黄卫华 - 武汉大学 - 化学与分子科学学院

个人简介

B.S., 1996, Wuhan University, Wuhan, China Ph.D., 2002, Wuhan University, Wuhan, China Associate Professor, 2004-2007, Wuhan University, Wuhan, China Post-Doctoral Research Fellow, 2005-2006, École Normale Supérieure, Paris, France Professor, 2007-current, Wuhan University, Wuhan, China

研究领域

Bioanalytical chemistry, Micro and nanoelectrode, Microfluidics, Single cell analysis His primary research interests focus on development of micro or nanoscale analytical techniques and explore their use in the monitoring of single cells.

近期论文

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Mechanical Strain Induces and Increases Vesicular Release Monitored by Microfabricated Stretchable Electrodes 2024Jing Yan, Fu-Li Zhang, Kai-Qi Jin, Jia-Xin Li, Li-Jun Wang, Wen-Ting Fan, Wei-Hua Huang*, Yan-Ling Liu*Angew. Chem. Int. Ed. 2024, e202403241 Nanoelectrochemistry Reveals How Presynaptic Neurons Regulate Vesicle Release to Sustain Synaptic Plasticity under Repetitive Stimuli 2024Fu-Li Zhang, Xiao-Ke Yang, Yu-Ting Qi, Si-Yu Tian and Wei-Hua Huang*Chem. Sci. 2024, Accepted Manuscript Transcriptomic Signature of 3D Hierarchical Porous Chip Enriched Exosomes for Early Detection and Progression Monitoring of Hepatocellular Carcinoma 2024Kezhen Yi, Yike Wang, Yuan Rong, Yiru Bao, Yingxue Liang, Yiyi Chen, Fusheng Liu, Shikun Zhang, Yuan He, Weihuang Liu, Chengliang Zhu, Long Wu, Jin Peng, Hao Chen, Weihua Huang, Yufeng Yuan*, Min Xie*, and Fubing Wang*Adv. Sci. 2023, 2305204 Real-Time Quantification of Nanoplastics-Induced Oxidative Stress in Stretching Alveolar Cells 2024Yi Zhao, Wen-Ting Fan, Kai-Qi Jin, Jing Yan, Yu-Ting Qi, Wei-Hua Huang*, and Yan-Ling Liu*ACS Nano 2024, 18, 8, 6176–6185 Nanosensor Detection of Reactive Oxygen and Nitrogen Species Leakage in Frustrated Phagocytosis of Nanofibers 2024Yu-Ting Qi, Fu-Li Zhang, Si-Yu Tian, Hui-Qian Wu, Yi Zhao, Xin-Wei Zhang, Yan-Ling Liu, Pingqing Fu, Christian Amatore*, and Wei-Hua Huang*Nat. Nanotechnol. 2024, 19, 524-533 Fast Antioxidation Kinetics of Glutathione Intracellularly Monitored by a Dual-Wire Nanosensor 2023Yu-Ting Jiao, Yi-Ran Kang, Ming-Yong Wen, Hui-Qian Wu, Xinwei Zhang, Wei-Hua Huang Angew. Chem. Int. Ed. 2023, e202313612 Cordycepin regulates intracellular glutathione homeostasis to achieve anti-aging effect as revealed by nanoelectrochemistry 2023Wen-Tao Wu, Wen-Ting Fan, Yi-Ke Wang, Wei-Hua Huang*Chin. Sci. Bull. 2023, 68, 30, 4063-4072 Current progress and prospect of microfluidic-based exosome investigation 2023Yi-Ke Wang, Yi-Ru Bao, Ying-Xue Liang, Yi-Jing Chen, Wei-Hua Huang*, Min Xie*Trac-Trends Anal. Chem. 2023, 168, 117310 Vasculature-on-a-chip with stretchable sensor for recapitulating hemodynamics and electrochemical monitoring of endothelium 2023Wen-Ting Fan, Yi Zhao, Feng Hong, Yan-Ling Liu*, Wei-Hua Huang*Sci. China Chem. 2023, 66, 3314–3322 Flexible and Stretchable Electrochemical Sensors for Biological Monitoring 2023Yi Zhao, Kai-Qi Jin, Jing-Du Li, Kai-Kai Sheng, Wei-Hua Huang*, and Yan-Ling Liu*Adv. Mater. 