研究领域
应用电化学,医用电极
电化学和医学工程、神经工程的交叉研究是一个快速发展和日益受到关注的领域,其研究成果已成为传统治疗方法以外的一种全新的康复治疗方法,同时提供研究大脑相关生命现象的技术手段。 本课题组的研究兴趣包括:
1、植入电极的安全性和生物相容性研究;
2、微机电系统MEMS制备的神经电极阵列的表征、封装、涂层技术;
3、新型的脑-机接口、人-机接口的电极传感器;
4、应用于高端医疗设备,工业和海洋环境监测以及石油探测电极传感器.
近期论文
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Zhou H, Cheng X, Rao L, Li T, Duan YY*. Poly(3,4-ethylenedioxythiophene)/multi-wall carbon nanotubes composite coatings for improving stability of microelectrodes in neural prostheses applications.Acta Biomaterialia, 2013, Accept.
Zhou H, Wang T,Duan YY*. A simple method for amino-functionalization of carbon nanotubes and electrodeposition to modify neural microelectrodes.Journal of Electroanalytical Chemistry, 2013, 688C: 69-75.
Rao L, Zhou H, Li T, Li CY, Duan YY*. Polyethylene glycol-containing polyurethane hydrogel coatings for improving the biocompatibility of neural electrodes.Acta Biomaterialia.2012. 8 (6): 2233-2242.
Cheng X, Li T, Zhou H, Zhang Q, Tan J, Gao W, Wang J, Li C, Duan YY*. Cortical electrical stimulation with varied low frequencies promotes functional recovery and brain remodeling in a rat model of ischemia. Brain Research Bulletin, 2012; 89 (3-4):124-132.
Zhou H, Li T, Duan YY*. Reduce impedance of intracortical iridium oxide microelectrodes by hydrogel coatings. Sensors and Actuators B: Chemical, 2012;161(1):198-202.
Lu Y, Li T, Zhao X, Li M, Cao Y, Yang H, Duan YY*. Electrodeposited polypyrrole/carbon nanotubes composite films electrodes for neural interfaces.Biomaterials, 2010;31(19):5169-5181.
Zhou Q, Zhang Q, Zhao X, Duan YY*, Lu Y, Li C, Li T. Cortical electrical stimulation alone enhances functional recovery and dendritic structures after focal cerebral ischemia in rats. Brain Research, 2010;1311:148-157.
Lu Y, Wang D, Li T, Zhao X, Cao Y, Yang H, Duan YY*. Poly(vinyl alcohol)/poly(acrylic acid) hydrogel coatings for improving electrode-neural tissue interface. Biomaterials, 2009;30(25):4143-4151.
Lu Y, Wang T, Cai Z, Cao Y, Yang H, Duan YY*. Anodically electrodeposited iridium oxide films microelectrodes for neural microstimulation and recording. Sensors and Actuators B: Chemical, 2009;137(1):334-339.
Li T, Zhou Q, Lu Y, Zhang Q, Wang DF, Li CY, Duan YY*. The feasibility and efficacy of the low intensity cortical electrical stimulation after MCAO in rats. Journal of the Neurological Sciences, 2009;285:S219-S219.
Lu Y, Cai Z, Cao Y, Yang H, Duan YY*. Activated iridium oxide films fabricated by asymmetric pulses for electrical neural microstimulation and recording. Electrochemistry Communications, 2008;10(5):778-782.
Duan YY*, Clark GM, Cowan RSC. A study of intra-cochlear electrodes and tissue interface by electrochemical impedance methods in vivo. Biomaterials, 2004;25 (17):3813-3828.