Lyon, Angeline - Purdue University - Department of Biological Sciences

个人简介

B.A. Biochemistry, 2004 University of Texas at Austin; Ph.D., 2009 University of Texas at Austin; Postdoctoral Fellow 2009-2014, University of Michigan

近期论文

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Lyon, A.M., Begley, J.A., Manett, T.D., and Tesmer, J.J.G., Molecular Mechanisms of PLCβ3 Autoinhibition, Structure 2014, 22, , 1844-1854 , Lyon, A.M., Dutta, S., Boguth, C.A., Skiniotis, G., and Tesmer, J.J.G., Structure of Full-Length Phospholipase C β3 in Complex with Gαq Reveals Functional Interfaces of its Cterminal Coiled-Coil Domain, Nat. Struct. Mol. Biol. 2013, 20, , 355-362 , Lyon, A.M., Tesmer, V.M., Dhamsania, V. D., Thal, D.M., Gutierrez, J., Chowdhury, S., Suddala, K., Northup, J.K., and Tesmer, J.J.G., An Autoinhibitory Helix in the C-Terminal Region of Phospholipase Cβ Represses Basal Activity and Mediates Gαq Activation, Nat. Struct. Mol. Biol. 2011, 18, , 999-1005 ,