Mao, Chengde - Purdue University - Department of Chemistry

个人简介

B.S., 1986, Peking University; Ph.D., 1999, New York University; Postdoctoral Fellow, 1999-2000, New York University; Postdoctoral Fellow, 2001-2002, Harvard University.

研究领域

Our research lies at the interface between chemistry, biology, nanotechnology and materials science. It falls into two general themes: 1) developing nanotechnology with biochemical approaches; 2) applying nanotechnology to address fundamental problems in chemistry and biology.

近期论文

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Cheng Tian, Xiang Li, Zhiyu Liu, Wen Jiang, Guansong Wang & Chengde Mao, “Directed Self-Assembly of DNA Tiles into Complex Nanocages”, Angew. Chem. Int. Ed. (in press). Zhou Nie, Pengfei Wang, Cheng Tian & Chengde Mao, “Synchronization of Two Assembly Processes to Build Responsive DNA Nanostructures”, Angew. Chem. Int. Ed. (in press). Pengfei Wang, Cheng Tian, Xiang Li & Chengde Mao, “Assembly of Barcode-like Nucleic Acid Nanostructures”, Samll (in press). Tae-Gon Cha, Jing Pan, Haorong Chen, Janette Salgado, Xiang Li, Chengde Mao, Jung Hyun Choi. “A Synthetic DNA Motor That Transports Nanoparticles Along Carbon Nanotubes” Nat. Nanotechnol. 9, 39-42 (2014). Chenhui Hao, Xiang Li, Cheng Tian, Wen Jiang, Guansong Wang & Chengde Mao, “Construction of RNA Nanocages by Re-Engineering the Packaging RNA (pRNA) of Phi29 Bacteriophage”, Nat. Communications 5:3890 | DOI: 10.1038/ncomms4890. David A. Rusling, Arun Richard Chandrasekaran, Yoel P. Ohayon, Tom Brown, Keith R. Fox, Ruojie Sha, Chengde Mao & Nadrian C. Seeman, “Functionalizing Designer DNACrystals with a Triple-Helical Veneer”, Angew. Chem. Int. Ed. 53, 3979-3982 (2014) Xiang Li, Chenhui Hao, Cheng Tian, Pengfei Wang & Chengde Mao, “Vernier Assembly: Controlling DNA Polymerization via Length Mismatching”, Chem. Comm. 50, 6361-6363 (2014). Zhiyu Liu & Chengde Mao, “Reporting Transient Molecular Events by DNA Strand Displacement”, Chem. Comm. 50, 8239-8241 (2014). Nadrian C. Seeman, Chengde Mao & Hao Yan, “Guest Editorial: Nucleic Acid Nanotechnology”, Acc. Chem. Res. 47, 1643-1644 (2014). Chuan Zhang, Xiang Li, Cheng Tian, Guimei Yu, Yulin Li, Weng Jiang & Chengde Mao, “DNA Nanocages Swallow Gold Nanoparticles (AuNPs) to Form AuNP@DNA Cage Core-Shell Structures”, ACS Nano 8, 1130-1135 (2014). Hang Qian, Cheng Tian, Jinwen Yu, Fei Guo, Ming-Sen Zheng, Wen Jiang, Quan-Feng Dong & Chengde Mao, “Self-Assembly of DNA Nanotubes with Defined Diameters and Lengths”, Small 10, 855-858 (2014). Cheng Tian, Chuan Zhang, Xiang Li, Chenhui Hao, Shuajiang Ye & Chengde Mao, “Approaching the Limit: Can One DNA Strand Assemble into Defined Nanostructures?”, Langmuir 30, 5859-5862 (2013). Xueping Liu, Guansong Wang, Zaichun You, Pin Qian, Huaping Chen, Yin Dou, Zhenghua Wei, Yan Chen, Chengde Mao, Jianxiang Zhang, “Inhibition of Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells by a mTOR siRNA-Loaded Cyclodextrin Nanovector”, Biomaterials 35, 4401-4416 (2014). Yingmei Li, Chuan Zhang, Cheng Tian & Chengde Mao, “A Nanomotor Involves a Metastable, Left-handed DNA Duplex”, Org. Biomol. Chem. 12, 2543-2546 (2014). Zhou Nie, Xiang Li, Yingmei Li, Cheng Tian, Pengfei Wang & Chengde Mao, “Self-Assembly of DNA Nanoprisms with only Two Component Strands”, Chem. Comm. 49, 2807-2809 (2013). Pengfei Wang, Seung Hyeon Ko, Cheng Tian, Chenhui Hao & Chengde Mao, “RNA–DNA Hybrid Origami: Folding of a Long RNA Single Strand Into Complex Nanostructures Using Short DNA Helper Strands”, Chem. Comm. 49, 5462-5464 (2013). Ruojie Sha, Jens J. Birktoft, Nam Nguyen, Arun Richard Chandrasekaran, Jianping Zheng, Xinshuai Zhao, Chengde Mao & Nadrian C. Seeman, “Self-Assembled DNA Crystals: The Impact on Resolution of 5-Phosphates and the DNA Source”, Nano Lett. 13, 793-797 (2013). Zhiyu Liu, Yingmei Li, Cheng Tian & Chengde Mao, “A Smart DNA Tetrahedron That Isothermally Assembles or Dissociates in Response to the Solution pH Value Changes”, Biomacromolecules 14, 1711-1714 (2013). Huaping Chen, Xueping Liu, Yin Dou, Binfeng He, Li Liu, Zhenghua Wei, Jin Li, Changzheng Wang, Chengde Mao, Jianxiang Zhang & Guansong Wang, “A Ph-Responsive Cyclodextrin-Based Hybrid Nanosystem As A Nonviral Vector For Gene Delivery”, Biomaterials 34, 4159-4172 (2013). Chuan Zhang, Cheng Tian, Xiang Li, Hang Qian, Chenhui Hao, Wen Jiang & Chengde Mao, “Reversibly Switching the Surface Porosity of a DNA Tetrahedron”, J. Am. Chem. Soc. 134, 11998-12001 (2012).