李英 - 南京信息工程大学 - 环境科学与工程学院

个人简介

Education 09/2006-01/2012Ph.D, Organic Chemistry Applying Aryltrifluoroborates as PET Imaging Agents Department of Chemistry, the University of British Columbia, Canada Supervisor: Dr. David M. Perrin 09/2003-06/2006 M.Sc., Organic Chemistry Synthesis of Nuclease Model Compounds and Research on Their Interaction with DNA School of Chemistry and Chemical Engineering, Nanjing University, China Supervisor: Guoyuan Lu 09/1999-07/2003 B.Sc., Applied Chemistry School of Chemistry and Chemical Engineering, Nanjing University, China Supervisor: Guoyuan Lu Working Experiences 07/2014-date Professor Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution Control, College of Environmental Science & Engineering, Nanjing University of Information Science & Technology 04/2013- 07/2014 Faculty Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution Control, College of Environmental Science & Engineering, Nanjing University of Information Science & Technology 10/2012-12/2014 Postdoctoral fellow Department of Physics, Nanjing University Supervisor: Dr. Wei Wang 01/2012-06/2012 Postdoctoral fellow Department of Chemistry, the University of British Columbia, Canada Supervisor: Dr. David M. Perrin

近期论文

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Li, Y.*, Sun, Y., Qing, M., Cao, Y.*, Wang, W.*, Mechanics of single peptide hydrogelator fibrils, Nanoscale, 2015, 7, 5638-5642. Liu, Z., Chao, D., Li, Y., Ting, R., Oh, J., Perrin, D.M.*, From Minutes to Years: Predicting Organotrifluoroborate Solvolysis Rates, Chemistry-A European Journal, 2015, 21(10), 3924-3928. Liu, Z., Li, Y., Ting, R., Perrin, D.M.*, Designing kinetically stable aryltrifluoroborates as 18F-capture agents for PET imaging, Journal of Physical Organic Chemistry, 2015, 28(3), 210-214. Wu, J., Chen, A., Qin, M., Huang, R., Zhang, G., Xue, B., Gao, X., Li, Y.*, Cao, Y.*, Wang, W.*, Hierarchical construction of a mechanically stable peptide-graphene oxide hybrid hydrogel for drug delivery and pulsatile triggered release in vivo, Nanoscale, 2015, 7(5), 1655-1660. Li, Y., Qin, M., Li, Y., Cao, Y.*, Wang, W.*, Single molecule evidences for the adaptive binding of DOPA to different wet surfaces, Langmuir, 2014, 30(15), 4358-4366. Xue, B., Li, Y., Qin, M., Cao, Y.*, Wang, W.*, Integrated artificial photosynthesis system based on peptide nanotubes, Nanoscale 2014 , 6(14), 7832-7837. Li, Y., Qin, M., Cao, Y.*, Wang, W.*, Designing the mechanical properties of peptide-based supramolecular hydrogels for biomedical applications, Science China-Physics, Mechanics & Astronomy, 2014, 57(5), 849-858. Li, Y.*, 18F-Labeling techniques for positron emission tomography, Science China-Chemistry, 2013, 56(12), 1682-1692. Xie, J., Li, Y., Cao, Y., Xu, C., Xia, M., Qin, M.*, Wei, J., Wang, W.*, Photo synthesis of protein-based drug delivery nanoparticles for active tumor targeting, Biomaterials Science, 2013, 1(12), 1216-1222. Ding, Y. ‡, Li, Y. ‡*, Qin, M.*, Cao, Y., Wang, W.*, Photo-cross-linking approach towards engineering small tyrosine-containing peptide hydrogels of enhanced mechanical stability, Langmuir, 2013, 29(23), 13299-13306. Li, Y., Schaffer, P., Perrin, D. M.*, Dual isotope labeling: Conjugation of 32P-oligonucleotides with 18F-aryltrifluoroborate via copper(I) catalyzed cycloaddition, Bioorganic and Medicinal Chemistry Letters, 2013, 23(23) 6313-6316. Li, Y., Liu, Z., Lozada, J., Wong, M.Q., Lin, K.-S., Yapp, D., Perrin, D.M.*, Single step 18F-labeling of dimeric cycloRGD for functional PET imaging of tumors in mice, Nuclear Medicine and Biology, 2013, 40(8), 959-966. Wu, L. ‡, Li, Y. ‡, Yang Y., Qin, M.*, Deciphering Structural and Functional Roles of Disulfide Bonds in Decorsin, Science China- Chemistry, 2013, 56(10), 1485-1492. Li, Y.*, Ding, Y., Qin, M.*, Cao, Y., Wang, W.*, An enzyme-assisted nanoparticle crosslinking approach to enhance the mechanical strength of peptide-based supramolecular hydrogels peptide-based supramolecular hydrogels, Chemical Communications, 2013, 49(77), 8653-8655. Liu, Z., Li, Y., Lozada, J., Wong, M.Q., Greene, J., Lin, K.-S., Yapp, D., Perrin, D.M.*, Kit-like 18F-labeling of RGD-19F-aryltrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivo tumor imaging, Nuclear Medicine and Biology, 2013, 40(6), 841-849. Ding, B. ‡, Li, Y. ‡*, Qin, M., Ding, Y., Cao, Y., Wang, W.*, Two approaches for the engineering of homogeneous small-molecule hydrogels, Soft Matter, 2013, 9(18), 4672-4680. Liu, Z., Li, Y., Lozada, J., Schaffer, P., Adam, M. J., Ruth, T. J., Perrin, D. M.*, Stoichiometric leverage: rapid 18F-aryltrifluoroborate radiosynthesis at high specific activity for click conjugation, Angewandte Chemie International Edition, 2013, 52(8), 2303-2307. Li, Y., Liu, Z., Harwig, C.W., Pourghiasian, M., Lau, J., Lin, K.-S, Schaffer, P., Benard, F., Perrin, D. M.*, 18F-Click labeling of a bombesin antagonist with an alkyne-18F-ArBF3-: in vivo PET imaging of tumors expressing the GRP-receptor, American Journal of Nuclear Medicine and Molecular Imaging, 2013, 3(1), 57-70. Li. Y., Guo, J., Tang, S., Lang, L., Chen, X., Perrin, D.M.*, One-step and one-pot-two-step radiosynthesis of cyclo-RGD-[18F]-aryltrifluoroborate conjugates for functional imaging, American Journal of Nuclear Medicine and Molecular Imaging, 2013, 3(1), 44-56. Liu, Z., Li, Y., Lozada J., Pan, J., Lin, K.-S., Schaffer, P., Perrin, D.M.*, Rapid, one-step, high yielding 18F-labeling of an aryltrifluoroborate bioconjugate by isotope exchange at very high specific activity, Journal of Labelled Compounds and Radiopharmaceuticals, 2012, 55(14), 491-496.