2023, 2305917. Three-Dimensional Stretchable Sensor-Hydrogel Integrated Platform for Cardiomyocyte Culture and Mechanotransduction Monitoring 2023Ming Chen, Yu Qin, Wen-Ting Fan, Jing Yan, Feng Hong, Wei-Hua Huang*, and Yan-Ling Liu*Anal. Chem. 2023, 95, 34, 12859-12866 Nanofiber-based Stretchable Electrodes for Oriented Culture and Mechanotransduction Monitoring of Smooth Muscle Cells 2023Chen-Xi Bi, Kai-Qi Jin, Jing Yan, Yu Qin, Feng Hong, Wei-Hua Huang*, and Yan-Ling Liu*ACS Sens. 2023, 8, 8, 3248-3256 Nanoelectrochemistry reveals how soluble Aβ42 oligomers alter vesicular storage and release of glutamate 2023Xiao-Ke Yang, Fu-Li Zhang, Xue-Ke Jin, Yu-Ting Jiao, Xin-Wei Zhang, Yan-Ling Liu, Christian Amatore*, Wei-Hua Huang*Proc. Natl. Acad. Sci. U S A. 2023, 120, e2219994120. An anti-poisoning nanosensor for in situ monitoring of intracellular endogenous hydrogen sulfide 2023Xi Chen, Wen-Tao Wu, Yu-Ting Jiao, Yi-Ran Kang, Xin-Wei Zhang*, Wei-Hua Huang*Chem. Commun. 2023, 59, 1773 Dual-channel nanoelectrochemical sensor for monitoring intracellular ROS and NADH kinetic variations of their concentrations 2023Yu-Ting Jiao, Hong Jiang, Wen-Tao Wu, Yu-Ting Qi, Ming-Yong Wen, Xiao-Ke Yang, Yi-Ran Kang, Xin-Wei Zhang, Christian Amatore*, Wei-Hua Huang*Biosens. Bioelectron. 2023, 222, 114928 Homeostasis inside Single Activated Phagolysosomes: Quantitative and Selective Measurements of Submillisecond Dynamics of Reactive Oxygen and Nitrogen Species Production with a Nanoelectrochemical Sensor 2022Yu-Ting Qi, Hong Jiang, Wen-Tao Wu, Fu-Li Zhang, Si-Yu Tian, Wen-Ting Fan, Yan-Ling Liu, Christian Amatore*, and Wei-Hua Huang* J. Am. Chem. Soc. 2022, DOI: 10.1021/jacs.2c01857 Redox Homeostasis Alteration in Endothelial Mechanotransduction Monitored by Dual Stretchable Electrochemical Sensors 2022Wen-Ting Fan, Yi Zhao, Wen-Tao Wu, Yu Qin, Jing Yan, Yan-Ling Liu*, and Wei-Hua Huang* Anal. Chem. 2021., DOI: 10.1021/acs.analchem.2c01227 A three-dimensional electrochemical biosensor integrated with hydrogel for cells culture and lactate release monitoring. Chun-Ying Yao#, Yu Qin#, Wen-Ting Fan, Li-Ping Yan, Ming Chen, Yan-Ling Liu, Wei-Hua Huang*J. Electroanal. Chem. 2022, 915, 116338-116345 (invited) Soft Electrodes for Electrochemical and Electrophysiological Monitoring of Beating Cardiomyocytes. Li-Ping Yan#, Ming-Yong Wen#, Yu Qin, Chen-Xi Bi, Yi Zhao, Wen-Ting Fan, Jing Yan, Wei-Hua Huang*, and Yan-Ling Liu* Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202203757 Versatile Construction of Biomimetic Nanosensors for Electrochemical Monitoring of Intracellular Glutathione. Wen-Tao Wu, Xi Chen, Yu-Ting Jiao, Wen-Ting Fan, Yan-Ling Liu, and Wei-Hua Huang* Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202115820 Plasticizer and Catalyst Co-Functionalized PEDOT:PSS Enables Stretchable Electrochemical Sensing of Living Cells. Jing Yan, Yu Qin, Wen-Ting Fan, Wen-Tao Wu, Song-Wei Lv, Li-Ping Yan, Yan-Ling Liu* and Wei-Hua Huang Chem. Sci. 2021, 12, 14432-14440 Large-Scale Synthesis of Functionalized Nanowires to Construct Nanoelectrodes for Intracellular Sensing（VIP）. Wen-Tao Wu, Hong Jiang, Yu-Ting Qi, Wen-Ting Fan, Jing Yan, Yan-Ling Liu, Wei-Hua Huang* Angew. Chem. Int. Ed. 2021, DOI: 10.1002/anie.202106251 A