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研究领域

1.催化不对称合成(新手性催化剂和新不对称反应类型的设计与研究); 2.基于新不对称催化策略合成小分子天然产物和药物活性分子;金属催化的反应方法学研究。

近期论文

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Amino Acid Salts Catalyzed Asymmetric Aldol Reaction of Tryptanthrin: A Straightforward Synthesis of Phaitanthrin A and Its Derivatives. Guowei Kang, Zhenli Luo, Chongxing Liu, Hang Gao, Quanquan Wu, Huayue Wu,* Jun Jiang*,Org. Lett. 2013,15(18),4738–4741 Catalytic Stereoselective Conjugate Addition of Oxindole to Electron-deficient Alkynes. Guowei Kang, Quanquan Wu, Miaochang Liu, Qingfang Xu, Zunyang Chen, Weilong Chen, Yuqiang Luo, Wei Ye, Jun Jiang*, Huayue Wu*, Adv. Synth. Catal. 2013, 355, 315-320. Regioselectivity-Reversed Asymmetric Aldol reaction of 1, 3-Dicarbonyl Compounds. H. Liu, H. Wu*, Z. Luo, J. Shen, G. Kang, B. Liu, Z. Wan, J. Jiang*. Chem. Eur. J., 2012, 18, 11899-11903. Asymmetric Organocatalytic Synthesis of β-Hydroxyynones with Quaternary Carbon Center under Aqueous Conditions. G. Kang Liu, H. Wu*, J. Jiang* J. Braz. Chem. Soc. 2012, 23, 5-10. Determination of Enantiomeric Compositions of Ibuprofen by Infrared Spectrometry with Catalytic Amount of Simple Chiral Recognition Reagent. X. Chen, X. Zhu, J. Jiang*. African Journal of Pharmacy and Pharmacology. 2011, 5, 731-736. Organocatalytic Asymmetric Three-Component Cyclization of Cinnamaldehydes and Primary Amines with 1,3-Dicarbonyl Compounds: Straight forward Access to Enantiomerically Enriched Dihydropyridines. Jun Jiang, Jie Yu, Xi-Xi Sun, Qin-Quan Rao, and Liu-Zhu Gong*.Angew. Chem., Int. Ed. 2008, 47, 2458-2462. Asymmetric Synthesis of 3-Amino d-Lactams and Benzo[a]quinolizidine by Catalytic Cyclization Reactions involving Azlactones Jun Jiang, Jian Qing, Liu-Zhu Gong*. Chem. Eur. J. 2009, 15, 7031-7034. Enantioselective Desymmetrization of Prochiral Cyclohexanone Derivatives via the Organocatalytic Direct Aldol Reaction. Jun Jiang, Long He, Shi-Wei Luo, Lin-Feng Cun, and Liu-Zhu Gong*.Chem. Comun. 2007, 736-738. Highly diastereo- and enantioselective direct aldol reactions of cycloketones with aldehydes catalyzed by a trans-4-tert-butyldimethylsiloxy-L-proline amide. Long He*, Jun Jiang, Zhuo Tang, Xin Cui, Ai-Qiao Mi, Yao-Zhong Jiang and Liu-Zhu Gong. Tetrahedron:Asymmetry.2007, 18, 265-270.

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