes for microarea sampling and reliably quantitative detection of surface organic residues, Analytical Chemistry, 2015, 87, 9217-9224. Yong Chen, Xiang-Ru Bai, Le Su, Zhan-Wei Du, Ai-Guo Shen*, Arnulf Materny, Ji-Ming Hu*, Combined labelled and label-free SERS probes for triplex three-dimensional cellular imaging, Scientific Reports, 2016, 6, 19173. Yi Zeng, Jin-Ju Pei, Li-Hua Wang, Ai-Guo Shen*, Ji-Ming Hu, A sensitive sequential "on/off" SERS assay for heparin with wider detection window and higher reliability based on the reversed surface charge changes of functionalized Au@Ag nanoparticles, Biosensors and Bioelectronics, 2015, 66, 55-61. Li-Hua Wang, Yi Zeng, Ai-Guo Shen*, Xiao-Dong Zhou, Ji-Ming Hu*, Three dimensional nano-assemblies of noble metal nanoparticle-infinite coordination polymers as specific oxidase mimetics for degradation of methylene blue without adding any cosubstrate, Chemical Communications, 2015, 51, 2052-2055. Gan Qu, Guan-Nan Zhang, Zi-Tong Wu, Ai-Guo Shen*, Jian-Bo Wang, Ji-Ming Hu*, A "turn-off" SERS assay of heparin with high selectivity based on heparin-peptide complex and Raman labelled gold nanoparticles, Biosensors and Bioelectronics, 2014, 60, 124-129. Zi-Tong Wu, Yi-Zhen Liu, Xiao-Dong Zhou, Ai-Guo Shen*, Ji-Ming Hu*, A "turn-off" SERS-based detection platform for ultra-sensitive detection of thrombin based on enzymatic assays, Biosensors and Bioelectronics, 2013, 44, 10-15.

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