个人简介
1997─2000: M.S., Department of Chemistry, Central South University, China (Supervisor: Professor Younian Liu)
2000─2003: Ph.D., Shanghai Institute of Organic Chemistry (SIOC) (Supervisor: Professor Min Shi)
2003─2006: Postdoctoral Fellow, Department of Chemistry, Penn State University (Supervisor: Professor Xumu Zhang)
2006─2008: Associate Professor, College of Chemistry and Molecular Sciences, Wuhan University
2008─present: Professor, College of Chemistry and Molecular Sciences, Wuhan University
研究领域
Our current research interests focus on asymmetric catalysis with efforts to develop novel and practical methodologies for the efficient construction of biologically active and synthetically useful molecules, including heterocyclic compounds and nonproteinogenic α-amino acids (α-AAs), etc.
Catalytic Asymmetric 1,3-Dipolar Cycloaddition
Catalytic Asymmetric Diels-Alder/Formal [4+2]-Cycloaddition
Design and Synthetic Application of Bifunctional Organocatalysts
近期论文
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Stereodivergent Construction of 1,4-Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis Xin Chang, Xiang Cheng, Xue-Tao Liu, Cong Fu, Wei-Yi Wang, Chun-Jiang Wang* Angew. Chem. Int. Ed., 2022, e202206517 DOI: 10.1002/anie.202206517
Design, Synthesis and Application of Multifunctional Chiral Aminophosphine Catalyst for Asymmetric Intermolecular Cross Rauhut-Currier Reaction Wu-Wei Dong, Kui Tian, Xiu-Qin Dong,* and Chun-Jiang Wang* Chin. J. Chem., 2022, 40, 2061-2066 DOI: 10.1002/cjoc.202200205
Stereodivergent synthesis of enantioenriched azepino[3,4,5-cd]-indoles via cooperative Cu/Ir-catalyzed asymmetric allylic alkylation and intramolecular Friedel–Crafts reaction Lu Xiao, Bo Li, Fan Xiao, Cong Fu, Liang Wei, Yanfeng Dang*, Xiu-Qin Dong* and Chun-Jiang Wang* Chem. Sci., 2022, 13, 4801-4812 DOI: 10.1039/D1SC07271D
Catalytic asymmetric synthesis of enantioenriched α-deuterated pyrrolidine derivatives Xin Chang, Xiang Cheng and Chun-Jiang Wang* Chem. Sci., 2022, 13, 4041-4049 DOI: 10.1039/D2SC00826B
Synthesis of bioactive fluoropyrrolidines via copper(i)-catalysed asymmetric 1,3-dipolar cycloaddition of azomethine ylides Xiao Xu, Longzhu Bao, Lu Ran, Zhenyan Yang, Dingce Yan, Chun-Jiang Wang* and Huailong Teng* Chem. Sci., 2022, 13, 1398-1407 DOI: 10.1039/D1SC04595D
Asymmetric Synthesis of Chiral Aza-macrodiolides via Iridium-Catalyzed Cascade Allylation/Macrolactonization Qi Xiong, Lu Xiao, Xiu-Qin Dong*, and Chun-Jiang Wang* Org. Lett., 2022, 24, 2579-2584 DOI: 10.1021/acs.orglett.2c00942
Iridium-catalyzed asymmetric double allylic alkylation of azlactone: efficient access to chiral α-amino acid derivatives Xiang Cheng, Chong Shen, Xiu-Qin Dong* and Chun-Jiang Wang* Chem. Commun., 2022, 58, 3142-3145 DOI: 10.1039/D2CC00328G
Catalytic Asymmetric Benzylation of Azomethine Ylides Enabled by Synergistic Lewis Acid/Palladium Catalysis Xin Chang, Jing-Di Ran, Xue-Tao Liu, and Chun-Jiang Wang* Org. Lett., 2022, 24, 2573-2578 DOI: 10.1021/acs.orglett.2c00865
Stereodivergent Synthesis of Carbocyclic Quaternary α-Amino Acid Derivatives Containing Two Contiguous Stereocenters Cong Fu, Qi Xiong, Lu Xiao, Ling He, Tian Bai, Zongpeng Zhang, Xiu-Qin Dong* and Chun-Jiang Wang* Chin. J. Chem., 2022, 40, 1059-1065 DOI: 10.1002/cjoc.202100824