Stretchable Scaffold with Electrochemical Sensing for 3D Culture, Mechanical Loading, and Real-Time Monitoring of Cells. Yu Qin, Xue-Bo Hu, Wen-Ting Fan, Jing Yan, Shi-Bo Cheng, Yan-Ling Liu*, and Wei-Hua Huang*Adv. Sci. 2021, 8, 2003738-2003747 A Three-Dimensional Electrochemical Biosensor Integrated with Hydrogel Enables Real-Time Monitoring of Cells under Their In Vivo-like Microenvironment. Xue-Bo Hu, Yu Qin, Wen-Ting Fan, Yan-Ling Liu*, Wei-Hua Huang Anal. Chem. 2021, 93, 22, 7917–7924 Quantitative Nano-Amperometric Measurement of Intravesicular Glutamate Content and of its Sub-Quantal Release by Living Neurons. Xiao-Ke Yang#, Fu-Li Zhang#, Wen-Tao Wu, Yun Tang, Jing Yan, Yan-Ling Liu, Christian Amatore*, and Wei-Hua Huang* Angew. Chem. Int. Ed. 2021, DOI: 10.1002/anie.202100882 Three Dimensional Conductive Scaffold Microchip for Effective Capture and Recover of Circulating Tumor Cells with High Purity. Shi-Bo Cheng#, Miao-Miao Chen#, Yi-Ke Wang, Zi-Han Sun, Yu Qin, Shan Tian, Wei-Guo Dong*, Min Xie*, Wei-Hua Huang Anal. Chem. 2021, 93, 7102-7109 Harpagide Inhibits Microglial Activation and Protects Dopaminergic Neurons as Revealed by Nanoelectrode Amperometry. Fu‐Li Zhang#, Yun Tang#, Hong Jiang, Xiao‐Ke Yang, Wei‐Hua Huang*Chin. J. Chem. 2021, DOI: 10.1002/cjoc.202100178 Stretchable Electrochemical Sensors for Cell and Tissue Detection. Yan-Ling Liu, Wei-Hua Huang* Angew. Chem. Int. Ed. 2021, 60, 2757-2767 Construction of micro-nano electrochemical sensing interfaces for real-time monitoring of single cells. Yu-Ting Qi#, Fu-Li Zhang#, Si-Yu Tian, Xiao-Ke Yang, Yan-Ling Liu, Wei-Hua Huang*Sci. Sin. Chim. 2020, 51, 359-373 Stretchable Electrode Based on Au@Pt Nanotube Networks for Real-Time Monitoring of ROS Signaling in Endothelial Mechanotransduction. Wen-Ting Fan, Yu Qin, Xue-Bo Hu, Jing Yan, Wen-Tao Wu, Yan-Ling Liu*, and Wei-Hua Huang Anal. Chem. 2020. 92, 23, 15639–15646 Intracellular monitoring of NADH release from mitochondria using a single functionalized nanowire electrode. Hong Jiang, Yu-Ting Qi, Wen-Tao Wu, Ming-Yong Wen, Yan-Ling Liu and Wei-Hua Huang* Chem. Sci. 2020, 11, 8771-8778 Flexible Three-Dimensional Net for Intravascular Fishing of Circulating Tumor Cells. Shi-Bo Cheng, Ming Wang , Chi Zhang, Miao-Miao Chen, Yi-Ke Wang, Shan Tian, Na Zhan, Wei-Guo Dong, Min Xie*, and Wei-Hua Huang* Anal. Chem. 2020, 92, 7, 5447–5455 High Efficient Isolation of Tumor Cells by a Three Dimensional Scaffold Chip for Diagnosis of Malignant Effusions. Shan Tian, Shi-Bo Cheng, Ying-Yun Guo, Min Xie*, Na Zhan, Zhi Zeng, Wei-Hua Huang, and Wei-Guo Dong* ACS Appl. Bio Mater. 2020, 3, 4, 2177–2184 Mechanical Distension Induces Serotonin Release from Intestine as Revealed by Stretchable Electrochemical Sensing. Yan-Ling Liu, Yan Chen, Wen-Ting Fan, Pan Cao, Jing Yan, Xing-Zhong Zhao, Wei-Guo Dong*and Wei-Hua Huang* Angew.Chem.Int. Ed. 2020, 59,4075–4081 Harpagide, a natural product, promotes synaptic vesicle release as measured by nanoelectrode amperometry. Yun Tang, Xiao-Ke Yang, Xin-Wei Zhang, Wen-Tao Wu, Fu-Li Zhang, Hong Jiang, Yan-Ling Liu, Christian Amatore* and Wei-Hua Huang* Chem. Sci. 2020, 11, 778-785