Stereodivergent synthesis via iridium-catalyzed asymmetric double allylic alkylation of cyanoacetate Chong Shen, Xiang Cheng, Liang Wei, Ruo-Qing Wang and Chun-Jiang Wang* Chem. Sci., 2021, 12, 15882-15891 DOI: 10.1039/D1SC06115A
Stereodivergent Synthesis of Enantioenriched γ-Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis Lu Xiao, Dr. Liang Wei, Prof. Dr. Chun-Jiang Wang* Angew. Chem. Int. Ed., 2021, 60, 24930-24940 DOI: 10.1002/anie.202107418
Asymmetric Synthesis of Axially Chiral Naphthyl-C3-indoles via a Palladium-Catalyzed Cacchi Reaction Cong-Shuai Wang, Liang Wei, Cong Fu, Xin-Heng Wang, and Chun-Jiang Wang* Org. Lett., 2021, 23, 7401-7406 DOI: 10.1021/acs.orglett.1c02574
Recent advances in catalytic asymmetric aza-Cope rearrangement Liang Wei and Chun-Jiang Wang* Chem. Commun., 2021, 57, 10469-10483 DOI: 10.1039/D1CC04387K
Palladium catalyzed cascade umpolung allylation/acetalation for the construction of quaternary 3-amino oxindoles Xi-Shang Sun, Xin Chang, Li-Min Shi, Zuo-Fei Wang, Liang Wei* and Chun-Jiang Wang* Chem. Commun., 2021, 57, 7958-7961 DOI: 10.1039/D1CC03075B
Diastereoselective synthesis of functionalized tetrahydropyridazines containing indole scaffolds via an inverse-electron-demand aza-Diels–Alder reaction Taotao Chen, Chao Che, Zhefei Guo, Xiu-Qin Dong* and Chun-Jiang Wang* Org. Chem. Front., 2021, 8, 4392-4398 DOI: 10.1039/D1QO00623A
Cu-catalyzed endo-selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with ethenesulfonyl fluorides: Efficient access to chiral pyrrolidine-3-sulfonyl fluorides Yi-Nan Li, Xin Chang, Qi Xiong, Xiu-Qin Dong* and Chun-Jiang Wang* Chinese Chemical Letters, 2021, 32, 4029-4032 DOI: 10.1016/j.cclet.2021.05.063
Synergistic Cu/Pd-catalyzed asymmetric allylation: a facile access to α-quaternary cysteine derivatives Hui-Min Wu, Zongpeng Zhang, Liang Wei*, Xiu-Qin Dong* and Chun-Jiang Wang* Chem. Commun., 2021, 57, 6538-6541 DOI: 10.1039/D1CC01754C
Palladium-Catalyzed Asymmetric Allylic Alkylation/α-Iminol Rearrangement: A Facile Access to 2-Spirocyclic-Indoline Derivatives Xin Chang, Chao Che, Zuo-Fei Wang and Chun-Jiang Wang* CCS Chem., 2021, 3, 1484-1498 DOI: 10.31635/ccschem.021.202100875
β-Substituted Alkenyl Heteroarenes as Dipolarophiles in the Cu(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides Empowered by a Dual Activation Strategy: Stereoselectivity and Mechanistic Insight Xin Chang, Yuhong Yang, Chong Shen, Kun-Shan Xue, Zuo-Fei Wang, Hengjiang Cong, Hai-Yan Tao, Lung Wa Chung*, and Chun-Jiang Wang* J. Am. Chem. Soc., 2021, 143, 3519-3535 DOI: 10.1021/jacs.0c12911
Visible‐Light‐Enabled Enantioconvergent Synthesis of α‐Amino Acid Derivatives via Synergistic Brønsted Acid/Photoredox Catalysis Chao Che, Yi‐Nan Li, Xiang Cheng, Yi‐Nan Lu, Prof. Dr. Chun‐Jiang Wang* Angew. Chem. Int. Ed., 2021, 60, 4698-4704 DOI: 10.1002/anie.202012909
Synergistic Catalysis with Azomethine Ylides Liang Wei, Chun-Jiang Wang* Chin. J. Chem., 2021, 39, 15-24 DOI: 10.1002/cjoc.202000380
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